Studies on the Structure of Human Fibronectin

Author

Martha B. Furie

Date of Award

1980

Document Type

Thesis

Degree Name

Doctor of Philosophy (PhD)

RU Laboratory

Rifkin Laboratory

Abstract

Plasma fibronectin is a glycoprotein that consists of two polypeptide chains of approximately 250,000 and 245,000 daltons, joined by disulfide bonds located near one end of the molecule. Fibronectin was isolated from human plasma by gelatin-agarose affinity chromatography and DEAE-cellulose ion exchange chromatography. The two subunit chains were found to be similar or identical with respect to primary structure, using a one-dimensional peptide mapping technique.

Comments

A thesis submitted to the Faculty of The Rockefeller University in partial fulfillment of the requirements for the degree of Doctor of Philosophy

Recommended Citation

Furie, Martha B., "Studies on the Structure of Human Fibronectin" (1980). Student Theses and Dissertations. 477.
https://digitalcommons.rockefeller.edu/student_theses_and_dissertations/477