Student Theses and Dissertations

 

The Rockefeller University has awarded over one thousand Ph.D’s since 1959. This collection contains theses beginning with the graduating class of 2006. Earlier theses are added by request or as permission to digitize is received. For more information visit the FAQ page.

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2010

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Reconstitution and Characterization of Human Endogenous Retrovirus-K, Young Nam Lee

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Mechanisms for Maintaining Cell Identity in C.elegans Olfactory Neurons, Bluma J. Lesch

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Mitotic Exit Control in Budding Yeast: Regulators and Dynamics, Ying Lu

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Mechanistic Insights into the Stimulation of Dot1L-Mediated Methylation of Histone H3 by Semisynthetically Ubiquitylated Histone H2b, Robert Kendall McGinty

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Dynamic and Integrative Properties of the Primary Visual Cortex, Justin N. J. McManus

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Structural and Molecular Correlates of Individual Differences in Anxiety Behavior and the Stress Response, Melinda Miller

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Dissecting the Contribution of the Carboxyl-Terminal Domain and Tail of HIV-1 Integrase to Viral Dynamics and Enzymatic Function, Kevin Dominic Mohammed

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Synaptic Specificity in the Zebrafish Lateral Line, Aaron Nagiel

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Biochemical and Structural Analysis of the Nucleoporin Nup214 and its Involvement in mRNA Export, Johanna Napetschnig

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Localization and Function Of RNA Interference in the Cerebral Cortex, John T. G. Pena

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Regulation of Surface Proteins Assembly on the Wall of Gram-Positive Bacteria, Assaf Raz

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Characterization of the Functional Role of the Intracellular Cholesterol Transporter StARD4 in Knockout Mice, and Investigation of Epigenetic Modulation of ApoA-I Transcription, Joshua Riegelhaupt

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Regulation of Anaphase Promoting Complex Coactivators, Jonathan Robbins

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Identification and Characterization of APOBEC1 mRNA Editing Targets: A Transcriptomics Approach, Brad Randall Rosenberg

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Mechanisms Of Presynaptic CaV2 Calcium Channel Localization In Caenorhabditis Elegans, Yasunori Saheki

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Lipid Chemistry and Mechanical State of the Membrane Modulate Ion Channel Function, Daniel Schmidt

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The Impact of Host Factors on Retroviral Evolution and the Identification of a Novel Receptor That Was Used by an Ancient Primate Retrovirus, Steven J. Soll

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Regulation of Chromosome Segregation by the Chromosomal Passenger Complex, Boo Shan Tseng

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Characterization of a Novel Chromatin‐Induced Mechanism that Couples Microtubule Disassembly and Nuclear Re‐Formation, Eileen Madeleine Woo

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Role of Ubiquitin and Ubiquitin Ligases in Retroviral Budding, Maria Zhadina

2009

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Glia Are Required For Sensory Neuron Morphology And Function In Caenorhabditis elegans, Taulant Bacaj

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Studies of G-Protein Coupled Receptors Incorporated Into a Novel, Nanoscale, Membrane-Mimetic System, Sourabh Banerjee

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Analysis of Cellular Factors Involved in Adeno-Associated Virus Type 2 Entry, Cameron Dale Bess

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Transcriptional Regulation Of Adipocyte Function, Kivanc Birsoy

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The Role Of Adult Stem Cells And Tumor Necrosis Factor In Peripheral Neuropathy, Prabhjot Singh Dhadialla

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Characterization of a Novel 53BP1-Dependent Mechanism that Promotes Non-Homologous End Joining of Deprotected Telomeres by Increasing Chromatin Mobility, Nadya Dimitrova

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Cell Size Control And Asymmetric Cell Fates In Start Of The Saccharomyces cerevisiae Cell Cycle, Talia, Stefano Di

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Regulation of the Heterochromatin Protein 1 by Phosphorylation of Histone H3 and the HP1 Hinge Domain, Holger Dormann

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Peak Mitotic Cyclin Permits Mitotic Exit, Benjamin Drapkin

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Regulated Histone H3 Proteolysis During Mouse Embryonic Stem Cell Differentiation, Elizabeth M. Duncan

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Novel Interactions of the Hormone Leptin Revealed by PET Imaging in Rodents and Rhesus Macaques, Robert Richard Flavell

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A Model of the Production of Spontaneous Otoacoustic Emissions in the Tokay Gecko, Michael Gelfand

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Mechanism of Signal Transduction By The Staphylococcus Aureus Quorum Sensing Receptor AGRC, Elizabeth A. George Cisar

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Perceptual Learning Of Object Shape, Doruk Golcu

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Population Dynamics In A Model Closed Ecosystem, Doeke Romke Hekstra

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Synaptic Protein Profiling in the Mammalian Brain, Elizabeth Heller

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Mechanistic and Physiological Studies of the Insulin-Dependent Regulation of FOXA2, Jessica Jean Howell

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Architecture of a Coat for the Nuclear Pore Membrane, Kuo-Chiang Hsia

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Biophysical Characterization of Structure and Dynamics of Nuclear Pore Complex Components, Martin Kampmann

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Transfer Properties of the Hair Cell-Afferent Fiber Synapse, Erica C. Keen

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The Neural Circuitry Of Social Behavior In C. elegans, Evan Z. Macosko

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The Manipulation Of Apical Dendritic Plasticity And The Consequences For The Effects of Chronic Stress, Trudy McCall

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Novel Roles for the Tissue Plasminogen Activator System in the Development of Fetal Alcohol Syndrome and the Regulation of Contextual Learning After Stress, Melissa Noel-Castro

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Specification And Function Of Early Hair Follicle Stem Cells, Jonathan Nowak

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Fibrin Formation and Dissolution in the Progression of Amyloid-Beta Pathology in Alzheimer's Disease, Justin Paul

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Perceptual Learning, Long-Range Horizontal Connections And Top-Down Influences In Primary Visual Cortex, Valentin Piëch

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Dissecting the Development and Function of C. elegans Glia with Mutations of the mls-2 and vab-3 Genes, Yoshimura Satoshi

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Regulation of Apoptosis by XIAP Ubiquitin- Ligase Activity, Andrew James Schile

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Hierarchy and CIS-Regulation in Drosophila Segmentation: Rules for Pattern Formation and Clues to Evolution, Mark David Schroeder

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Regulation of Gene Expression in Trypanosoma brucei, Tim Nicolai Siegel

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The Role and Fate of Branch Site-U2 snRNA Interaction During Pre-mRNA Splicing, Duncan Smith

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Physiological Effects of Estradiol in the Mouse Hippocampal Formation, Joanna L. Spencer

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Of Mice and Men: Studying Innate and Adaptive Immunity Against the Epstein-Barr Virus, Till Strowig

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Regulation of Immunoglobulin Gene Diversification By Noncoding RNA's, Grace Teng

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Biochemical Analysis of the Protein-Protein Interactions Involved in Karyopherin-Mediated Transport Across the Nuclear Pore Complex, Jaclyn Tetenbaum-Novatt

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Dissecting the Functions of Classical Cadherins in Skin, Christopher Tinkle

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Structural Studies of Three Factors That Affect the Prokaryotic Transcription Cycle; Microcin J25, LAMBDA Q and T4 GP33, Kelly-Anne Fisi Twist

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An In Vivo Characterization of the Functional Role of Two Novel Genes: StARD5 and ADAM11, Marc Paul Waase

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Circuit Dynamics of Adult Visual Cortex, Homare Yamahachi

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Biochemical and Genetic Studies of Beclin 1 Function in Autophagy, Yun Zhong

2008

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Tuning of the Active Hair Bundle, Omar Ahmad

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Cracking the Odor Code: Molecular and Cellular Deconstruction of the Olfactory Circuit of Drosophila Larvae, Kenta Asahina

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The Differential Contribution of Striatonigral and Striatopallidal Neurons in Mediating Responses to Therapeutic Agents and Drugs of Abuse: A Dual Role for DARPP-32, Helen S. Bateup

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Proteomic, Bioinformatic and Functional Characterization of the Nuclear Pore Complex of the African Trypanosome, Jeffrey Allen DeGrasse

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The Hu Syndrome: At the Intersection of Cancer and Autoimmunity, Ilana J. DeLuca

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Further Insight into the Two Functions of Telomeres: Determining the Role of Tankyrase1 in Telomere Length Regulation and Tin2 in Telomere Protection, Jill Donigian

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Role of AID and microRNA-155 in c-myc-IgH Translocations, Yair Dorsett

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Discovery of the First Endogenous Gain of Function Mutation in Drosophila RAS1 as a Dominant Suppressor of Apoptosis, Christopher Gafuik

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Semi-Synthesis of the Transcription Factor SMAD2 Containing Caging Groups and Phosphoaminoacid Analogues, Michael Eric Hahn

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A Novel Phosphorylation Site in the Telomeric Protein TRF2 is Regulated by the ATR Kinase and Plays a Role in Relieving Replication Stress at the Telomere, Kristina Hoke

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Structural Analysis of Cycle Inhibiting Factor from Pathogenic Escherichia Coli, Yun-Yuan Hsu

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A Structural and Biochemical Analysis of the Drosophila Protein Period, Heather Anne King

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Structural and Computational Studies of RNA Polymerase, William J. Lane

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The Role of GDF-3 in Patterning the Early Embryo, Ariel Levine

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Visualizing Dendritic Cells In Vivo, Randall L. Lindquist

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Histone Modifications in Trypanosoma Brucei, Veena Mandava

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Dendritic Cell Regulation of Peripheral Tolerance in Polyclonal T Cell Repertoires, Revati F. Masilamani

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Dividing the Preplate: Characterization of Neuronal Subpopulations in the Early Murine Cerebral Cortex, Hilleary Botts Osheroff

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Small Molecules as Probes for Cell Division and Intracellular Transport, Ulf Peters

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Bioluminescence-Based High Precision Bacterial Growth Rate Measurements and Their Potential Application in Quantifying Deleterious Effects of High Mutation Rates, Sri Ram

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Conditional Protein Alleles and Regulation of Bacterial Transcription: A Thesis in Two Acts, Edmund Ching Schwartz

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Cellular and Molecular Mechanisms Underlying Leptin’s Metabolic Effects, Amandeep Singh

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Crystal Structure and Mechanism of Lysine Specific Demethylase-1, Pete G. Stravropoulos

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The Apollo Nuclease Binds To TRF2 and Protects, Megan van Overbeek

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Dendritic Cells in Normal and Inflamed Human Skin, Lisa C. Zaba

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Identification of Loss of Specific FMRP-RNA Interactions as a Cause of Fragile X Syndrome, Julie B. Zang

2007

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A New Type of Programmed Cell Death in C. Elegans, Mary C. Abraham

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Regulation of Histone Covalent Modifications During Yeast Apoptosis, Sung Hee Ahn-Upton

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Kh Domains on Brain Polyribosomes: FMRP and Nova in Translational Regulation, Claire Elizabeth Fraser

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The Role of Microglia in the Effects of Steroid Hormones on Brain Inflammation, Andres C. Gottfried-Blackmore

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The Role of Pot1 in Telomere Protection and Maintenance, Dirk Hockemeyer

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Comparative Studies of Processivity Clamp Loader ATP Site Function., Aaron M. Johnson

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Insect Host Seeking: Investigations into the Molecular Mechanisms of Chemosensation, Walton D. Jones

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The Role of Histone H2B Ubiquitylation and its Related Factors in Transcriptional Regulation in Mammalian Cells, Jaehoon Kim

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A Search for the Counter-Immune Mechanisms of Mycobacterium Tuberculosis, Meghan Alida Kirksey

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Energy Homeostasis During Fasting and Fed States: Foxa2 Regulates Hepatic Amino Acid Uptake, Vivian M. Lee

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Haplotype-Based Association Studies: Approaches to Current Challenges, Mark A. Levenstien

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Chronic Stress Effects on Prefrontal Cortical Structure and Function, Conor Liston

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A Genetic-Proteomic Approach to Identify Cellular Components that Interact with HIV-1, Yang Luo

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The Role of Activation-Induced Cytidine Deaminase in Antibody Diversification and B Cell Malignancies, Eleonora Market