Investigating the Supracellular Processes Underlying Emergent Material Phase Properties During Embryonic Skin Morphogenesis

Author

Karl H. Palmquist

Date of Award

2024

Document Type

Thesis

Degree Name

Doctor of Philosophy (PhD)

Abstract

During embryonic development, vertebrate tissues are sculpted by the coordinated behaviors of cells.Vertebrate organs are complex, typically requiring the orchestrated dynamics of hundreds to thousands of cells. Yet, due to their functional significance, the mechanisms underlying organ formation are robust.This implies the need for mechanisms to constrain critical processes during embryogenesis. While much of developmental biology has focused on the aspects of self-organization that relate to patterns of chemicals and molecules across a tissue and their relationship to gene regulatory networks, less attention has been given to the physical mechanisms at play. In particular,it is poorly understood how, in complex tissues, cells self-organize in a robust manner.

Comments

A Thesis Presented to the Faculty of The Rockefeller University in Partial Fulfillment of the Requirements for the degree of Doctor of Philosophy

Recommended Citation

Palmquist, Karl H., "Investigating the Supracellular Processes Underlying Emergent Material Phase Properties During Embryonic Skin Morphogenesis" (2024). Student Theses and Dissertations. 771.
https://digitalcommons.rockefeller.edu/student_theses_and_dissertations/771