Student Theses and Dissertations

Date of Award


Document Type


Degree Name

Doctor of Philosophy (PhD)

RU Laboratory

Bronk Laboratory


Unstable prokaryotic strains arise occasionally under a variety of circumstances and with a variety of properties which make them amenable to genetic and physiological analysis at different levels of precision. A review of a number of such unstable systems, initially identified on the basis of a regular segregation to phenotypically non-parental types, has led to the recognition of a series of criteria for the systematic analysis of such strains. These criteria are applied to a sulfanilamideresistant mutant of pneumococcus which regularly segregates to strains sensitive to sulfanilamide and resistant to p-nitrobenzoic acid, another analogue of paraminobenzoic acid.


A thesis submitted to the Faculty of The Rockefeller University in partial fulfillment of the requirements for the degree of Doctor of Philosophy

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Life Sciences Commons