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Home > Oral History Collection > THE-MARKUS-LIBRARY-ORAL-HISTORY-PROJECT > SARAH-SCHLESINGER

Sarah J. Schlesinger Oral History

 

Dr. Schlesinger chairs The Rockefeller University Institutional Review Board and the research education and training committee, which is part of the Center for Clinical and Translational Science. She also serves as director of the Clinical Scholars Program and the Certificate in Clinical and Translational Sciences Program.

Previously, Dr. Schlesinger was involved in clinical trials of 11 HIV vaccines and vaccine adjuvants. She is now conducting the first HIV vaccine trial based on dendritic cells, which were discovered at Rockefeller in 1973 by Ralph M. Steinman and his mentor, Zanvil A. Cohn.

In the steady state, dendritic cells capture antigens and travel to immune or lymphoid tissues, where they present the antigens to T cells, stimulating a robust immune response. But dendritic cells also play a seemingly opposite role, immune tolerance, silencing dangerous immune cells and preventing them from attacking the body’s own tissues. Working with Steinman, Dr. Schlesinger used dendritic cells to study and design treatments that can either enhance the immune system or silence its functions in an antigen- or disease-specific manner.

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  • Sarah J. Schlesinger Oral History. Part 1: Family of great expectations by The Rockefeller University

    Sarah J. Schlesinger Oral History. Part 1: Family of great expectations

  • Sarah J. Schlesinger Oral History. Part2: From Holiday Lecture to Steinman's laboratory by The Rockefeller University

    Sarah J. Schlesinger Oral History. Part2: From Holiday Lecture to Steinman's laboratory

  • Sarah J. Schlesinger Oral History. Part 3: Dendritic cells by The Rockefeller University

    Sarah J. Schlesinger Oral History. Part 3: Dendritic cells

  • Sarah J. Schlesinger Oral History. Part 4: Remembering Dr. Zanvil Cohn by The Rockefeller University

    Sarah J. Schlesinger Oral History. Part 4: Remembering Dr. Zanvil Cohn

  • Sarah J. Schlesinger Oral History. Part 5: Getting M.D. by The Rockefeller University

    Sarah J. Schlesinger Oral History. Part 5: Getting M.D.

  • Sarah J. Schlesinger Oral History. Part 6: Building career and family by The Rockefeller University

    Sarah J. Schlesinger Oral History. Part 6: Building career and family

  • Sarah J. Schlesinger Oral History. Part 7: Clinical development by The Rockefeller University

    Sarah J. Schlesinger Oral History. Part 7: Clinical development

  • Sarah J. Schlesinger Oral History. Part 8: Experimental treatment for Dr. Steinman by The Rockefeller University

    Sarah J. Schlesinger Oral History. Part 8: Experimental treatment for Dr. Steinman

  • Sarah J. Schlesinger Oral History. Part 9: Nobel Prize by The Rockefeller University

    Sarah J. Schlesinger Oral History. Part 9: Nobel Prize

  • Sarah J. Schlesinger Oral History. Part 10: Current work by The Rockefeller University

    Sarah J. Schlesinger Oral History. Part 10: Current work

  • Sarah J. Schlesinger Oral History. Part 11: Advice to young scientists by The Rockefeller University

    Sarah J. Schlesinger Oral History. Part 11: Advice to young scientists

 
 
 

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