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McLean, F. Bone
The Rockefeller University
Franklin C. McLean, Marshall R. Urist. Bone; fundamentals of the physiology of skeletal tissue
The third edition of this very interesting work contains all that is new about the physiology of bone. It also contains material concerning the hinterland between physiology and pathology of the substance we call “bone”.
The author’s scope is an extensive one and includes various aspects of morphology, experimental embryology, phylogeny, histochemistry, enzyme chemistry, crystallography, endocrinology, electron microscopy, autoradiography, and neuroradiology. There is a comprehensive and extensive bibliography as well as a very complete index. This monograph will take its place all over the world as the reference volume on the physiology of skeletal tissue. -- British Journal of Surgery
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Michaelis, L. Die bindungsgesetze von Toxin und Antitoxin
The Rockefeller University
Leonor Michaelis. Die bindungsgesetze von Toxin und Antitoxin
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Michaelis, L. Hydrogen ion concentration
The Rockefeller University
Leonor Michaelis. Hydrogen ion concentration, its significance in the biological sciences and methods for its determinations
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Michaelis, L. Oxidation-reduction potentials
The Rockefeller University
Leonor Michaelis, Louis B. Flexner. Oxidation-reduction potentials
Series: Monographs on experimental biology
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Miller. G. Language and communication
The Rockefeller University
George A. Miller. Language and communication
Series: McGraw-Hill publications in psychology
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Miller, G. Mathematics and psychology
The Rockefeller University
George A. Miller. Mathematics and psychology
Series: Perspectives in psychology
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Miller, G. Spontaneous apprentices
The Rockefeller University
George A. Miller. Spontaneous apprentices: children and language
Series: Tree of life
As a unifying metaphor, Spontaneous apprentices takes its title from experiments Dr. Miller describes throughout the volume in regard to the acquisition of language by children. This process, it becomes clear, flows from a freely entered upon an apprenticeship in which children learn much more than adults could consciously teach them. So likewise, science must become openly receptive – even childlike – toward nature and recognize the importance of the ostensibly “insignificant”. The real course of knowledge is not a succession of revolutions bur hard work carried on with normal human passions and confusions intended to reduce the number of alternative views of the universe a rational person might subscribe to.
At once an autobiography of “research in progress” and a philosophical statement, Spontaneous apprentices reveals insights in understanding which science and society will need for decades to come.
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Miller, G. The psychology of communication
The Rockefeller University
George A. Miller. The psychology of communication; seven essays
The seven essays in this book range from cybernetics and automation to psycholinguistics, but underneath there is a persistent concern with common subject: man as an information-processing and information-gathering system.
“Most of these essays deal explicitly with psychological aspects of communication. Some reflect a communicative concern less directly. Memory, for example, is a communication from the past to the future, and the channel it travels from source to destination is often the human nervous system; the problem is to encode the message in such a way as to resist the ubiquitous noise that this channel introduces…And the concern with computers – a computer is simply the most general possible case of an information-processing system, one that can transform the information in any describable manner before passing in on.” – From the author's Preface
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Müller, M./editor. Biochemistry and molecular biology of parasites
The Rockefeller University
J. Joseph Marr, Miklós Müller/editors. Biochemistry and molecular biology of parasites
The study of parasitic organisms at the molecular level has yielded fascinating new insights of great medical, social, and economical importance, and has pointed the way for the treatment and prevention of the diseases they cause. Biochemistry and Molecular Biology of Parasites presents an up-to-date account of this modern scientific discipline in a manner that allows and encourages the reader to place the biochemistry and molecular biology of these organisms in their biological context. The chapters are cross-referenced and grouped in an arrangement that provides a fully integrated whole and permits the reader to create a composite of the biochemical function of these organisms. The individual chapter includes those devoted to metabolism, in both aerobic and anaerobic protozoa; antioxidant mechanisms; parasite surfaces; organelles; invasion mechanisms; and chemotherapy. The helminths are discussed not only from the point of view of their cellular biochemistry and metabolism, but also with respect to both their integrated functions such as neurochemistry, structure, and functions of surfaces and reproduction. Written by expert investigators, this book will be of interest to all experienced researchers, graduate students, and to the newcomer eager to become familiar with the biochemistry and molecular biology of parasites.---Google Books review
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Müller, M./editor. Origin of mitochondria and hydrogenosomes
The Rockefeller University
William F. Martin, Miklós Müller/editors. Origin of mitochondria and hydrogenosomes
The evolutionary origins of hydrogenosomes have been the subject of considerable debate. From early days it was apparent that hydrogenosomes had evolved on multiple occasions in different eukaryotes, but from which progenitor organelle or endosymbiont was unresolved. Work from many different laboratories has contributed towards formulating the current hypothesis that hydrogenosomes and mitosomes, their even more reduced cousins, and share common ancestry with mitochondria. Their shared similarities, for example, their common mechanisms of protein import and their double membrane, can be explained by common ancestry, and their differences by descent with modification under contrasting lifestyles. The hypothesis that mitochondria, mitosomes, and hydrogenosomes are homologous, predicts that, as the organelles are studied more deeply, additional shared features will be revealed.
However, it is already apparent from the contributions to this volume, that identifying the genetic contribution to eukaryotes of the mitochondrial endosymbiosis, and revealing the functions of its descendent organelles, are key to understanding eukaryotic biology and evolution.
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Murphy, J. The lymphocyte in resistance
The Rockefeller University
James B. Murphy. The lymphocyte in resistance to tissue grafting, malignant disease, and tuberculous infection: an experimental study
Series: Monographs of the Rockefeller Institute for Medical Research; no. 21
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Nurse, P. The great ideas of biology
The Rockefeller University
Paul Nurse. The great ideas of biology: the Romanes lecture for 2003 delivered before the University of Oxford on 30 October 2003
Paul Nurse focuses on four discoveries in The Great Ideas of Biology: the cell, the gene, evolution by natural selection, and life as chemistry. The development of good microscopes made the discovery of the cell possible, although it was not until the later nineteenth century that it was accepted that all living organisms, regardless of their complexity, emerged from a single cell. The discovery of the gene followed the idea that all living organisms have the ability to reproduce and generate offspring that resemble their parents. Gregor Mendel's crosses with plants and analyses of the outcomes in the 1860s led him to become the father of genetics, and in the mid-twentieth century, DNA was shown to be the genetic material. Natural selection, the idea of the survival of the fittest, is one of the best-known ideas of biology, proposed by Charles Darwin in 1859. The idea that many of life's activities can be understood in terms of chemistry had its origins in studies of fermentation, and biochemistry was born when it was shown that an enzyme from yeast cells, i.e. a living organism, was responsible for the chemical reactions that turned grape juice into alcohol. At that point, it was postulated that cells should be understood as a chemical machine. Paul Nurse concludes that the current challenge for biologists is to focus on a biological organization which works on a range of levels, from cells through to organisms and ecosystems. --Google Books review
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Opie, E. Disease of the pancreas
The Rockefeller University
Eugene L. Opie. Disease of the pancreas, its cause and nature
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Osterhout, W. J. V. Some fundamental problems of cellular physiology
The Rockefeller University
W. J. V. Osterhout. Some fundamental problems of cellular physiology
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Osterhout, W. J. V. The nature of life
The Rockefeller University
W. J. V. Osterhout. The nature of life
Series: Colver lectures; 1922
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Ott, J. Analysis of human genetic linkage
The Rockefeller University
Jurg Ott. Analysis of human genetic linkage
The first and still the only book of its kind, this volume offers a concise introduction to human genetic linkage analysis and gene mapping. Jurg Ott provides mathematical and statistical foundations of linkage analysis for researchers and practitioners, as well as practical comments on available computer programs and websites. Each chapter ends with a set of problems, whose solutions are found at the end of the book.
New to this edition is a chapter on complex traits, such as diabetes, some cancers, and psychiatric conditions. Also new is an overview of nonparametric approaches to linkage and association analysis. A chapter on two-locus inheritance introduces the reader to many of the intricate aspects of complex traits. Although the book's primary audience is in the field of genetics, physicians, and others without sophisticated training in genetics can understand and apply the principles and techniques discussed. (John Hopkins University Press)
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Ott, J. Handbook of human genetic linkage
The Rockefeller University
Joseph Douglas Terwilliger, Jurg Ott. Handbook of human genetic linkage Two-point linkage analysis -- File system used by LINKAGE -- Running the LINKAGE programs MLINK and ILINK -- Setting up a linkage analysis using LCP -- Elementary usage of the affection status locus type -- Sex-linked recessive diseases -- Loops -- Locus types I: allele numbers and binary factors -- Advanced applications of affection status I: incomplete penetrance revisited -- Advanced applications of the affection status locus type II -- LIPED program -- Multipoint linkage analysis with the LINKAGE package -- Gene mapping in CEPH families -- Locus-ordering problem: CILINK -- CMAP and adding a new locus -- Mapping a disease locus against a fixed map of markers -- Exclusion mapping -- Sex difference in recombination rates: multipoint case -- Introduction to interference -- Advanced topics in linkage analysis -- Mutation rates and the LINKAGE programs -- Gene frequencies and LINKAGE -- Linkage disequilibrium between alleles at marker loci -- Linkage disequilibrium and disease loci -- Parametric analysis of complex diseases. (cont) Nonparametric methods of linkage analysis -- Genetic heterogeneity -- Computer simulation methods -- Linkage utility programs -- Practical considerations -- List of programs, and where to obtain them.
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Pais, A. A tale of two continents : a physicist's life in a turbulent world
The Rockefeller University
Abraham Pais. A tale of two continents: a physicist's life in a turbulent world
In A Tale of Two Continents physicist, Abraham Pais writes of his life in war (hiding from the Gestapo for five years) and peace (learning to call the Dodgers "Bums"). David Gross of the Institute of Theoretical Physics says, "The book teems with anecdotes and stories of the great men and women he encountered, wonderful stories that often capture the personalities of these historical figures in a single paragraph. For the scores of thumbnail portraits alone, the book is worth the price." Pais interleaves his more personal recollections with the story of post-war particle physics, providing the most accessible history of the field yet written.
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Pais, A. Einstein lived here
The Rockefeller University
Abraham Pais. Einstein lived here
This volume is a complement to Pais’s biographical study of Einstein the scientist. Two of the eleven essays are taken from that earlier book. Seven of the remaining are relatively short and may be of marginal interest to most readers. The first and last essays, however, are both more substantive and significant.
Pais opens the volume with a sympathetic, but frank, discussion of Einstein as husband and father. Written in response to recently acquired knowledge that Einstein had an illegitimate daughter, whose fate is unknown, and recent claims regarding the role of Einstein’s first wife in the development of relativity theory, Pais’s account provides an accurate summary of current knowledge for the non-specialist. The picture he draws is of a man too involved in science to work very hard on human relationships. He also successfully deflates the claim that Einstein’s first wife was a collaborator in the theory of relativity.
More than half the book is taken up by the ultimate essay, which discusses the relation of Einstein with the press, starting with a 1902 newspaper advertisement by Einstein and ending with reminiscences published on the occasion of the centennial of Einstein’s birth. Taking a generally chronological approach, Pais combines quotations from and paraphrases of press accounts of Einstein with reports of Einstein’s speeches, letters to the editor, and other Einstein contributions to the press. Although short on analysis, Pais’s essay, with more than four hundred citations, demonstrates the fascination the press (and Pais limited himself to only English-, French-, and German-language publications) had for Einstein. There is also considerable evidence that Einstein was able to widely disseminate his views on non-scientific issues through the mass media. In a word, Einstein was a celebrity.
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Pais, A. Inward bound : of matter and forces in the physical world
The Rockefeller University
Abrahan Pais. Inward bound: of matter and forces in the physical world
In his groundbreaking book, Pais chronicles the history of the physics of matter and physical forces since the discovery of x-rays. He relates not only what has happened over the last one-hundred years, but also why it happened the way it did, the experiences of the scientists involved, and how a series of seemingly bizarre or unrelated occurrences has emerged as a logical sequence of discoveries and events. Personally involved in many of the developments described, Pais provides unique insights into the world of big and small physics, revealing how the smallest distances explored between 1895 and 1983 have shrunk a hundred million-fold. Along with this "road inward," scientists have made advances that later generations will rank among the principal monuments of the twentieth century. This magisterial survey explores the discoveries made on the constituents of matter, the laws that govern them, and the forces that act on them. Demonstrating the sometimes rocky road to new insights, Pais reveals that these have been times of progress and stagnation, of order and chaos, of clarity and confusion, of belief and incredulity, of the conventional and the bizarre, as well as of revolutionaries and conservatives, of science by individuals and by consortia, of little gadgets and big machines, and of modest funds and big money.
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Pais, A. Niels Bohr's times: in physics, philosophy, and polity
The Rockefeller University
Abraham Pais. Niels Bohr's times: in physics, philosophy, and polity
The life of Niels Bohr spanned times of revolutionary change in science itself as well as its impact on society. Along with Albert Einstein, Bohr can be considered to be this century's major driving force behind the new philosophical and mathematical descriptions of the structure of the atom and the nucleus. Abraham Pais, the acclaimed biographer of Albert Einstein, here traces Bohr's progress from his well-to-do origins in late nineteenth-century Denmark to his position at center stage in the world political scene, particularly during the Second World War and the development of atomic weapons. Pais' description moves through the science as it was before Bohr, as it became because of Bohr, and thence to Bohr's scientific and philosophical legacy. That legacy is contained both in theory as it is now universally enshrined, as well as in its practice in such great Danish institutions as Riso. But more than that, Pais captures the essence of Bohr, the intensely private family figure who, despite appalling personal tragedy, became one of the most loved cultural figures of recent times.
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Pais, A. 'Subtle is the Lord - ': the science and the life of Albert Einstein
The Rockefeller University
Abraham Pais. 'Subtle is the Lord -': the science and the life of Albert Einstein
Subtle is the Lord is widely recognized as the definitive scientific biography of Albert Einstein. The late Abraham Pais was a distinguished physicist turned historian who knew Einstein both professionally and personally in the last years of his life. His biography combines a profound understanding of Einstein's work with personal recollections from their years of acquaintance, illuminating the man through the development of his scientific thought.
Pais examines the formulation of Einstein's theories of relativity, his work on Brownian motion, and his response to quantum theory with authority and precision. The profound transformation Einstein's ideas effected on the physics of the turn of the century is here laid out for the serious reader. Pais also fills many gaps in what we know of Einstein's life - his interest in philosophy, his concern with Jewish destiny, and his opinions of great figures from Newton to Freud. This remarkable volume, written by a physicist who mingled in Einstein's scientific circle, forms a timeless and classic biography of the towering figure of twentieth-century science.
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Pais, A. The genius of science : a portrait gallery
The Rockefeller University
Abraham Pais. The genius of science: a portrait gallery
The late Abraham Pais' last book is a collection of nineteen biographical essays on famous twentieth-century physicists, including luminaries like Einstein, Bohr, Pauli, and Dirac. Their common denominator is that Pais knew them all personally, some very well, such as Res Jost, whom he calls `the best friend I ever had', some less so. Although Pais gives ample attention to the scientific achievements of his subjects, it is through his discussion of their lives and personalities that he brings them to life - as he explicitly intended to do. It is always a joy to read Pais' prose, especially in cases such as Jost or George Uhlenbeck, where his deep affection comes to the foreground. In his foreword, Pais draws the reader's attention with some emphasis to the article on Einstein, written for a Danish encyclopedia, in which he had to summarize his extensive historical work on Einstein into a 2000-word essence.
Throughout the volume, Pais illuminates the personalities and achievements of these stellar scientists. The result is virtually a who's who of 20th-century physics--a superb collection of portraits that sheds light on the physicists, their work, and their lasting influence on science.
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Pfaff, D. Central neural states relating sex and pain
The Rockefeller University
Richard J. Bodnar, Kathryn Commons, Donald W. Pfaff. Central neural states relating sex and pain
Hormones strongly influence and even "drive" certain primitive behaviors. In Central Neural States Relating Sex and Pain, Richard J. Bodnar, Kathryn Commons, and Donald W. Pfaff examine hormonal, neural, and genetic mechanisms of reproductive, pain-sensing, and pain-inhibitory systems. The authors show that there are remarkable neuroanatomical, biochemical, and functional overlaps among these systems. They consider sensory inputs triggering both classes of behaviors and focus on the role of sex hormones in modulating both forms of behavior. Sex hormones acting in different regions of the brain not only energize reproductive behaviors but also modulate opioid-dependent pain-inhibitory pathways. The authors also summarize some intriguing gender differences in hormone actions and responsivity to pain.
The clinical implications of this field of research are numerous. Central Neural States Relating Sex and Pain will appeal to anyone interested in new ways of looking at behavioral dispositions as they are influenced by specific genetic, neural, and hormonal states.
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