Student Theses and Dissertations
The Rockefeller University has awarded over one thousand Ph.D’s since 1959. This collection contains theses beginning with the graduating class of 2006. Earlier theses are added by request or as permission to digitize is received. For more information visit the FAQ page.
2017
Isopeptide and Ester Bond Ubiquitination Regulate Degradation of the Human Dopamine Receptor 4, Jennifer C. Peeler
Single Molecule Ligand Binding Studies on CCR5 by Fluorescence Cross-Correlation Spectroscopy, Carlos Rico
Compromising the 20S Proteasome Activates a Quality Control Pathway to Mitigate Proteotoxic Stress, Irit Shachrai
IR Laser-Induced Gene Expression for Tracking Development of Single Embryonic Neurons and Glia in C. Elegans, Anupriya Singhal
Lysin Based Antimicrobial Peptides Against Acinetobacter Baumannii, Mya Thandar
Separate Roles of FAN1 and Fanconi Anemia Proteins in DNA Interstrand Crosslink Repair and Human Disease, Supawat Thongthip
A Comparative Study of Sensory Neuron Synaptic Activity and the Role of Presynaptic Diversity, Specificity, and Regulation in Caenorhabitis Elegans, Donovan Ventimiglia
Regulated Recruitment of the Chromosomal Passenger Complex to Chromatin and Microtubules Promotes Accurate Cell Division, Michael Wheelock
High Throughput Detection of Pseudouridine: Caveats, Conundrums, and a Case for Open Science, Maryam Zaringhalam
2016
Escherichia Coli as a New Platform for the Study of Phosphoinositides, Sergio Botero
Studies Towards the Discovery of Novel Natural Products Through Functional Analysis of Environmental DNA-Encoded Type II Polyketide Synthases, Debjani Chakraborty
The Genetics Of Mosquito Heat-Seeking Behavior, Román A. Corfas
Molecular Basis of Mechanosensitivity, Josefina Ines del Marmol
Investigating the Role of Muscleblind-Like 1 in the Suppression of Breast Cancer Progression, Lisa Fish
Nanobody-Based Interactomic Studies of Single Transcripts During mRNA Maturation, Peter C. Fridy
A Census of Human RNA-Binding Proteins, Stefanie Gerstberger
Selection Dynamics in the Germinal Center During Antibody Affinity Maturation, Alexander Gitlin
Characterization of Skin Immune Reactions Induced by the Contact Sensitizer Diphencyprone in Healthy Volunteers and Metastatic Melanoma Patients, Nicholas Gulati
Plasticity of the Nuclear Pore Complex Revealed With Proteomics, Zhanna Hakhverdyan
Dynamics of HIV-1 Infection and Therapy In Vivo, Joshua Abraham Horwitz
Natural Products From Functional Screening of Soil Metagenomic Libraries, Hala Iqbal
CPISPR-CAS: From a Prokaryotic Immune System to a Gene Editing Tool, Wenyan Jiang
Aversive Olfactory Imprinting in Caenorhabditis Elegans, Xin Jin
Regulatory Architecture of Non-Apoptotic Cell Death Program in C. Elegans, Maxime Jeremie Kinet
Extracellular Metabolic Energetics Can Promote Cancer Progression, Jia Min Loo
Qualitative and Quantitative Regulation of the Leptin Gene in vivo, Yi-Hsueh Lu
Paleovirological Analyses of Endogenous Retroviruses and Host Innate Immune Effectors, Daniel Blanco Melo
Tracking the In Vivo Dynamics of Antigenic Variation in the African Trypanosome, Monica R. Mugnier
Genetic Dissection of Neural Circuits Underlying Value Based Decision Making, Hirofumi Nakayama
Characterization of Mechanisms That Mediate Cancer Metastatic Colonization, Alexander Huan Nguyen
Structural and Functional Characterization of SPOA Domains in Salmonella Typhimurium Type III Secretion Systems, Ryan Q. Notti
Regulation of the Anaphase-Promoting Complex Examined at the Single Cell Level, Andrej Ondracka
Retrograde Activation of a Somatic Transcriptional Program Regulates Distal Axon Degeneration, Jason Pitts
Metabolic Regulation of Gene Expression through Differential Histone Acylation: The Regulation and Function of Histone Crotonylation, Benjamin R. Sabari
Protein Regulators of Phosphoinositides as Promoters of Cancer Metastasis, Caitlin Anne Sengelaub
Analysis of Hepatocyte Secretion Pathways: A Case Study on Hepatic Apolipoproteins, Serum Albumin, and Hepatitis C Virus, Constantin N. Takacs
Reconstitution and Mechanistic Studies on the Staphylococcal agr Quorum Sensing Circuit, Boyuan Wang
Chemical Tools for Exploring IFITM3 S-Palmitoylation and Mechanism, Xiaoqiu Yuan
2015
Why Mosquitoes Bite Some People More Than Others: Metabolic Correlates of Human Attraction in AEDES AEGYPTI, Lindsay Lee Bellani
Mechanism of Action of ING4 as a Transcriptional Coactivator of p53, Jabez Bok
Metagenomics-Based Tryptophan Dimer Natural Product Discovery and Development Pipeline, Fang-Yuan Chang
Mechanisms of Olfactory Plasticity in Caenorhabditis Elegans, Christine Cho
Synapse Formation in the Zebrafish Lateral Line, Eliot Dow
Normalization Among Heterogeneous Population Confers Stimulus Discriminability on the Macaque Face Patch Neurons, Akinori F. Ebihara
Effects of Temporal and Spatial Context Within the Macaque Face-Processing System, Clark Andrew Fisher
Therapeutic Uses of Broadly Neutralizing Anti-HIV-1 Antibodies in Humanized Mice, Ariel Halper-Stromberg
Studies on the Maturation of Secreted Quorum Sensing Peptides That Regulates S. Aureus Virulence, Jeffrey Grant Johnson
Investigating Mechanisms of Telomere End-Protection, Shaheen Kabir
The Effect of Chronic Hypertension on Neuropathology in the TGSWDI Mouse Model of Alzheimer's Disease, Anna Kruyer
A Mechanism for Spatial Orientation Based on Sensory Adaptation in Caenorhabditis Elegans, Johannes Larsch
Identification of TMEM2 as a SOX4 Transcriptional Target Involved in Breast Cancer Metastasis, Hyeseung Lee
Hair Bundles of a Jawless Vertebrate Employ Tetrapod-Like Tuned Mechanical Amplification, Katherine J. Leitch
A Genomic Portrait of Hepatitis C Virus and MicroRNA-122, Joseph M. Luna
Functional Dissection of Brainstem Circuitry, Alexander Ryan Nectow
A Reductionist Approach to Modeling Human Corticogenesis, Mohammad Zeeshan Ozair
A Reductionist Approach to Modeling Human Corticogenesis, Mohammad Zeeshan Ozair
Specialized Signals for Spatial Attention in the Ventral and Dorsal Visual Streams, Pablo Polosecki
Characterization of Bacterial Metabolites Involved in Host Pathogen Resistance, Kavita J. Rangan
Molecular Determinants of Tumor Re-Initiation in Breast Cancer, Jason Barzel Ross
Mechanical Control of Sensory Hair-Bundle Function, Joshua D. Salvi
Activity Based Profiling: New Insights into Metabolic Homeostasis, Keith Tan
Xenopus DPPA2 is a Direct Inhibitor of Microtubule Polymerization Required for Nuclear Assembly, John Zhao Xue
Neural Circuit Dependence of Acute and Subacute Nociception in C. Elegans, Yifan Xu
A New Role for Beta-Amyloid in Alzheimer's Disease: Initiation of Thrombotic and Inflammatory Processes Via Coagulation Factor XII and Fibrinogen, Daria Zamolodchikov
Components of the Ubiquitin Proteasome System are Required for the Nonapoptotic Death of the C. Elegans Linker Cell, Jennifer Zuckerman Malin
2014
Abdominal-B Neurons Control Drosophila Virgin Female Receptivity, Jennifer J. Bussell
Stochastic Activation of Enhancers in the Innate Immune Response by the Histone Demethylase JMJD2D, Rohit Chandwani
Coordinating Stem Cell Behavior in the Hair Follicle, Chiung-Ying Chang
Taming a Potent Mutator: Identification and Characterization of Novel Mechanisms of Regulating Antibody Diversification in B-Lymphocytes, Rebecca Kyle Delker
Genome-Wide Characterization of the Effects of Nucleic Acid Modifying Enzymes: Cytidine Deaminases and DNA Methylation, Eric Luke Fritz
Mutations in a Mechanosensitive Channel Enable Intravascular Metaststic Cell Survival, Paul William Furlow
Studies of a Novel Phage Lytic Enzyme, PlySs2, Daniel B. Gilmer
Transcriptome-Wide Characterization of APOBEC1-Catalyzed RNA Editing Events in Macrophages, Claire Ellen Hamilton
Forces Generated by Cell Intercalculation Tow Epidermal Sheets in Mammalian Tissue Morphogenesis, Evan Heller
Chromatin Control of the Antiviral Response to Influenza, Jessica Sook Yuin Ho
Identification of a Functional Hotspot on Ubiquitin Required for Stimulation of Methyltransferase Activity on Chromatin, Matthew Thomas Holt
High Resolution Maps of the Vasculature of An Entire Organ, Oppenheim N. Jacob
The Structural and Biochemical Characterization of Salmonella Host Specificity Determinant Gifsy-2 Gene E, Amanda C. Kohler
Functional and Structural Studies of the Human Voltage-Gated Proton Channel, James Anthony Letts
The Neuropeptide Regulation of Host-Seeking Behavior in Aedes Aegypti Mosquitoes, Jeff Liesch
RNA Deregulation in Metastatic Breast Cancer, Christina Beate Marney
Identification of a Microrna Network that Regulates Melanoma Metastasis and Angiogenesis by Targeting Apoe, Nora Pencheva
Causes and Consequences of Genetic Robustness and Fragility in HIV-1 Proteins, Suzannah J. Rihn
The Origin of Multiple Sclerosis Revisited: The Case for a Soluble Toxin, Kareem Rashid Rumah
HIV Specific B Cell Response in Patients With Broadly Neutralizing Serum Activity, Johannes F. Scheid
Split Inteins: From Mechanistic Studies to Novel Protein Engineering Technologies, Neel H. Shah
Exploration of Cell Cycle-Specific Essential Gene Functions in the Microbial Plant Chlamydomonas Reinhardtii, Frej Tulin
Mechanism and Evolutionary Origins of HIV-1 Virion Entrapment by Tetherin, Siddarth Venkatesh
2013
Decoding 5HMC as an Active Chromatin Mark in the Brain and its Link to Rett Syndrome, Pinar Ayata
Cannabinoid CB1R Receptor Mediates Metabolic Syndrome in Models of Circadian and Glucocorticoid Dysregulation, Nicole Bowles
Telomere-Driven Tetraploidy and its Relevance to Cancer, Teresa Davoli
Analysis of Small Molecule Inhibitors Aimed at Bacterial Virulence, Paul Daniel Dossa
Mechanism of Translational Control by the Fragile X Mental Retardation Protein and Creation of the FMRP CTAG Mouse, Sarah Van Driesche
RNA Dynamics in T Cell Activation, Emily Conn Gantman
Application of Genetically-Encoded Photoactivatable Crosslinkers to Map Ligand-Binding Sites on G Protein-Coupled Receptors, Amy Grunbeck
Novel Molecules from Environmental DNA-Derived Type II Polyketide Biosynthetic Gene Clusters, Ryan W. King
Examining the Regulation of Cell Division by the Spindle Assembly Checkpoint, Maria Maldonado