Student Theses and Dissertations

Date of Award


Document Type


Degree Name

Doctor of Philosophy (PhD)

RU Laboratory

Bronk Laboratory


An in vitro incubation system which allows the labeling and isolation of secretion granules - and their subsequent resolution into membrane and content subfractions - has been developed by using dissected lobules of rabbit parotid glands. The system can be used to study a series of aspects related to the last phases of the secretory cycle (concentration, storage, discharge). The work reported in this thesis characterizes the system and presents data concerning the relative rates of synthesis of membrane and content proteins.


A thesis submitted to the Faculty of The Rockefeller University in partial fulfillment of the requirements for the degree of Doctor of Philosophy

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Life Sciences Commons