Krause, R./Editor Antibodies in human diagnosis and therapy

Title

Krause, R./Editor Antibodies in human diagnosis and therapy

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Description

Edgar Haber, Richard M. Kraus/editors. Antibodies in human diagnosis and therapy

The purpose of this volume is to provide a summary of the current state of knowledge of the structure of the antigen combining site, approaches to the synthesis of antibodies by chemical and biological means, and their application in human therapy. The covalent structure of the antibody combining site is analyzed in relation to the specificity of the antigen which it binds. The available three-dimensional models of combining sites are presented showing detailed mechanisms of antigen binding at an atomic level. The concept of the chemical synthesis of antibodies is critically addressed and evaluated as a potential future method for the manufacture of antibodies for therapeutic and diagnostic use.

The authors of this volume include fundamental investigators in the field of immunoglobulin structure, X-ray crystallographers, peptide synthetic chemists, cellular immunologists, and clinical investigators. They combine their diverse interests to give the reader a fascinating glimpse into an exciting and rapidly developing field.


ISBN

0890040893

Publication Date

1975

Publisher

Raven Press

City

New York

Keywords

antibodies, immunoglobulins, immunotherapy

Comments

The Rockefeller University Library 3rd Floor Special Collections QW 570 H114 1975

The Rockefeller University Library President's Office OFFICE OF THE PRESIDENT

Krause, R./Editor Antibodies in human diagnosis and therapy

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