Date of Award
Doctor of Philosophy (PhD)
An in vitro incubation system which allows the labeling and isolation of secretion granules - and their subsequent resolution into membrane and content subfractions - has been developed by using dissected lobules of rabbit parotid glands. The system can be used to study a series of aspects related to the last phases of the secretory cycle (concentration, storage, discharge). The work reported in this thesis characterizes the system and presents data concerning the relative rates of synthesis of membrane and content proteins.
Castle, John David, "Studies on the Secretory Process of Rabbit Parotid" (1973). Student Theses and Dissertations. 537.