Woolley in the lab at the Rockefeller Institute, 1947
Among Woolley's achievements was his pioneering use of microbes to isolate and characterize vitamins and growth factors. His studies concerning the use of antimetabolites to trace unknown metabolic disorders in animals and man were his essential contribution and are brought together in his book A Study of Antimetabolites. Woolley's later prophetic studies of serotonin and its receptor sites in relation to hypertension and mental illness paved the way for the study of psychosis on a biochemical basis.
Member of the scientific staff of The Rockefeller from 1939 until his death in 1966, Dr. Woolley was one of the "most gifted and creative individuals" (Henry N. Wood)
Wayne Woolley, metabolic disoders, serotonin