Student Theses and Dissertations

 

The Rockefeller University has awarded over one thousand Ph.D’s since 1959. This collection contains theses beginning with the graduating class of 2006. Earlier theses are added by request or as permission to digitize is received. For more information visit the FAQ page.

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2020

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Visualizing Protease Activation, Retrochmp3 Activity, and VPR Recruitment During HIV-1 Assembly, Kate Bredbenner

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Hybridization in Ants, Ian Butler

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Time-Restricted Feeding Extends Longevity in Drosophila Melanogaster, Daniel Cabrera

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Structural and Functional Studies of the Unconventional Proteobacterial Transcription Activator CRL in Complex with the Transcription Machinery, Alexis Jaramillo Cartagena

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Cryo-EM Studies of Bacterial RNA Polymerase, James Chen

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DDI1/2 and RTF2-Dependent Regulation of RNASE H2 at the Replisome Ensures Genome Stability, Brooke A. Conti

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Diverse Kappa Opioid Receptor Agonists: Relationships Between Signaling and Behavior, Amelia Dunn

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Monogenic Defects of the Type 1 Interferon Signaling Pathway in Human: Molecular and Clinical Implications, Nicholas Hernandez

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Monogenic Defects of the Type I Interferons Signaling Pathway in Humans: Molecular and Clinical Implications, Nicholas Hernandez

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Small Molecule Activation of Yap for Inner-Ear Regeneration and Beyond, Nathaniel Kastan

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Small-Molecule Activation of YAP for Inner-Ear Regeneration and Beyond, Nathaniel Kastan

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Molecular Mechanisms and Antigen Receptor Requirements for Lymphocyte Adaptation to Intestinal Tissues, Mariya B. London

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Identification of Previously Unknown Interactions Between G Protein-Coupled Receptors and Receptor Activity-Modifying Proteins, Emily Margaretha Lorenzen

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Sympathy for the Microbiota: How Changes in Gut Microbial Composition Influence the Immune System and Basic Physiology by Way of the Sympathetic Nervous System, Paul Andrew Muller

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Mechanisms of Evasion: Anti-Tumor Immune Suppression & TRNA-Dependent Growth in Cancer Metastasis, Lisa Brooke Noble

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Cas9-Primed Adaptive Immunity During the CRISPR-Cas Response, Philip M. Nussenzweig

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A Network Approach to Understanding miRNA Regulation in Adipose Tissue, Sean O’Connor

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Germline Genetic Determination of Cancer Outcome, Benjamin N. Ostendorf

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Dissection of Neurons and Circuits Involved in Regulating Innate Behaviors, Movement and Higher Cognitive Functions in Mice, Luca Parolari

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Analyzing Resistance to Design Chemical Inhibitors of AAA Proteins, Rudolf Pisa

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Chemical Biology of Dynein, Cristina C. Santarossa

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A Role for Mindbomb 1 in Adenovirus Genome Delivery, Stephanie Sarbanes

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Genetic Functional Dissection of the Synaptic Output of a Dual-Function Integrating Neuron, Aylesse Sordillo

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Testing the T-loop Model of Telomeric End Protection, Leonid Alexeevich Timashev

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CRISPR/CASTE: Functional Genomic Studies of the Major Evolutionary Innovations of Ants, Waring Trible

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Identification of Gene Expression Changes in Sleep Mutants Associated With Reduced Longevity in Drosophila, Zikun Wang

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Molecular Characterization of Mammalian De Novo DNA Methyltransferase Chromatin Recruitment, Daniel N. Weinberg

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Cell Memory and Fate in Human Development, Anna Kresovich Yoney

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Representations of Reward and Movement in Drosophila Dopaminergic Neurons, Aryeh Zolin

2019

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In Vitro, In Vivo, and In Silico Studies of Reticulospinal Circuits and Generalized Arousal, Adele Bubnys

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Chemical Biology, Biochemical and Structural Studies of MDN1, an AAA Protein Required for Ribosome Biogenesis, Zhen Chen

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Sensory Coding and Olfactory Integration in Caenorhabditis Elegans, May Dobosiewicz

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On the Interactions of Augmin with Microtubules and the Mechanics of the Cross-Linker PRC1, Alejandro Dottore

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Spontaneity and Precision in the Drosophila Central Nervous System, Bennett Ferris

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Regulation of Protein Degradation by ADP-Ribosylation, Yetis Gultekin

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Dopamine and the Temporal Dependence of Learning and Memory, Annie Handler

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Generation of Memory of Infection During the CRISPR-Cas9 Immune Response, Robert Heler

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A Stress-Induced TRNA Depletion Response Mediates Codon-Based Translational Repression and Growth Suppression, Doowon Huh

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Elucidation of the Functional Architecture of the Early Pre-Ribosomal Processing Machinery in Yeast, Mirjam Hunziker

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Substrate Identification of an Oncogenic Kinase: Elucidating the Pathogenesis of a Rare Liver Cancer, Melissa Jarmel

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Modeling Alzheimer's Disease Using CRISPR/CAS9 Gene Editing and Induced Pluripotent Stem Cells Reveals Conserved Cellular Mechanisms, Dylan Kwart

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From Face Perception to Individual Recognition: The Missing Link, Sofia Mariana Landi

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The Skin Remembers: Epigenetic Memories of Inflammation Past, Samantha B. Larsen

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Molecular Mechanisms Underlying Stress-Induced GLIA Remodeling in the Nematode C. Elegans, In Hae Lee

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Multimodal Strategies of Host-Seeking Mosquitoes, Molly Zhen Liu

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Oxytocin, Dopamine, and the Neuromodulation of Mating Behavior in C. Elegans, Meghan Aileen Lockard

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Neural Mechanisms that Control an Innate Foraging Behavior in Caenorhabditis Elegans, Alejandro Lopez-Cruz

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The Role and Control of WNT Signalling in an HESC Model of Human Primitive Streak, Iain Martyn

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Functional Organization of Molecular Memories in the CRISPR-Cas Immune System, Jon McGinn

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Center Manifold Dynamics in Randomly Coupled Oscillators and in Cochlea, Dimitrios Moirogiannis

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Distinct Populations of Layer 5B Pyramidal Neurons in the Primary Motor Cortex, Maria V. Moya

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Examining Mechanisms Regulating Microtubule Assembly and Function, Melissa Pamula

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Conformational Dynamics of the Nuclear Pore Complex Studied With Coarse-Grained Modelling and Polarized Light Microscopy, Joan Pulupa

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Molecular Characterization of Novel Mutations in Fanconi Anemia Patients, Kimberly Rickman

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The Role of ZMYND8 in Immunoglobulin Class Switch Recombination, Daniel Benjamin Rosen

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Non-Coding RNA Features Critical to the Replication of HIV-1, Matthew A. Takata

GPCR Activation of the G Protein-Gated Inward Rectifier Potassium Channel, Kouki Touhara

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GPCR Activation of the G Protein-Gated Inward-Rectifier Potassium Channel, Kouki Touhara

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Who Said That? Towards a Machine-Prediction-Based Approach to Tursiops Truncatus Whistle Localization and Attribution in a Reverberant Dolphinarium, Sean Fisher Woodward

2018

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Cell Cycle Control by Cyclin-CDKS in Chlamydomonas ReinhardtII, Kenneth C. Atkins

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Making Ribosomes: Biochemical and Structural Studies of Early Ribosome Biogenesis in Yeast, Malik Chaker-Margot

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Single Cell Analysis of the HIV-1 Latent Reservoir, Lillian Brumer Cohn

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Dopaminergic Modulation Shapes Sensorimotor Processing in the Drosophila Mushroom Body, Raphael Cohn

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Multi-Modal Effects of the Repellent Deet Across Protostomia, Emily Jane Dennis

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Biological Consequences of Atypical Phage Conversion in Gram-Positive Pathogens, Douglas R. Deutsch

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Characterizing Human Transfer RNAS by Hydro-TRNASEQ and PAR-CLIP, Tasos Gogakos

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Investigating Genetic (IN)Compatibility Between Temperate Phages and CRISPR-CAS Systems in Staphylococcus Aureus, Gregory W. Goldberg

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Modeling Alzheimer's Disease in Induced Pluripotent Stem Cells, Andrew Gregg

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The Characterization of a Novel Complex Implicated in the Initiation of Apoptosis, Thomas Hsiao

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Identification and Characterization of Hells-CDCA7, a Nucleosome Remodeling Complex Required for Mitotic Chromosome Structure, Christopher Jenness

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A Role for PI31-Mediated Proteasome Regulation in Proteostasis and Neuronal Health, Sandra Jones

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Cell Type Specific Roles of Serotonin Receptor 4 in the Hippocampus and Neocortex in Emotion and Cognition, Remzi Karayol

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Components Required for the Death and Degradation of the Linker Cell in C. Elegans, Lena Marlise Kutscher

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Robustness Enhancement of Sensory Transduction by Hair Bundles, Andrew Robert Milewski

In Search of Generic Properties of Evolved Systems: From Elasticity of Proteins to Structure of Metabolic Networks, Michael Robert Mitchell

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A High-Throughput Approach to Uncover Novel Roles of APOBEC2, a Functional Orphan of the AID/APOBEC Family, Linda Molla

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Characterization and Reconstitution of S-Palmitoylated IFITM3 Antiviral Activity, Avital Percher

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Surface Coat Replacement Dynamics and Antigen Glycosylation in T. Brucei Influence Evasion of the Host Antibody Response, Jason M. Pinger

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Neural Circuit Mechanisms Underlying Behavioral Evolution in Drosophila, Laura Fairbanks Seeholzer

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Daple Orients and Patterns Sensory Hair Bundles in the Inner Ear, Kimberly Siletti

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Chemical Approaches to Dynein Inhibition, Jonathan Baruch Steinman

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Netrin Guides Spinal Commissural Axons to the Midline at Long Range Through the Receptors DCC and Neogenin, Sze Sing Shaun Teo

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Targeting the CD4 Binding Site of HIV, Lotta von Boehmer

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IGDB-2, an IG/FNIII Protein, Binds the ION Channel LGC-34 and Controls Sensory Compartment Morphogenesis in C. Elegans, Wendy Wang

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The Role of Neuronal Pentraxin 1 in Promoting Pancreatic Cancer Progression, Yuehyi Gloria Wu

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Control of Salmonella Virulence by Microbiota-Derived and Dietary Fatty Acids, Zhenrun J. Zhang

2017

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Home Sweet Home: Epigenetic Paths of Stem Cells In and Out of Their Niche, Rene C. Adam

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Investigating Differentiation: A Role for Organelle Inheritance in Epidermal Growth, Amma Asare

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Light Stimulation of Sensory Hair Cells, Julien Azimzadeh

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The Apoptotic and Wallerian Degeneration Pathways Regulate Disease Onset and Progression in the SOD-1G93A Transgenic Mouse Model of ALS, Deanna Belsky

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The Physics of Rodent Ultrasonic Vocalizations, Matthew Dornfeld

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Apobec1-Mediated RNA Editing in Monocytes Contributes to Genetic Heterogeneity and Modulates Monocyte Activity and Development, Violeta Rayón Estrada

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Density-Dependent Foraging in Caenorhabditis Elegans, Joshua Greene

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A Neuronal Circuit Architecture for Angular Integration in Drosophila, Jonathan Green

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Structural and Functional Studies of Mycobacterial General Transcription Factors RbpA and CarD, Elizabeth Hubin

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Light Sheet Microscopy and Image Analysis of Neural Development and Programmed Cell Death in C. Elegans Embryos, Peter Insley

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Deconvoluting Cell-Type Specific 3'UTR Isoform Expression in the Adult and Developing Cerebellum, Saša Jereb

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Pathways of NHEJ at Dysfunctional Telomeres and Their Resolution, Roos Anna Karssemeijer

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Transcriptional Governance of Hair Follicle Stem Cell Quiescence and Niche Maintenance in Long-Term Tissue Regeneration, Kenneth Lay

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Specification of Stem Cells and Niche During Hair Follicle Morphogenesis, Tamara Ouspenskaia