Student Theses and Dissertations
The Rockefeller University has awarded over one thousand Ph.D’s since 1959. This collection contains theses beginning with the graduating class of 2006. Earlier theses are added by request or as permission to digitize is received. For more information visit the FAQ page.
2008
Conditional Protein Alleles and Regulation of Bacterial Transcription: A Thesis in Two Acts, Edmund Ching Schwartz
Cellular and Molecular Mechanisms Underlying Leptin’s Metabolic Effects, Amandeep Singh
Crystal Structure and Mechanism of Lysine Specific Demethylase-1, Pete G. Stravropoulos
The Apollo Nuclease Binds To TRF2 and Protects, Megan van Overbeek
Dendritic Cells in Normal and Inflamed Human Skin, Lisa C. Zaba
Identification of Loss of Specific FMRP-RNA Interactions as a Cause of Fragile X Syndrome, Julie B. Zang
2007
A New Type of Programmed Cell Death in C. Elegans, Mary C. Abraham
Regulation of Histone Covalent Modifications During Yeast Apoptosis, Sung Hee Ahn-Upton
Kh Domains on Brain Polyribosomes: FMRP and Nova in Translational Regulation, Claire Elizabeth Fraser
The Role of Microglia in the Effects of Steroid Hormones on Brain Inflammation, Andres C. Gottfried-Blackmore
The Role of Pot1 in Telomere Protection and Maintenance, Dirk Hockemeyer
Comparative Studies of Processivity Clamp Loader ATP Site Function., Aaron M. Johnson
Insect Host Seeking: Investigations into the Molecular Mechanisms of Chemosensation, Walton D. Jones
The Role of Histone H2B Ubiquitylation and its Related Factors in Transcriptional Regulation in Mammalian Cells, Jaehoon Kim
A Search for the Counter-Immune Mechanisms of Mycobacterium Tuberculosis, Meghan Alida Kirksey
Energy Homeostasis During Fasting and Fed States: Foxa2 Regulates Hepatic Amino Acid Uptake, Vivian M. Lee
Haplotype-Based Association Studies: Approaches to Current Challenges, Mark A. Levenstien
Chronic Stress Effects on Prefrontal Cortical Structure and Function, Conor Liston
A Genetic-Proteomic Approach to Identify Cellular Components that Interact with HIV-1, Yang Luo
The Role of Activation-Induced Cytidine Deaminase in Antibody Diversification and B Cell Malignancies, Eleonora Market
The Multifunctional Capsid Gene of Hepatitis C Virus, Laura Katherine McMullan
A Map of Transcription Factor Expression in Neuronal Precursors of the Chicken and Mouse Embryonic Cerebellum, Daniver Morales
Genetic and Biochemical Analyses of the Flaviviridae Capsid Proteins, Catherine Lucy Murray
A Structural Basis for Host Cytoskeletal Disruption and Virulence by Yersinia Protein Kinase A, Gerd Prehna
Molecular Regulation of Hair Follicle Morphogenesis, Horace Rhee
From Naturally Occurring Tumor Immunity to Supernatural T Cells: Isolation and Characterization of a Murine T Cell Receptor Specific for Human Breast and Ovarian Tumor Antigen Cdr2, Bianca D. Santomasso
Autophagy Delivers Viral Antigens for MHC Class II Presentation and is Regulated by Viral Infection, Dorothee Schmid
Death by Frustration: How Defects in Cell Differentiation Trigger Apoptosis, Ann H. Tang
Targeted Disruption of Lynx2 Reveals Distinct Functions for Lynx Homologues in Learning and Behavior, Ayse Begum Tekinay
Dissecting the Entry Pathways of Hepatitis C and Bovine Viral Diarrhea Viruses, Donna M. Tscherne
Genetic and Molecular Characterization of Programmed Cell Death in the C.elegans Tail-Spike Cell, Carine Waase-Maurer
Characterization and Functional Analysis of Astrotactin 2 Reveals a Role for Endocytosis in Glial-guided Neuronal Migration, Perrin Megan Wilson
Role of Laminins in the Development of the Peripheral Nervous System, Wei-Ming Yu
2006
TMEM27: A Cleaved and Shed Plasma Membrane Protein That Stimulates Pancreatic Beta Cell Proliferation, Pinar Akpinar
Integration of Light and Temperature in the Regulation of Circadian Gene Expression in Drosophila, Catharine E. Boothroyd
Telomere Structure and Shortening in Telomerase-Deficient Trypanosoma brucei: Implications for Anitgenic Variation, Oliver Dreesen
The Role of Drosophila Odorant Receptors in Odor Coding, Elane Fishilevich
NKAINs: A Novel Family of Membrane Proteins that Interact with the Na, K-ATPase and Affect Membrane Excitability, Svetlana Gorokhova
Role of Laminin gamma 1 in Cortical Development, Veronique Haegeli
Self-Renewal Requirements of Human Embryonic Stem Cells and Their Engraftment Potential in Mouse Blastocysts, Daylon Jefferson James
Dendritic Cells Mediate the Dual Effects of IFN alpha/beta in HCV Immunity, Randy Longman
Microarray Analysis Identifies Novel Cholesterol Regulated Genes, Including Pcsk9 Which Regulates LDL Receptor Function and LDL Cholesterol Levels, Kara Noelle Maxwell
Glyoxylate Metabolism in Mycobacterium smegmatis, Lubomir Nikolaev Merkov
Exploring the Biophysical Properties of Domains Within Multi-Domain Proteins, Vasant Muralidharan
Immunologic Memory to Polysaccharide Antigens, Tetyana V. Obukhanych
The Roles of daf-6 and Cell-Cell Interactions in Sensory Organ Morphogenesis, Elliot A. Perens
Studies on the Histone Methyltransferase G9a, Srihari Cidambi Sampath
Control of Chromosome Segregation by the Aurora B Complex, Srinath Cidambi Sampath
A Molecular Dissection of the Ventromedial Hypothalamic Nucleus, Jeremy P. Segal
The Dual Role of OCA-B in B Cell Development and Signaling, Rachael Siegel
Structural Analysis of an RNA Polymerase Sigma Factor and Its Anti-sigma: sigma28/FLGM, Margareta K. Sörenson
2005
Exploring the Early Events in the HIV-1 Life Cycle: From Post-Entry Restriction to Nuclear Import, Tshaka J. Cunningham
Genetic and Biochemical Studies on Protein Phosphorylation in the Circadian Clock of Drosophila Melanogaster, Saul Kivimae
The Role of the Glyoxylate Cycle in the Pathogenesis of Mycobacterium tuberculosis, Ernesto Javier Munoz-Elias
Myosin-Like Proteins in S. cerevisiae: Multifunctional, Structural Components of the Nuclear Envelope, Mario Niepel
The Structural and Functional Analysis of a Voltage-Dependent Potassium Channel, Vanessa Ruta
Comparative Analysis of Alternative Splicing in Homo sapiens, Mus musculus and Rattus norvegicus Transcriptomes, Bahar Taneri
2004
Site and Mechanism of Leptin's Antisteatotic and Insulin Sensitizing Actions in Lipodystrophic Liver, Esra Asilmaz
Using Microscopy to Examine Mechanisms of Cell Division, Lily Copenagle
Attenuated Salmonella Typhimurium Can Be Used to Transduce Human Dendritic Cells Towards Vaccination Against HIV-1, Deborah Gurner
Differential Screening in Immunodeficient Mice Reveals Bacterial Enzymes With Unexpected Roles in Host-Pathogen Interactions, Katherine B. Hisert
Roles for the E3 Ligase Itch in Immune Response Modulation, Sukhvinder Kaur Sahota
Molecular Basis of Vertebrate Embryonic Migration, Paris A. Skourides
A Novel Subfamily of Three StAR-Related Lipid Transfer Proteins That Are Differentially-Regulated and Function in Intracellular Cholesterol Metabolism, Raymond E. Soccio
Resonant Detection of Nano to Microscopic Objects Using Whispering Gallery Modes, Frank Vollmer
Functional analyses of hTel2 and TRF2 deltaB: Insights Into the Role of a New DNA Damage Pathway and Homologous Recombination in Mammalian Telomere Function, Richard Chih-Chien Wang
2003
Measurement of the Diffractive Structure Function of the Antiproton in Proton-Antiproton Collisions at √ s = 1800 and 630 GeV, Kenichi Hatakeyama
Isolation and Characterization of Estrogen Receptor- Interacting Proteins, Yun Kyoung Kang
RCK Domain Model of Calcium Activation in BK Channels, Alexander R. Pico
Subcellular Localization and Activity of the Multidrug Resistance Protein 1, Asha Rajagopal
Identification and Characterization of the DNA Damage Response Function of Human Rif1 and a Search For Human Rap1 Interacting Factors, Joshua Silverman
Protein Semi-Synthesis in Vivo, Izabela Giriat Stankiewicz
Functional Roles of Nova in RNA Metabolism, Giovanni Stefani
2002
Transcription, Editing, and Switching of Antibody Genes, Rafael Casellas
Biogenesis and Traffic of the Potassium Channel, Natalie de Souza
Nova Regulation of Alternative Splicing in the CNS, B Kate Dredge
Site-Specific Incorporation of Biochemical and Biophysical Probes into Proteins Using Expressed Protein Ligation, Mande Holford
Targeting Receptor-Histidine Kinase Signaling in Staphylococcus Aureus, Gholson J. Lyon
Stress and Hippocampal Plasticity, Kara Pham
Mapping Genes for Complex Traits: Obesity, Diabetes, Hypertension, and Dyslipidemia on the Pacific Island of Kosrae, Dvora Shmulewitz
ZIPRO1: Fine Tuning Proliferation in Discrete Cell Populations, Christopher Wynder
Structural Studies of DNA Replication Proteins by X-Ray Crystallography and Molecular Dynamics, Yanxiang Zhao
2001
Emerging Auditory Selectivity in the Caudomedial Neostriatum of the Zebra Finch Songbird, Caroline Wan-Yin Ang
Mechanisms of TRAFSignaling, Joseph R. Arron
Impact of Thymectomy on the Peripheral T Cell Pool in the Context of SIV Infection, Sarah Tuttleton Arron
Molecular Anatomy of a Living Nerve Terminal: Actin and Synapsin in the Synaptic Vesicle Cycle, Ona E. Bloom
Genetic Studies on the Circadian Clock in the Model Organism Drosophila Melanogaster, Sebastian Martinek
Antigenic Variation and Telomere Structure in Trypanosoma brucei, Jorge Luis Munoz Jordan
Interactions between Nova and brPTB Proteins in Alternative Splicing and Nuclear Localization, Alexandros Demetrios Polydorides
Genetic and Molecular Analysis of Islet-and Liver-Enriched Transcription Factors in Metabolism and Development, David Quan Shih
Functional Analysis of the Human Telomeric Protein TRF2, Agata Smogorzewska
2000
Dynamics of DNA Breathing and Folding for Molecular Recognition and Computation, Gregoire Bonnet
Structure-Function Studies on Human Epithelial Cystic Fibrosis Chloride Channels Expressed in Xenopus Laevis Oocytes, Laszlo Csanady
An Alternative View of the Templates and Functions of RNA Polymerase II, Julija Filipovska
A Niche for Adult Neurogenesis: Analysis of BMP Signaling and Transcriptional Profiles of Adult Subventricular Zone Cells, Daniel A. Lim
Information Encoding by Individual Neurons and Groups of Neurons in the Primary Visual Cortex, Daniel Salo Reich
The Brain Invaders: Widespread Neuronal Dispersion in Developing and Adult Mammalian Brain, Hynek Wichterle