Date of Award
Doctor of Philosophy (PhD)
Unstable prokaryotic strains arise occasionally under a variety of circumstances and with a variety of properties which make them amenable to genetic and physiological analysis at different levels of precision. A review of a number of such unstable systems, initially identified on the basis of a regular segregation to phenotypically non-parental types, has led to the recognition of a series of criteria for the systematic analysis of such strains. These criteria are applied to a sulfanilamideresistant mutant of pneumococcus which regularly segregates to strains sensitive to sulfanilamide and resistant to p-nitrobenzoic acid, another analogue of paraminobenzoic acid.
Ledbetter, Mary Lee Stewart, "Properties of the Merozygotes Associated with a Sulfonamide-Resistant Mutation in Pneumococcus" (1972). Student Theses and Dissertations. 544.