Preview
Creation Date
3-2022
Description
Dr. Merrifield’s drum program for peptide synthesizer, early 1960s
Bruce Merrifield (1921-2006) joined the Rockefeller Institute in 1949 where he started to work as an assistant for Dr. D. W. Woolley. They worked on a dinucleotide growth factor Merrifield discovered in graduate school and on peptide growth factor that Woolley had discovered earlier. These studies led to the need for peptide synthesis and, eventually, to the ideal for solid-phase peptide synthesis in 1959 (in 1984 Bruce Merrifield won the Nobel Prize in Chemistry for this invention). In 1963 Dr. Merrifield was a sole author of a classic paper in the Journal of the American Chemical Society in which the reported a method he called solid-phase peptide synthesis.
Keywords
exhibit, library, Bruce Merrifield, peptide synthesizer