Student Theses and Dissertations

 

The Rockefeller University has awarded over one thousand Ph.D’s since 1959. This collection contains theses beginning with the graduating class of 2006. Earlier theses are added by request or as permission to digitize is received. For more information visit the FAQ page.

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2009

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Population Dynamics In A Model Closed Ecosystem, Doeke Romke Hekstra

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Synaptic Protein Profiling in the Mammalian Brain, Elizabeth Heller

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Mechanistic and Physiological Studies of the Insulin-Dependent Regulation of FOXA2, Jessica Jean Howell

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Architecture of a Coat for the Nuclear Pore Membrane, Kuo-Chiang Hsia

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Biophysical Characterization of Structure and Dynamics of Nuclear Pore Complex Components, Martin Kampmann

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Transfer Properties of the Hair Cell-Afferent Fiber Synapse, Erica C. Keen

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The Neural Circuitry Of Social Behavior In C. elegans, Evan Z. Macosko

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The Manipulation Of Apical Dendritic Plasticity And The Consequences For The Effects of Chronic Stress, Trudy McCall

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Novel Roles for the Tissue Plasminogen Activator System in the Development of Fetal Alcohol Syndrome and the Regulation of Contextual Learning After Stress, Melissa Noel-Castro

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Specification And Function Of Early Hair Follicle Stem Cells, Jonathan Nowak

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Fibrin Formation and Dissolution in the Progression of Amyloid-Beta Pathology in Alzheimer's Disease, Justin Paul

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Perceptual Learning, Long-Range Horizontal Connections And Top-Down Influences In Primary Visual Cortex, Valentin Piëch

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Dissecting the Development and Function of C. elegans Glia with Mutations of the mls-2 and vab-3 Genes, Yoshimura Satoshi

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Regulation of Apoptosis by XIAP Ubiquitin- Ligase Activity, Andrew James Schile

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Hierarchy and CIS-Regulation in Drosophila Segmentation: Rules for Pattern Formation and Clues to Evolution, Mark David Schroeder

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Regulation of Gene Expression in Trypanosoma brucei, Tim Nicolai Siegel

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The Role and Fate of Branch Site-U2 snRNA Interaction During Pre-mRNA Splicing, Duncan Smith

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Physiological Effects of Estradiol in the Mouse Hippocampal Formation, Joanna L. Spencer

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Of Mice and Men: Studying Innate and Adaptive Immunity Against the Epstein-Barr Virus, Till Strowig

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Regulation of Immunoglobulin Gene Diversification By Noncoding RNA's, Grace Teng

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Biochemical Analysis of the Protein-Protein Interactions Involved in Karyopherin-Mediated Transport Across the Nuclear Pore Complex, Jaclyn Tetenbaum-Novatt

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Dissecting the Functions of Classical Cadherins in Skin, Christopher Tinkle

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Structural Studies of Three Factors That Affect the Prokaryotic Transcription Cycle; Microcin J25, LAMBDA Q and T4 GP33, Kelly-Anne Fisi Twist

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An In Vivo Characterization of the Functional Role of Two Novel Genes: StARD5 and ADAM11, Marc Paul Waase

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Circuit Dynamics of Adult Visual Cortex, Homare Yamahachi

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Biochemical and Genetic Studies of Beclin 1 Function in Autophagy, Yun Zhong

2008

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Tuning of the Active Hair Bundle, Omar Ahmad

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Cracking the Odor Code: Molecular and Cellular Deconstruction of the Olfactory Circuit of Drosophila Larvae, Kenta Asahina

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The Differential Contribution of Striatonigral and Striatopallidal Neurons in Mediating Responses to Therapeutic Agents and Drugs of Abuse: A Dual Role for DARPP-32, Helen S. Bateup

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Proteomic, Bioinformatic and Functional Characterization of the Nuclear Pore Complex of the African Trypanosome, Jeffrey Allen DeGrasse

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The Hu Syndrome: At the Intersection of Cancer and Autoimmunity, Ilana J. DeLuca

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Further Insight into the Two Functions of Telomeres: Determining the Role of Tankyrase1 in Telomere Length Regulation and Tin2 in Telomere Protection, Jill Donigian

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Role of AID and microRNA-155 in c-myc-IgH Translocations, Yair Dorsett

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Discovery of the First Endogenous Gain of Function Mutation in Drosophila RAS1 as a Dominant Suppressor of Apoptosis, Christopher Gafuik

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Semi-Synthesis of the Transcription Factor SMAD2 Containing Caging Groups and Phosphoaminoacid Analogues, Michael Eric Hahn

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A Novel Phosphorylation Site in the Telomeric Protein TRF2 is Regulated by the ATR Kinase and Plays a Role in Relieving Replication Stress at the Telomere, Kristina Hoke

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Structural Analysis of Cycle Inhibiting Factor from Pathogenic Escherichia Coli, Yun-Yuan Hsu

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A Structural and Biochemical Analysis of the Drosophila Protein Period, Heather Anne King

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Structural and Computational Studies of RNA Polymerase, William J. Lane

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The Role of GDF-3 in Patterning the Early Embryo, Ariel Levine

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Visualizing Dendritic Cells In Vivo, Randall L. Lindquist

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Histone Modifications in Trypanosoma Brucei, Veena Mandava

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Dendritic Cell Regulation of Peripheral Tolerance in Polyclonal T Cell Repertoires, Revati F. Masilamani

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Dividing the Preplate: Characterization of Neuronal Subpopulations in the Early Murine Cerebral Cortex, Hilleary Botts Osheroff

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Small Molecules as Probes for Cell Division and Intracellular Transport, Ulf Peters

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Bioluminescence-Based High Precision Bacterial Growth Rate Measurements and Their Potential Application in Quantifying Deleterious Effects of High Mutation Rates, Sri Ram

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Conditional Protein Alleles and Regulation of Bacterial Transcription: A Thesis in Two Acts, Edmund Ching Schwartz

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Cellular and Molecular Mechanisms Underlying Leptin’s Metabolic Effects, Amandeep Singh

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Crystal Structure and Mechanism of Lysine Specific Demethylase-1, Pete G. Stravropoulos

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The Apollo Nuclease Binds To TRF2 and Protects, Megan van Overbeek

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Dendritic Cells in Normal and Inflamed Human Skin, Lisa C. Zaba

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Identification of Loss of Specific FMRP-RNA Interactions as a Cause of Fragile X Syndrome, Julie B. Zang

2007

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A New Type of Programmed Cell Death in C. Elegans, Mary C. Abraham

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Regulation of Histone Covalent Modifications During Yeast Apoptosis, Sung Hee Ahn-Upton

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Kh Domains on Brain Polyribosomes: FMRP and Nova in Translational Regulation, Claire Elizabeth Fraser

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The Role of Microglia in the Effects of Steroid Hormones on Brain Inflammation, Andres C. Gottfried-Blackmore

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The Role of Pot1 in Telomere Protection and Maintenance, Dirk Hockemeyer

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Comparative Studies of Processivity Clamp Loader ATP Site Function., Aaron M. Johnson

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Insect Host Seeking: Investigations into the Molecular Mechanisms of Chemosensation, Walton D. Jones

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The Role of Histone H2B Ubiquitylation and its Related Factors in Transcriptional Regulation in Mammalian Cells, Jaehoon Kim

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A Search for the Counter-Immune Mechanisms of Mycobacterium Tuberculosis, Meghan Alida Kirksey

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Energy Homeostasis During Fasting and Fed States: Foxa2 Regulates Hepatic Amino Acid Uptake, Vivian M. Lee

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Haplotype-Based Association Studies: Approaches to Current Challenges, Mark A. Levenstien

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Chronic Stress Effects on Prefrontal Cortical Structure and Function, Conor Liston

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The Role of Activation-Induced Cytidine Deaminase in Antibody Diversification and B Cell Malignancies, Eleonora Market

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The Multifunctional Capsid Gene of Hepatitis C Virus, Laura Katherine McMullan

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A Map of Transcription Factor Expression in Neuronal Precursors of the Chicken and Mouse Embryonic Cerebellum, Daniver Morales

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Genetic and Biochemical Analyses of the Flaviviridae Capsid Proteins, Catherine Lucy Murray

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A Structural Basis for Host Cytoskeletal Disruption and Virulence by Yersinia Protein Kinase A, Gerd Prehna

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Molecular Regulation of Hair Follicle Morphogenesis, Horace Rhee

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From Naturally Occurring Tumor Immunity to Supernatural T Cells: Isolation and Characterization of a Murine T Cell Receptor Specific for Human Breast and Ovarian Tumor Antigen Cdr2, Bianca D. Santomasso

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Autophagy Delivers Viral Antigens for MHC Class II Presentation and is Regulated by Viral Infection, Dorothee Schmid

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Death by Frustration: How Defects in Cell Differentiation Trigger Apoptosis, Ann H. Tang

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Targeted Disruption of Lynx2 Reveals Distinct Functions for Lynx Homologues in Learning and Behavior, Ayse Begum Tekinay

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Dissecting the Entry Pathways of Hepatitis C and Bovine Viral Diarrhea Viruses, Donna M. Tscherne

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Genetic and Molecular Characterization of Programmed Cell Death in the C.elegans Tail-Spike Cell, Carine Waase-Maurer

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Characterization and Functional Analysis of Astrotactin 2 Reveals a Role for Endocytosis in Glial-guided Neuronal Migration, Perrin Megan Wilson

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Role of Laminins in the Development of the Peripheral Nervous System, Wei-Ming Yu

2006

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TMEM27: A Cleaved and Shed Plasma Membrane Protein That Stimulates Pancreatic Beta Cell Proliferation, Pinar Akpinar

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Integration of Light and Temperature in the Regulation of Circadian Gene Expression in Drosophila, Catharine E. Boothroyd

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Telomere Structure and Shortening in Telomerase-Deficient Trypanosoma brucei: Implications for Anitgenic Variation, Oliver Dreesen

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The Role of Drosophila Odorant Receptors in Odor Coding, Elane Fishilevich

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NKAINs: A Novel Family of Membrane Proteins that Interact with the Na, K-ATPase and Affect Membrane Excitability, Svetlana Gorokhova

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Role of Laminin gamma 1 in Cortical Development, Veronique Haegeli

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Self-Renewal Requirements of Human Embryonic Stem Cells and Their Engraftment Potential in Mouse Blastocysts, Daylon Jefferson James

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Dendritic Cells Mediate the Dual Effects of IFN alpha/beta in HCV Immunity, Randy Longman

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Glyoxylate Metabolism in Mycobacterium smegmatis, Lubomir Nikolaev Merkov

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Exploring the Biophysical Properties of Domains Within Multi-Domain Proteins, Vasant Muralidharan

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Immunologic Memory to Polysaccharide Antigens, Tetyana V. Obukhanych

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The Roles of daf-6 and Cell-Cell Interactions in Sensory Organ Morphogenesis, Elliot A. Perens

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Studies on the Histone Methyltransferase G9a, Srihari Cidambi Sampath

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Control of Chromosome Segregation by the Aurora B Complex, Srinath Cidambi Sampath

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A Molecular Dissection of the Ventromedial Hypothalamic Nucleus, Jeremy P. Segal

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The Dual Role of OCA-B in B Cell Development and Signaling, Rachael Siegel

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Structural Analysis of an RNA Polymerase Sigma Factor and Its Anti-sigma: sigma28/FLGM, Margareta K. Sörenson

2005

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Exploring the Early Events in the HIV-1 Life Cycle: From Post-Entry Restriction to Nuclear Import, Tshaka J. Cunningham

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Genetic and Biochemical Studies on Protein Phosphorylation in the Circadian Clock of Drosophila Melanogaster, Saul Kivimae

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The Role of the Glyoxylate Cycle in the Pathogenesis of Mycobacterium tuberculosis, Ernesto Javier Munoz-Elias

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Myosin-Like Proteins in S. cerevisiae: Multifunctional, Structural Components of the Nuclear Envelope, Mario Niepel

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The Structural and Functional Analysis of a Voltage-Dependent Potassium Channel, Vanessa Ruta