Liver Cell Adhesion Molecules in Embryonic Development

Author

Warren J. Gallin

Date of Award

1983

Document Type

Thesis

Degree Name

Doctor of Philosophy (PhD)

RU Laboratory

Edelman-Cunningham Laboratory

Abstract

Cell-cell adhesion is one of the essential processes for normal embryogenesis. The isolation and characterization of the neural cell adhesion molecule, N-CAM, provided the first substantial opportunity to study this process at a molecular level. Moreover, studies of N-CAM expression in embryos suggested that cell adhesion molecules may play a critical role in induction. This thesis describes the isolation of a glycoprotein, L-CAM, that mediates adhesion between liver cells, using an assay similar to the one used to isolate N-CAM.

Comments

A thesis submitted to the Faculty of The Rockefeller University in partial fulfillment of the requirements for the degree of Doctor of Philosophy

Recommended Citation

Gallin, Warren J., "Liver Cell Adhesion Molecules in Embryonic Development" (1983). Student Theses and Dissertations. 605.
https://digitalcommons.rockefeller.edu/student_theses_and_dissertations/605