Student Theses and Dissertations
The Rockefeller University has awarded over one thousand Ph.D’s since 1959. This collection contains theses beginning with the graduating class of 2006. Earlier theses are added by request or as permission to digitize is received. For more information visit the FAQ page.
2020
Structural and Functional Studies of the Unconventional Proteobacterial Transcription Activator CRL in Complex with the Transcription Machinery, Alexis Jaramillo Cartagena
Cryo-EM Studies of Bacterial RNA Polymerase, James Chen
DDI1/2 and RTF2-Dependent Regulation of RNASE H2 at the Replisome Ensures Genome Stability, Brooke A. Conti
Diverse Kappa Opioid Receptor Agonists: Relationships Between Signaling and Behavior, Amelia Dunn
Monogenic Defects of the Type 1 Interferon Signaling Pathway in Human: Molecular and Clinical Implications, Nicholas Hernandez
Monogenic Defects of the Type I Interferons Signaling Pathway in Humans: Molecular and Clinical Implications, Nicholas Hernandez
Small Molecule Activation of Yap for Inner-Ear Regeneration and Beyond, Nathaniel Kastan
Small-Molecule Activation of YAP for Inner-Ear Regeneration and Beyond, Nathaniel Kastan
Molecular Mechanisms and Antigen Receptor Requirements for Lymphocyte Adaptation to Intestinal Tissues, Mariya B. London
Identification of Previously Unknown Interactions Between G Protein-Coupled Receptors and Receptor Activity-Modifying Proteins, Emily Margaretha Lorenzen
Sympathy for the Microbiota: How Changes in Gut Microbial Composition Influence the Immune System and Basic Physiology by Way of the Sympathetic Nervous System, Paul Andrew Muller
Mechanisms of Evasion: Anti-Tumor Immune Suppression & TRNA-Dependent Growth in Cancer Metastasis, Lisa Brooke Noble
Cas9-Primed Adaptive Immunity During the CRISPR-Cas Response, Philip M. Nussenzweig
A Network Approach to Understanding miRNA Regulation in Adipose Tissue, Sean O’Connor
Germline Genetic Determination of Cancer Outcome, Benjamin N. Ostendorf
Dissection of Neurons and Circuits Involved in Regulating Innate Behaviors, Movement and Higher Cognitive Functions in Mice, Luca Parolari
Analyzing Resistance to Design Chemical Inhibitors of AAA Proteins, Rudolf Pisa
Chemical Biology of Dynein, Cristina C. Santarossa
A Role for Mindbomb 1 in Adenovirus Genome Delivery, Stephanie Sarbanes
Genetic Functional Dissection of the Synaptic Output of a Dual-Function Integrating Neuron, Aylesse Sordillo
Testing the T-loop Model of Telomeric End Protection, Leonid Alexeevich Timashev
CRISPR/CASTE: Functional Genomic Studies of the Major Evolutionary Innovations of Ants, Waring Trible
Identification of Gene Expression Changes in Sleep Mutants Associated With Reduced Longevity in Drosophila, Zikun Wang
Molecular Characterization of Mammalian De Novo DNA Methyltransferase Chromatin Recruitment, Daniel N. Weinberg
Cell Memory and Fate in Human Development, Anna Kresovich Yoney
Representations of Reward and Movement in Drosophila Dopaminergic Neurons, Aryeh Zolin
2019
In Vitro, In Vivo, and In Silico Studies of Reticulospinal Circuits and Generalized Arousal, Adele Bubnys
Sensory Coding and Olfactory Integration in Caenorhabditis Elegans, May Dobosiewicz
On the Interactions of Augmin with Microtubules and the Mechanics of the Cross-Linker PRC1, Alejandro Dottore
Spontaneity and Precision in the Drosophila Central Nervous System, Bennett Ferris
Regulation of Protein Degradation by ADP-Ribosylation, Yetis Gultekin
Dopamine and the Temporal Dependence of Learning and Memory, Annie Handler
Generation of Memory of Infection During the CRISPR-Cas9 Immune Response, Robert Heler
Elucidation of the Functional Architecture of the Early Pre-Ribosomal Processing Machinery in Yeast, Mirjam Hunziker
Substrate Identification of an Oncogenic Kinase: Elucidating the Pathogenesis of a Rare Liver Cancer, Melissa Jarmel
From Face Perception to Individual Recognition: The Missing Link, Sofia Mariana Landi
The Skin Remembers: Epigenetic Memories of Inflammation Past, Samantha B. Larsen
Molecular Mechanisms Underlying Stress-Induced GLIA Remodeling in the Nematode C. Elegans, In Hae Lee
Multimodal Strategies of Host-Seeking Mosquitoes, Molly Zhen Liu
Oxytocin, Dopamine, and the Neuromodulation of Mating Behavior in C. Elegans, Meghan Aileen Lockard
Neural Mechanisms that Control an Innate Foraging Behavior in Caenorhabditis Elegans, Alejandro Lopez-Cruz
The Role and Control of WNT Signalling in an HESC Model of Human Primitive Streak, Iain Martyn
Functional Organization of Molecular Memories in the CRISPR-Cas Immune System, Jon McGinn
Center Manifold Dynamics in Randomly Coupled Oscillators and in Cochlea, Dimitrios Moirogiannis
Distinct Populations of Layer 5B Pyramidal Neurons in the Primary Motor Cortex, Maria V. Moya
Examining Mechanisms Regulating Microtubule Assembly and Function, Melissa Pamula
Molecular Characterization of Novel Mutations in Fanconi Anemia Patients, Kimberly Rickman
The Role of ZMYND8 in Immunoglobulin Class Switch Recombination, Daniel Benjamin Rosen
Non-Coding RNA Features Critical to the Replication of HIV-1, Matthew A. Takata
GPCR Activation of the G Protein-Gated Inward Rectifier Potassium Channel, Kouki Touhara
GPCR Activation of the G Protein-Gated Inward-Rectifier Potassium Channel, Kouki Touhara
Who Said That? Towards a Machine-Prediction-Based Approach to Tursiops Truncatus Whistle Localization and Attribution in a Reverberant Dolphinarium, Sean Fisher Woodward
2018
Cell Cycle Control by Cyclin-CDKS in Chlamydomonas ReinhardtII, Kenneth C. Atkins
Making Ribosomes: Biochemical and Structural Studies of Early Ribosome Biogenesis in Yeast, Malik Chaker-Margot
Single Cell Analysis of the HIV-1 Latent Reservoir, Lillian Brumer Cohn
Dopaminergic Modulation Shapes Sensorimotor Processing in the Drosophila Mushroom Body, Raphael Cohn
Multi-Modal Effects of the Repellent Deet Across Protostomia, Emily Jane Dennis
Biological Consequences of Atypical Phage Conversion in Gram-Positive Pathogens, Douglas R. Deutsch
Characterizing Human Transfer RNAS by Hydro-TRNASEQ and PAR-CLIP, Tasos Gogakos
Investigating Genetic (IN)Compatibility Between Temperate Phages and CRISPR-CAS Systems in Staphylococcus Aureus, Gregory W. Goldberg
Modeling Alzheimer's Disease in Induced Pluripotent Stem Cells, Andrew Gregg
The Characterization of a Novel Complex Implicated in the Initiation of Apoptosis, Thomas Hsiao
Identification and Characterization of Hells-CDCA7, a Nucleosome Remodeling Complex Required for Mitotic Chromosome Structure, Christopher Jenness
A Role for PI31-Mediated Proteasome Regulation in Proteostasis and Neuronal Health, Sandra Jones
Cell Type Specific Roles of Serotonin Receptor 4 in the Hippocampus and Neocortex in Emotion and Cognition, Remzi Karayol
Components Required for the Death and Degradation of the Linker Cell in C. Elegans, Lena Marlise Kutscher
Robustness Enhancement of Sensory Transduction by Hair Bundles, Andrew Robert Milewski
In Search of Generic Properties of Evolved Systems: From Elasticity of Proteins to Structure of Metabolic Networks, Michael Robert Mitchell
A High-Throughput Approach to Uncover Novel Roles of APOBEC2, a Functional Orphan of the AID/APOBEC Family, Linda Molla
Characterization and Reconstitution of S-Palmitoylated IFITM3 Antiviral Activity, Avital Percher
Surface Coat Replacement Dynamics and Antigen Glycosylation in T. Brucei Influence Evasion of the Host Antibody Response, Jason M. Pinger
Neural Circuit Mechanisms Underlying Behavioral Evolution in Drosophila, Laura Fairbanks Seeholzer
Daple Orients and Patterns Sensory Hair Bundles in the Inner Ear, Kimberly Siletti
Chemical Approaches to Dynein Inhibition, Jonathan Baruch Steinman
Netrin Guides Spinal Commissural Axons to the Midline at Long Range Through the Receptors DCC and Neogenin, Sze Sing Shaun Teo
Targeting the CD4 Binding Site of HIV, Lotta von Boehmer
The Role of Neuronal Pentraxin 1 in Promoting Pancreatic Cancer Progression, Yuehyi Gloria Wu
Control of Salmonella Virulence by Microbiota-Derived and Dietary Fatty Acids, Zhenrun J. Zhang
2017
Home Sweet Home: Epigenetic Paths of Stem Cells In and Out of Their Niche, Rene C. Adam
Investigating Differentiation: A Role for Organelle Inheritance in Epidermal Growth, Amma Asare
Light Stimulation of Sensory Hair Cells, Julien Azimzadeh
The Apoptotic and Wallerian Degeneration Pathways Regulate Disease Onset and Progression in the SOD-1G93A Transgenic Mouse Model of ALS, Deanna Belsky
The Physics of Rodent Ultrasonic Vocalizations, Matthew Dornfeld
Apobec1-Mediated RNA Editing in Monocytes Contributes to Genetic Heterogeneity and Modulates Monocyte Activity and Development, Violeta Rayón Estrada
Density-Dependent Foraging in Caenorhabditis Elegans, Joshua Greene
A Neuronal Circuit Architecture for Angular Integration in Drosophila, Jonathan Green
Structural and Functional Studies of Mycobacterial General Transcription Factors RbpA and CarD, Elizabeth Hubin
Light Sheet Microscopy and Image Analysis of Neural Development and Programmed Cell Death in C. Elegans Embryos, Peter Insley
Deconvoluting Cell-Type Specific 3'UTR Isoform Expression in the Adult and Developing Cerebellum, Saša Jereb
Pathways of NHEJ at Dysfunctional Telomeres and Their Resolution, Roos Anna Karssemeijer
Specification of Stem Cells and Niche During Hair Follicle Morphogenesis, Tamara Ouspenskaia
Isopeptide and Ester Bond Ubiquitination Regulate Degradation of the Human Dopamine Receptor 4, Jennifer C. Peeler
Single Molecule Ligand Binding Studies on CCR5 by Fluorescence Cross-Correlation Spectroscopy, Carlos Rico
Compromising the 20S Proteasome Activates a Quality Control Pathway to Mitigate Proteotoxic Stress, Irit Shachrai