Ott, J. Handbook of human genetic linkage

Title

Ott, J. Handbook of human genetic linkage

Files

Description

Joseph Douglas Terwilliger, Jurg Ott. Handbook of human genetic linkage Two-point linkage analysis -- File system used by LINKAGE -- Running the LINKAGE programs MLINK and ILINK -- Setting up a linkage analysis using LCP -- Elementary usage of the affection status locus type -- Sex-linked recessive diseases -- Loops -- Locus types I: allele numbers and binary factors -- Advanced applications of affection status I: incomplete penetrance revisited -- Advanced applications of the affection status locus type II -- LIPED program -- Multipoint linkage analysis with the LINKAGE package -- Gene mapping in CEPH families -- Locus-ordering problem: CILINK -- CMAP and adding a new locus -- Mapping a disease locus against a fixed map of markers -- Exclusion mapping -- Sex difference in recombination rates: multipoint case -- Introduction to interference -- Advanced topics in linkage analysis -- Mutation rates and the LINKAGE programs -- Gene frequencies and LINKAGE -- Linkage disequilibrium between alleles at marker loci -- Linkage disequilibrium and disease loci -- Parametric analysis of complex diseases. (cont) Nonparametric methods of linkage analysis -- Genetic heterogeneity -- Computer simulation methods -- Linkage utility programs -- Practical considerations -- List of programs, and where to obtain them.

ISBN

0801848032

Publication Date

1994

Publisher

Johns Hopkins University Press

City

Baltimore

Keywords

human genetics, genetic linkage, data processing

Comments

The Rockefeller University Library 3rd Floor Special Collections QH 445.2 T333 1994

The Rockefeller University Library President's Office OFFICE OF THE PRESIDENT

Ott, J. Handbook of human genetic linkage

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