Rat Lymphocyte Surface Glycoproteins Mediating Mitogenesis by Periodate or Neuraminidase Plus Galactose Oxidase

Author

Richard Neal Mitchell

Date of Award

1980

Document Type

Thesis

Degree Name

Doctor of Philosophy (PhD)

RU Laboratory

deDuve Laboratory

Abstract

The objectives of this thesis work involved the identification and characterization of rat lymphocyte surface components involved in mitogenic stimulation by the oxidative agents periodate and neuraminidase plus galactose oxidase (NGO). Lymph node cell blastogenesis induced by these oxidative agents was inhibited by reduction with borohydride or reaction with cysteine methyl ester (CME) without affecting the ability of lymph node cells (LNC) to respond to concanavalin A (Con A).

Comments

A thesis submitted to the Faculty of The Rockefeller University in partial fulfillment of the requirements for the degree of Doctor of Philosophy

Recommended Citation

Mitchell, Richard Neal, "Rat Lymphocyte Surface Glycoproteins Mediating Mitogenesis by Periodate or Neuraminidase Plus Galactose Oxidase" (1980). Student Theses and Dissertations. 475.
https://digitalcommons.rockefeller.edu/student_theses_and_dissertations/475