Student Theses and Dissertations
The Rockefeller University has awarded over one thousand Ph.D’s since 1959. This collection contains theses beginning with the graduating class of 2006. Earlier theses are added by request or as permission to digitize is received. For more information visit the FAQ page.
2018
Characterizing Human Transfer RNAS by Hydro-TRNASEQ and PAR-CLIP, Tasos Gogakos
Investigating Genetic (IN)Compatibility Between Temperate Phages and CRISPR-CAS Systems in Staphylococcus Aureus, Gregory W. Goldberg
Modeling Alzheimer's Disease in Induced Pluripotent Stem Cells, Andrew Gregg
The Characterization of a Novel Complex Implicated in the Initiation of Apoptosis, Thomas Hsiao
Identification and Characterization of Hells-CDCA7, a Nucleosome Remodeling Complex Required for Mitotic Chromosome Structure, Christopher Jenness
A Role for PI31-Mediated Proteasome Regulation in Proteostasis and Neuronal Health, Sandra Jones
Cell Type Specific Roles of Serotonin Receptor 4 in the Hippocampus and Neocortex in Emotion and Cognition, Remzi Karayol
Components Required for the Death and Degradation of the Linker Cell in C. Elegans, Lena Marlise Kutscher
Robustness Enhancement of Sensory Transduction by Hair Bundles, Andrew Robert Milewski
In Search of Generic Properties of Evolved Systems: From Elasticity of Proteins to Structure of Metabolic Networks, Michael Robert Mitchell
A High-Throughput Approach to Uncover Novel Roles of APOBEC2, a Functional Orphan of the AID/APOBEC Family, Linda Molla
Characterization and Reconstitution of S-Palmitoylated IFITM3 Antiviral Activity, Avital Percher
Surface Coat Replacement Dynamics and Antigen Glycosylation in T. Brucei Influence Evasion of the Host Antibody Response, Jason M. Pinger
Neural Circuit Mechanisms Underlying Behavioral Evolution in Drosophila, Laura Fairbanks Seeholzer
Daple Orients and Patterns Sensory Hair Bundles in the Inner Ear, Kimberly Siletti
Chemical Approaches to Dynein Inhibition, Jonathan Baruch Steinman
Netrin Guides Spinal Commissural Axons to the Midline at Long Range Through the Receptors DCC and Neogenin, Sze Sing Shaun Teo
Targeting the CD4 Binding Site of HIV, Lotta von Boehmer
The Role of Neuronal Pentraxin 1 in Promoting Pancreatic Cancer Progression, Yuehyi Gloria Wu
Control of Salmonella Virulence by Microbiota-Derived and Dietary Fatty Acids, Zhenrun J. Zhang
2017
Home Sweet Home: Epigenetic Paths of Stem Cells In and Out of Their Niche, Rene C. Adam
Investigating Differentiation: A Role for Organelle Inheritance in Epidermal Growth, Amma Asare
Light Stimulation of Sensory Hair Cells, Julien Azimzadeh
The Apoptotic and Wallerian Degeneration Pathways Regulate Disease Onset and Progression in the SOD-1G93A Transgenic Mouse Model of ALS, Deanna Belsky
The Physics of Rodent Ultrasonic Vocalizations, Matthew Dornfeld
Apobec1-Mediated RNA Editing in Monocytes Contributes to Genetic Heterogeneity and Modulates Monocyte Activity and Development, Violeta Rayón Estrada
Density-Dependent Foraging in Caenorhabditis Elegans, Joshua Greene
A Neuronal Circuit Architecture for Angular Integration in Drosophila, Jonathan Green
Structural and Functional Studies of Mycobacterial General Transcription Factors RbpA and CarD, Elizabeth Hubin
Light Sheet Microscopy and Image Analysis of Neural Development and Programmed Cell Death in C. Elegans Embryos, Peter Insley
Deconvoluting Cell-Type Specific 3'UTR Isoform Expression in the Adult and Developing Cerebellum, Saša Jereb
Pathways of NHEJ at Dysfunctional Telomeres and Their Resolution, Roos Anna Karssemeijer
Specification of Stem Cells and Niche During Hair Follicle Morphogenesis, Tamara Ouspenskaia
Isopeptide and Ester Bond Ubiquitination Regulate Degradation of the Human Dopamine Receptor 4, Jennifer C. Peeler
Single Molecule Ligand Binding Studies on CCR5 by Fluorescence Cross-Correlation Spectroscopy, Carlos Rico
Compromising the 20S Proteasome Activates a Quality Control Pathway to Mitigate Proteotoxic Stress, Irit Shachrai
IR Laser-Induced Gene Expression for Tracking Development of Single Embryonic Neurons and Glia in C. Elegans, Anupriya Singhal
Lysin Based Antimicrobial Peptides Against Acinetobacter Baumannii, Mya Thandar
Separate Roles of FAN1 and Fanconi Anemia Proteins in DNA Interstrand Crosslink Repair and Human Disease, Supawat Thongthip
A Comparative Study of Sensory Neuron Synaptic Activity and the Role of Presynaptic Diversity, Specificity, and Regulation in Caenorhabitis Elegans, Donovan Ventimiglia
Regulated Recruitment of the Chromosomal Passenger Complex to Chromatin and Microtubules Promotes Accurate Cell Division, Michael Wheelock
High Throughput Detection of Pseudouridine: Caveats, Conundrums, and a Case for Open Science, Maryam Zaringhalam
2016
Escherichia Coli as a New Platform for the Study of Phosphoinositides, Sergio Botero
Studies Towards the Discovery of Novel Natural Products Through Functional Analysis of Environmental DNA-Encoded Type II Polyketide Synthases, Debjani Chakraborty
The Genetics Of Mosquito Heat-Seeking Behavior, Román A. Corfas
Molecular Basis of Mechanosensitivity, Josefina Ines del Marmol
Investigating the Role of Muscleblind-Like 1 in the Suppression of Breast Cancer Progression, Lisa Fish
Nanobody-Based Interactomic Studies of Single Transcripts During mRNA Maturation, Peter C. Fridy
A Census of Human RNA-Binding Proteins, Stefanie Gerstberger
Selection Dynamics in the Germinal Center During Antibody Affinity Maturation, Alexander Gitlin
Characterization of Skin Immune Reactions Induced by the Contact Sensitizer Diphencyprone in Healthy Volunteers and Metastatic Melanoma Patients, Nicholas Gulati
Plasticity of the Nuclear Pore Complex Revealed With Proteomics, Zhanna Hakhverdyan
Dynamics of HIV-1 Infection and Therapy In Vivo, Joshua Abraham Horwitz
Natural Products From Functional Screening of Soil Metagenomic Libraries, Hala Iqbal
CPISPR-CAS: From a Prokaryotic Immune System to a Gene Editing Tool, Wenyan Jiang
Aversive Olfactory Imprinting in Caenorhabditis Elegans, Xin Jin
Regulatory Architecture of Non-Apoptotic Cell Death Program in C. Elegans, Maxime Jeremie Kinet
Extracellular Metabolic Energetics Can Promote Cancer Progression, Jia Min Loo
Qualitative and Quantitative Regulation of the Leptin Gene in vivo, Yi-Hsueh Lu
Paleovirological Analyses of Endogenous Retroviruses and Host Innate Immune Effectors, Daniel Blanco Melo
Tracking the In Vivo Dynamics of Antigenic Variation in the African Trypanosome, Monica R. Mugnier
Genetic Dissection of Neural Circuits Underlying Value Based Decision Making, Hirofumi Nakayama
Characterization of Mechanisms That Mediate Cancer Metastatic Colonization, Alexander Huan Nguyen
Structural and Functional Characterization of SPOA Domains in Salmonella Typhimurium Type III Secretion Systems, Ryan Q. Notti
Regulation of the Anaphase-Promoting Complex Examined at the Single Cell Level, Andrej Ondracka
Retrograde Activation of a Somatic Transcriptional Program Regulates Distal Axon Degeneration, Jason Pitts
Metabolic Regulation of Gene Expression through Differential Histone Acylation: The Regulation and Function of Histone Crotonylation, Benjamin R. Sabari
Protein Regulators of Phosphoinositides as Promoters of Cancer Metastasis, Caitlin Anne Sengelaub
Analysis of Hepatocyte Secretion Pathways: A Case Study on Hepatic Apolipoproteins, Serum Albumin, and Hepatitis C Virus, Constantin N. Takacs
Reconstitution and Mechanistic Studies on the Staphylococcal agr Quorum Sensing Circuit, Boyuan Wang
Chemical Tools for Exploring IFITM3 S-Palmitoylation and Mechanism, Xiaoqiu Yuan
2015
Why Mosquitoes Bite Some People More Than Others: Metabolic Correlates of Human Attraction in AEDES AEGYPTI, Lindsay Lee Bellani
Mechanism of Action of ING4 as a Transcriptional Coactivator of p53, Jabez Bok
Metagenomics-Based Tryptophan Dimer Natural Product Discovery and Development Pipeline, Fang-Yuan Chang
Mechanisms of Olfactory Plasticity in Caenorhabditis Elegans, Christine Cho
Synapse Formation in the Zebrafish Lateral Line, Eliot Dow
Normalization Among Heterogeneous Population Confers Stimulus Discriminability on the Macaque Face Patch Neurons, Akinori F. Ebihara
Effects of Temporal and Spatial Context Within the Macaque Face-Processing System, Clark Andrew Fisher
Therapeutic Uses of Broadly Neutralizing Anti-HIV-1 Antibodies in Humanized Mice, Ariel Halper-Stromberg
Studies on the Maturation of Secreted Quorum Sensing Peptides That Regulates S. Aureus Virulence, Jeffrey Grant Johnson
Investigating Mechanisms of Telomere End-Protection, Shaheen Kabir
The Effect of Chronic Hypertension on Neuropathology in the TGSWDI Mouse Model of Alzheimer's Disease, Anna Kruyer
A Mechanism for Spatial Orientation Based on Sensory Adaptation in Caenorhabditis Elegans, Johannes Larsch
Identification of TMEM2 as a SOX4 Transcriptional Target Involved in Breast Cancer Metastasis, Hyeseung Lee
Hair Bundles of a Jawless Vertebrate Employ Tetrapod-Like Tuned Mechanical Amplification, Katherine J. Leitch
A Genomic Portrait of Hepatitis C Virus and MicroRNA-122, Joseph M. Luna
Functional Dissection of Brainstem Circuitry, Alexander Ryan Nectow
A Reductionist Approach to Modeling Human Corticogenesis, Mohammad Zeeshan Ozair
A Reductionist Approach to Modeling Human Corticogenesis, Mohammad Zeeshan Ozair
Specialized Signals for Spatial Attention in the Ventral and Dorsal Visual Streams, Pablo Polosecki
Characterization of Bacterial Metabolites Involved in Host Pathogen Resistance, Kavita J. Rangan
Molecular Determinants of Tumor Re-Initiation in Breast Cancer, Jason Barzel Ross
Mechanical Control of Sensory Hair-Bundle Function, Joshua D. Salvi
Activity Based Profiling: New Insights into Metabolic Homeostasis, Keith Tan
Xenopus DPPA2 is a Direct Inhibitor of Microtubule Polymerization Required for Nuclear Assembly, John Zhao Xue
Neural Circuit Dependence of Acute and Subacute Nociception in C. Elegans, Yifan Xu
A New Role for Beta-Amyloid in Alzheimer's Disease: Initiation of Thrombotic and Inflammatory Processes Via Coagulation Factor XII and Fibrinogen, Daria Zamolodchikov