Purification and Activity of the PP60SRC Protein Kinase

Author

Michael E. Greenberg

Date of Award

1982

Document Type

Thesis

Degree Name

Doctor of Philosophy (PhD)

RU Laboratory

Edelman-Cunningham Laboratory

Abstract

Transformation of cells by Rous Sarcoma virus results from the action of a single virally coded phosphoprotein with a molecular weight of 60,000 daltons (pp60^SRC). The expression of pp60^SRCresults in many significant changes in the cell's phenotype which include disruption of the cytoskeleton and the deregulation of cell growth.

Comments

A thesis submitted to the Faculty of The Rockefeller University in partial fulfillment of the requirements for the degree of Doctor of Philosophy

Recommended Citation

Greenberg, Michael E., "Purification and Activity of the PP60SRC Protein Kinase" (1982). Student Theses and Dissertations. 587.
https://digitalcommons.rockefeller.edu/student_theses_and_dissertations/587