Properties of the Merozygotes Associated with a Sulfonamide-Resistant Mutation in Pneumococcus

Author

Mary Lee Stewart Ledbetter

Date of Award

1972

Document Type

Thesis

Degree Name

Doctor of Philosophy (PhD)

Thesis Advisor

Rollin Hotchkiss

Abstract

Unstable prokaryotic strains arise occasionally under a variety of circumstances and with a variety of properties which make them amenable to genetic and physiological analysis at different levels of precision. A review of a number of such unstable systems, initially identified on the basis of a regular segregation to phenotypically non-parental types, has led to the recognition of a series of criteria for the systematic analysis of such strains. These criteria are applied to a sulfanilamideresistant mutant of pneumococcus which regularly segregates to strains sensitive to sulfanilamide and resistant to p-nitrobenzoic acid, another analogue of paraminobenzoic acid.

Comments

A thesis presented to the faculty of The Rockefeller University in partial fulfillment of the requirements for the degree of Doctor of Philosophy

Recommended Citation

Ledbetter, Mary Lee Stewart, "Properties of the Merozygotes Associated with a Sulfonamide-Resistant Mutation in Pneumococcus" (1972). Student Theses and Dissertations. 544.
https://digitalcommons.rockefeller.edu/student_theses_and_dissertations/544