Date of Award
Doctor of Philosophy (PhD)
Transformation of cells by Rous Sarcoma virus results from the action of a single virally coded phosphoprotein with a molecular weight of 60,000 daltons (pp60SRC). The expression of pp60SRCresults in many significant changes in the cell's phenotype which include disruption of the cytoskeleton and the deregulation of cell growth.
Greenberg, Michael E., "Purification and Activity of the PP60SRC Protein Kinase" (1982). Student Theses and Dissertations. 587.