Submissions from 2016
Dendritic cells induce a subpopulation of IL-12Rβ2-expressing treg that specifically consumes IL-12 to control Th1 responses, Uri Sela, Chaegyu Park, and Andrew Park
Submissions from 2015
ESAT-6 targeting to DEC205+ antigen presenting cells induces specific-T cell responses against ESAT-6 and reduces pulmonary infection with virulent Mycobacterium tuberculosis, Aarón Silva-Sánchez, Selene Meza-Pérez, and Adriana Flores-Langarica
Submissions from 2014
Classical Flt3L-dependent dendritic cells control immunity to protein vaccine, Niroshana Anandasabapathy, Rachel E. Feder, and Shamim A. Mollah
Corrigendum to Murine Langerin+ dermal dendritic cells prime CD8+ T cells while Langerhans ells induce cross-tolerance, Vincent Flacher, Christoph H. Trip, and David G. Mairhofer
Erratum: Flt3L dependence helps define an uncharacterized subset of murine cutaneous dendritic cells, Shamim A. Mollah, Joseph S. Dobrin, and Rachel E. Feder
Flt3L dependence helps define an uncharacterized subset of murine cutaneous dendritic cells, Shamim A. Mollah, Joseph S. Dobrin, and Rachel E. Feder
Direct Type I IFN but Not MDA5/TLR3 Activation of Dendritic Cells Is Required for Maturation and Metabolic Shift to Glycolysis after Poly IC Stimulation, Austin Pantel, Angela Teixeira, and Elias K. Haddad
Submissions from 2013
Specialized role of migratory dendritic cells in peripheral tolerance induction, Juliana Idoyaga, Christopher Fiorese, and Lori Zbytnik
Targeting Leishmania major Antigens to Dendritic Cells In Vivo Induces Protective Immunity, Ines Matos, Olga Mizenina, Ashira Lubkin, Ralph M. Steinman, and Juliana Idoyaga
Lung dendritic cells induce migration of protective T cells to the gastrointestinal tract, Darren Ruane, Lucas Brane, and Bernardo S. Reis
Submissions from 2012
Dll4-Notch signaling in Flt3-independent dendritic cell development and autoimmunity in mice, Fabienne Billiard, Camille Lobry, and Guillaume Darrasse-Jèze
Strategy for identifying dendritic cell-processed CD4+ T cell epitopes from the HIV Gag p24 protein, Leonia Bozzacco, Haiqiang Yu, and Jörn Dengjel
Treml4, an Ig superfamily member, mediates presentation of several antigens to T cells in vivo, including protective immunity to HER2 protein, Hiroaki Hemmi, Neeha Zaidi, and Bei Wang
Decisions about dendritic cells: Past, present, and future, Ralph M. Steinman
Targeting of the non-mutated tumor antigen HER2/neu to mature dendritic cells induces an integrated immune response that protects against breast cancer in mice, Bei Wang, Neeha Zaidi, and Lishen He
Submissions from 2011
Flt3L controls the development of radiosensitive dendritic cells in the meninges and choroid plexus of the steady-state mouse brain, Niroshana Anandasabapathy, Gabriel D. Victora, and Matthew M. Meredith
Synthetic double-stranded RNA induces innate immune responses similar to a live viral vaccine in humans, Marina Caskey, François Lefebvre, and Ali Filali-Mouhim
Flt3 signaling-dependent dendritic cells protect against atherosclerosis, Jae-hoon Choi, Cheolho Cheong, and Guillaume Darrasse-Jèze
Immunization with HIV Gag targeted to dendritic cells followed by recombinant New York vaccinia virus induces robust T-cell immunity in nonhuman primates, Barbara J. Flynn, Kathrin Kastenmüller, and Ulrike Wille-Reece
SnapShot: Dendritic cells, Juliana Idoyaga and Ralph M. Steinman
Newcastle disease virus expressing a dendritic cell-targeted HIV Gag protein induces a potent Gag-specific immune response in mice, Jad Mammary, Frida Array, and Qinshan Gao
Dendritic cells induce antigen-specific regulatory T cells that prevent graft versus host disease and persist in mice, Uri Sela, Peter Olds, and Andrew Park
Submissions from 2010
Microbial stimulation fully differentiates monocytes to DC-SIGN/CD209 + dendritic cells for immune T cell areas, Cheolho Cheong, Ines Matos, and Jae-hoon Choi
Epidermal langerhans cells rapidly capture and present antigens from C-type lectin-targeting antibodies deposited in the dermis, Vincent Flacher, Christoph H. Trip, and Patrizia Stoitzner
Dendritic cell targeted HIV gag protein vaccine provides help to a DNA vaccine including mobilization of protective CD8+ T cells, Godwin W. Nchinda, David Amadu, and Christine Trumpfheller
Submissions from 2009
Identification of antigen-presenting dendritic cells in mouse aorta and cardiac valves, Jae-hoon Choi, Yoonkyung Do, and Cheolho Cheong
A new triggering receptor expressed on myeloid cells (Trem) family member, Trem-like 4, binds to dead cells and is a DNAX activation protein 12-linked marker for subsets of mouse macrophages and dendritic cells, Hiroaki Hemmi, Juliana Idoyaga, and Koji Suda
Antibody to Langerin/CD207 localizes large numbers of CD8α + dendritic cells to the marginal zone of mouse spleen, Juliana Idoyaga, Nao Suda, and Koji Suda
Dendritic cells require a systemic type I interferon response to mature and induce CD4+ Th1 immunity with poly IC as adjuvant, Maria` P. Longhi, Christine Trumpfheller, and Juliana Idoyaga
Synthetic double-stranded RNAs are adjuvants for the induction of t helper 1 and humoral immune responses to human papillomavirus in rhesus macaques, Christiane P. Stahl-Hennig, Martin Eisenblätter, and Edith Yasny
Submissions from 2008
Cutting edge: Langerin/CD207 receptor on dendritic cells mediates efficient antigen presentation on MHC I and II products in vivo, Juliana Idoyaga, Cheolho Cheong, and Koji Suda
An IFN-γ-IL-18 signaling loop accelerates memory CD8+ T cell proliferation, Yochiko Iwai, Hiroaki Hemmi, and Olga Mizenina
Selective delivery of β cell antigen to dendritic cells in vivo leads to deletion and tolerance of autoreactive CD8+ T cells in NOD mice, Arunika Mukhopadhaya, Tadashi Hanafusa, and Irene Jarchum
The efficacy of DNA vaccination is enhanced in mice by targeting the encoded protein to dendritic cells, Godwin W. Nchinda, Janelle Kuroiwa, and Margarita Oks
Dendritic Cells In Vivo: A Key Target for a New Vaccine Science, Ralph M. Steinman
The microbial mimic poly IC induces durable and protective CD4+ T cell immunity together with a dendritic cell targeted vaccine, Christine Trumpfheller, Marina Caskey, and Godwin W. Nchinda
CD80+CD205+ splenic dendritic cells are specialized to induce Foxp3+ regulatory T cells, Sayuri Yamazaki, Diana Dudziak, and Gordon Heidkamp
Submissions from 2007
DEC-205 receptor on dendritic cells mediates presentation of HIV gag protein to CD8+ T cells in a spectrum of human MHC I haplotypes, Leonia Bozzacco, Christine Trumpfheller, and Frederick P. Siegal
Erratum: Sustained expansion of NKT cells and antigen-specific T cells after injection of α-galactosyl-ceramide loaded mature dendritic cells in cancer patients, David H. Chang, Keren Osman, and John E. Connolly
Correction, Madhav V. Dhodapkar, Devi K. Banerjee, and John E. Connolly
Erratum: Selective blockade of the inhibitory Fcγ receptor (FcγRIIB) in human dendritic cells and monocytes induces a type I interferon response program, Madhav V. Dhodapkar, Devi K. Banerjee, and John E. Connolly
Selective blockade of the inhibitory Fcγ receptor (FcγRIIB) in human dendritic cells and monocytes induces a type I interferon response program, Madhav V. Dhodapkar, Devi K. Banerjee, and John E. Connolly
Dendritic cells with TGF-β1 differentiate naïve CD4 +CD25- T cells into islet-protective Foxp3+ regulatory T cells, Xunrong Luo, Kristin V. Tarbell, and Hua Yang
Cross-presentation of glycolipid from tumor cells loaded with α-galactosylceramide leads to potent and long-lived T cell-mediated immunity via dendritic cells, Kanako Shimizu, Yuri Kurosawa, and Masaru Taniguchi
A subset of dendritic cells induces CD4+ T cells to produce IFN-γ by an IL-12-independent but CD70-dependent mechanism in vivo, Helena Soares, Haena Waechter, and Nicolas Glaichenhaus
Atraumatic oral spray immunization with replication-deficient viral vector vaccines, Christiane P. Stahl-Hennig, Seraphin Kuate, and Monika Franz
Dendritic cell-expanded, islet-specific CD4+ CD25+ CD62L+ regulatory T cells restore normoglycemia in diabetic NOD mice, Kristin V. Tarbell, Lucine Petit Francis, and Xiaopan Zuo
Normal human dermis contains distinct populations of CD11c +BDCA-1+ dendritic cells and CD163+FXIIIA + macrophages, Lisa C. Zaba, Judilyn Fuentes-Duculan, and Ralph M. Steinman
Submissions from 2006
Antigen targeting to dendritic cells elicits long-lived T cell help for antibody responses, Silvia B. Boscardin, Julius C.R. Hafalla, and Revati F. Masilamani
Dendritic cell targeting of survivin protein in a xenogeneic form elicits strong CD4+ T cell immunity to mouse survivin, Anna Charalambous, Margarita Oks, and Godwin W. Nchinda
Glycolipid α-C-galactosylceramide is a distinct inducer of dendritic cell function during innate and adaptive immune responses of mice, Shinichiro Fujii, Kanako Shimizu, and Hiroaki Hemmi
HIV-1 selectively infects a subset of nonmaturing BDCA1-positive dendritic cells in human blood, Angela Granelli-Piperno, Irina Shimeliovich, and Margit D. Witmer-Pack
A Dominant Complement Fixation Pathway for Pneumococcal Polysaccharides Initiated by SIGN-R1 Interacting with C1q, Youngsun Kang, Yoonkyung Do, and Haekyung Lee
Immunogenicity and efficacy of immunodeficiency virus-like particles pseudotyped with the G protein of vesicular stomatitis virus, Seraphin Kuate, Christiane P. Stahl-Hennig, and Heribert Stoiber
APOBEC3G/3F mediates intrinsic resistance of monocyte-derived dendritic cells to HIV-1 infection, Marjorie Pion, Angela Granelli-Piperno, and Bastein Mangeat
Intensified and protective CD4+ T cell immunity in mice with anti-dendritic cell HIV gag fusion antibody vaccine, Christine Trumpfheller, Jennifer S. Finke, and Carolina B. López
Effective expansion of alloantigen-specific Foxp3+ CD25 + CD4+ regulatory T cells by dendritic cells during the mixed leukocyte reaction, Sayuri Yamazaki, Munjal P. Patel, and Alice D. Harper
Submissions from 2005
Inducible ablation of mouse Langerhans cells diminishes but fails to abrogate contact hypersensitivity, Clare L. Bennett, Erwin Van Rijn, and Steffen Jung
Sustained expansion of NKT cells and antigen-specific T cells after injection of α-galactosyl-ceramide loaded mature dendritic cells in cancer patients, David H. Chang, Keren Osman, and John E. Connolly
Selective blockade of inhibitory Fcγ receptor enables human dendritic cell maturation with IL-12p70 production and immunity to antibody-coated tumor cells, Madhav V. Dhodapkar, Jacob L. Kaufman, and Marc Ehlers
Network of dendritic cells within the muscular layer of the mouse intestine, Adriana Flores-Langarica, Selene Meza-Pérez, and Juana Calderón-Amador
Dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin/CD209 is abundant on macrophages in the normal human lymph node and is not required for dendritic cell stimulation of the mixed leukocyte reaction, Angela Granelli-Piperno, Alla Pritsker, and Margit D. Witmer-Pack
Innate NKT lymphocytes confer superior adaptive immunity via tumor-capturing dendritic cells, Kang Z. Liu, Juliana Idoyaga, and Anna Charalambous
Increase in TNF-α and inducible nitric oxide synthase-expressing dendritic cells in psoriasis and reduction with efalizumab (anti-CD11a), Michelle A. Lowes, Francesca N. Chamian, and Maria Veronica Abello
Dendritic cell maturation by innate lymphocytes: Coordinated stimulation of innate and adaptive immunity, Christian Münz, Ralph M. Steinman, and Shinichiro Fujii
Association of SIGNR1 with TLR4-MD-2 enhances signal transduction by recognition of LPS in gram-negative bacteria, Kojii Nagaoka, Kazuhiko Takahara, and Kay Tanaka
Research on human subjects in the JEM, Ralph M. Steinman
Submissions from 2004
In Vivo Targeting of Antigens to Maturing Dendritic Cells via the DEC-205 Receptor Improves T Cell Vaccination, Laura C. Bonifaz, David P. Bonnyay, and Anna Charalambous
The linkage of innate to adaptive immunity via maturing dendritic cells in vivo requires CD40 ligation in addition to antigen presentation and CD80/86 costimulation, Shinichiro Fujii, Kang Z. Liu, and Carol L. Smith
High and low affinity carbohydrate ligands revealed for murine SIGN-R1 by carbohydrate array and cell binding approaches, and differing specificities for SIGN-R3 and langerin, Christine Galustian, Chaegyu Park, and Wengang Chai
HIV-1-infected monocyte-derived dendritic cells do not undergo maturation but can elicit IL-10 production and T cell regulation, Angela Granelli-Piperno, Angelika Golebiowska, and Christine Trumpfheller
The C-type lectin SIGN-R1 mediates uptake of the capsular polysaccharide of Streptococcus pneumoniae in the marginal zone of mouse spleen, Youngsun Kang, Jae Y. Kim, and Sandra A. Bruening
The JEM and the JCB: A synergistic partnership, Ralph M. Steinman and Ira S. Mellman
Functional comparison of the mouse DC-SIGN, SIGNR1, SIGNR3 and Langerin, C-type lectins, Kazuhiko Takahara, Yusuke Yashima, and Yoshiki Omatsu
CD25+ CD4+ T cells, expanded with dendritic cells presenting a single autoantigenic peptide, suppress autoimmune diabetes, Kristin V. Tarbell, Sayuri Yamazaki, and Kara D. Olson
Early protection against pathogenic virus infection at a mucosal challenge site after vaccination with attenuated simian immunodeficiency virus, Klara Tenner-Ràcz, Christiane Stahl Hennig, and Klaus T. Überla
Submissions from 2003
Dendritic Cells Initiate Immune Control of Epstein-Barr Virus Transformation of B Lymphocytes in Vitro, Kara L. Bickham, Kiera Goodman, and Casper Paludan
Efficient targeting of protein antigen to the dendritic cell receptor DEC-205 in the steady state leads to antigen presentation on major histocompatibility complex class I products and peripheral CD8+ T cell tolerance, Laura C. Bonifaz, David P. Bonnyay, and Karsten Mahnke
Influenza virus-induced dendritic cell maturation is associated with the induction of strong T cell immunity to a coadministered, normally nonimmunogenic protein, Marie K. Brimnes, Laura C. Bonifaz, Ralph M. Steinman, and Thomas M. Moran
Activation of natural killer T cells by α-galactosylceramide rapidly induces the full maturation of dendritic cells in vivo and thereby acts as an adjuvant for combined CD4 and CD8 T cell immunity to a coadministered protein, Shinichiro Fujii, Kanako Shimizu, and Carol L. Smith
Dendritic Cells Charged with Apoptotic Tumor Cells Induce Long-Lived Protective CD4+ and CD8+ T Cell Immunity against B16 Melanoma, Romina S. Goldszmid, Juliana Idoyaga, and Alicia Inès Bravo
SIGN-R1, a novel C-type lectin expressed by marginal zone macrophages in spleen, mediates uptake of the polysaccharide dextran, Youngsun Kang, Sayuri Yamazaki, and Tomonori Iyoda
Macrophages control the retention and trafficking of B lymphocytes in the splenic marginal zone, Mikael Karlsson, Rodolphe Renè Guinamard, and Silvia M. Bolland
Lipopolysaccharide or Whole Bacteria Block the Conversion of Inflammatory Monocytes into Dendritic Cells In Vivo, Gianluca Rotta, Emmerson W. Edwards, and Sabina Sangaletti
Tolerogenic dendritic cells, Ralph M. Steinman, Daniel Hawiger, and Michel C. Nussenzweig
DC-SIGN (CD209) mediates dengue virus infection of human dendritic cells, Boonrat Tassaneetrithep, Timothy H. Burgess, and Angela Granelli-Piperno
Cell type-dependent retention and transmission of HIV-1 by DC-SIGN, Christine Trumpfheller, Chaegyu Park, and Jennifer S. Finke
Direct expansion of functional CD25+ CD4+ regulatory T cells by antigen-processing dendritic cells, Sayuri Yarmazaki, Sayuri Yamazaki, Tomonori Iyoda, and Kristin V. Tarbell
Submissions from 2002
Expression of a functional eotaxin (CC chemokine ligand 11) receptor CCR3 by human dendritic cells, Sylvia Beaulieu, Davide E. Robbiani, and Xixuan Du
Human dendritic cells activate resting natural killer (NK) cells and are recognized via the NKp30 receptor by activated NK cells, Guido Ferlazzo, Mingli Tsang, and Lorenzo Moretta
Increased macrophage infection upon subcutaneous inoculation of rhesus macaques with simian immunodeficiency virus-loaded dendritic cells or T cells but not with cell-free virus, Ralf Ignatius, Klara Tenner-Ràcz, and Davorka Messmer
The CD8+ dendritic cell subset selectively endocytoses dying cells in culture and in vivo, Tomonori Iyoda, Susumu Shimoyama, and Kang Z. Liu
Immune tolerance after delivery of dying cells to dendritic cells in situ, Kang Z. Liu, Tomonori Iyoda, and Marzena Saternus
Preparation of clinical-grade recombinant canarypox-human immunodeficiency virus vaccine-loaded human dendritic cells, Mary A. Marovich, John R. Mascola, and Michael A. Eller
Endogenously expressed nef uncouples cytokine and chemokine production from membrane phenotypic maturation in dendritic cells, Davorka Messmer and Jean M. Jacqué
The simian immunodeficiency virus Δnef vaccine, after application to the tonsils of rhesus macaques, replicates primarily within CD4+ T cells and elicits a local perforin-positive CD8+ T-cell response, Christiane P. Stahl-Hennig, Ralph M. Steinman, and Peter Ten Haaft
Avoiding horror autotoxicus: The importance of dendritic cells in peripheral T cell tolerance, Ralph M. Steinman and Michel C. Nussenzweig
Exploiting dendritic cells to improve vaccine efficacy, Ralph M. Steinman and Melissa Pope
Identification and expression of mouse Langerin (CD207) in dendritic cells, Kazuhiko Takahara, Yoshiki Omatsu, and Yusuke Yashima
Submissions from 2001
EBNA1-specific CD4+ T cells in healthy carriers of Epstein-Barr virus are primarily Th1 in function, Kara L. Bickham, Christian Münz, and Mingli Tsang