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Submissions from 2000

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Dendritic cells at a DNA vaccination site express the encoded influenza nucleoprotein and prime MHC class I-restricted cytolytic lymphocytes upon adoptive transfer, Adrian I. Bot, Alexandru C. Stan, and Kayo Inaba

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Calcitonin gene-related peptide decreases expression of HLA-DR and CD86 by human dendritic cells and dampens dendritic cell-driven T cell- proliferative responses via the type I calcitonin gene-related peptide receptor, John A. Carucci, Ralf Ignatius, and Yang Wei

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Mature dendritic cells boost functionally superior CD8+ T-cell in humans without foreign helper epitopes, Madhav V. Dhodapkar, Joseph Krasovsky, Ralph M. Steinman, and Nina Bhardwaj

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The formation of immunogenic major histocompatibility complex class II-peptide ligands in lysosomal compartments of dendritic cells is regulated by inflammatory stimuli, Kayo Inaba, Shannon J. Turley, and Tomonori Iyoda

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The decreased replicative capacity of simian immunodeficiency virus SIVmac239Δnef is manifest in cultures of immature dendritic cells and T cells, Davorka Messmer, Ralf Ignatius, and Christine Santisteban

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Human CD4+ T lymphocytes consistently respond to the latent Epstein- Barr virus nuclear antigen EBNA1, Christian Münz, Kara L. Bickham, and Marion S. Subklewe

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DC-SIGN: A guide to some mysteries of dendritic cells, Ralph M. Steinman

Submissions from 1999

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TRANCE, a tumor necrosis factor family member critical for CD40 ligand- independent T helper cell activation, Martin F. Bachmann, Brian R. Wong, and Régis Josien

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Rapid generation of broad T-cell immunity in humans after a single injection of mature dendritic cells, Madhav V. Dhodapkar, Ralph M. Steinman, and Mark Sapp

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Virus replication begins in dendritic cells during the transmission of HIV-1 from mature dendritic cells to T cells, Angela Granelli-Piperno, Victoria Finkel, Elena Delgado, and Ralph M. Steinman

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Differentiation of phagocytic monocytes into lymph node dendritic cells in vivo, Gwendalyn J. Randolph, Kayo Inaba, and Davide E. Robbiani

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Vaccination with Mage-3A1 peptide-pulsed nature, monocyte-derived dendritic cells expands specific cytotoxic T cells and induces regression of some metastases in advanced stage IV melanoma, Beatrice Thurner, Ina Haendle, and Claudia Röder

Submissions from 1998

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Neutralizing monoclonal antibodies block human immunodeficiency virus type 1 infection of dendritic cells and transmission to T cells, Sarah Frankel, Ralph M. Steinman, and Nelson L. Michael

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Immature dendritic cells selectively replicate macrophagetropic (M- tropic) human immunodeficiency virus type 1, while mature cells efficiently transmit both M- and T-tropic virus to T cells, Angela Granelli-Piperno, Elena Delgado, and Victoria Finkel

Efficient presentation of phagocytosed cellular fragments on the major histocompatibility complex class II products of dendritic cells, Kayo Inaba, Shannon J. Turley, and Fumiya Yamaide

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A physiologic function for p-glycoprotein (MDR-1) during the migration of dendritic cells from skin via afferent lymphatic vessels, Gwendalyn J. Randolph, Sylvia Beaulieu, and Melissa Pope

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The unenlarged lymph nodes of HIV-1-infected, asymptomatic patients with high CD4 T cell counts are sites for virus replication and CD4 T cell proliferation. The impact of highly active antiretroviral therapy, Klara Tenner-Racz, Hans Jürgen Stellbrink, and Jan van Lunzen

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The TRAF family of signal transducers mediates NF-κB activation by the TRANCE receptor, Brian R. Wong, Régis Josien, and Soo-Young Lee

Submissions from 1997

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High levels of a major histocompatibility complex II-self peptide complex on dendritic cells from the T cell areas of lymph nodes, Kayo Inaba, Margit D. Witmer-Pack, and Muneo M. Inaba

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Dendritic cells as adjuvants for immune-mediated resistance to tumors, Gerold Schuler and Ralph M. Steinman

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TRANCE (Tumor necrosis factor [TNF]-related Activation-induced Cytokine), a new TNF family member predominantly expressed in t cells, is a dendritic cell-specific survival factor, Brian R. Wong, Régis Josien, and Soo-Young Lee

Submissions from 1996

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Efficient interaction of HIV-1 with purified dendritic cells via multiple chemokine coreceptors, Angela Granelli-Piperno, Bernard Moser, and Melissa Pope

Submissions from 1995

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Coexpression of NF-κB/Rel and Sp1 transcription factors in human immunodeficiency virus 1-induced, dendritic cell-T-cell syncytia, Angela Granelli-Piperno, Melissa Pope, Kayo Inaba, and Ralph M. Steinman

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Both dendritic cells and memory T lymphocytes emigrate from organ cultures of human skin and form distinctive dendritic-T-cell conjugates, Melissa Pope, Michael G.H. Betjes, and Haideh Hirman

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Low levels of HIV-1 infection in cutaneous dendritic cells promote extensive viral replication upon binding to memory CD4+ T cells, Melissa Pope, Stuart Gezelter, and Nancy Gallo

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The endoeytie activity of dendritic cells, Ralph M. Steinman and Joel A. Swanson

Submissions from 1994

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Influenza virus-infected dendritic cells stimulate strong proliferative and cytolytic responses from human CD8+ T cells, Nina Bhardwaj, Armin Bender, and Noemi Gonzalez

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The Tissue Distribution of the B7-2 Costimulator in Mice: Abundant Expression on Dendritic Cells In Situ and During Maturation In Vitro, Kayo Inaba, Margit D. Witmer-Pack, and Muneo M. Inaba

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Proliferating dendritic cell progenitors in human blood, Nikolaus Romani, Stefan Gruner, and Daniela Brang

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Zanvil Alexander Cohn 1926-1993, Ralph M. Steinman and Carol L. Moberg

Submissions from 1993

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Small amounts of superantigen, when presented on dendritic cells, are sufficient to initiate T cell responses, Nina Bhardwaj, James W. Young, and Anahid J. Nisanian

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Efficient loading of identical viral peptide onto class II molecules by antigenized immunoglobulin and influenza virus, Teodor D. Brumeanu, Ralph M. Steinman, and William J. Swiggard

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Granulocytes, macrophages, and dendritic cells arise from a common major histocompatibility complex class II-negative progenitor in mouse bone marrow, Kayo Inaba, Muneo M. Inaba, and Masashi Deguchi

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Dendritic cell progenitors phagocytose particulates, including bacillus calmette-guerin organisms, and sensitize mice to mycobacterial antigens in vivo, Kayo Inaba, Muneo M. Inaba, and Makoto Naito

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Dendritic cells freshly isolated from human blood express CD4 and mature into typical immtmostimulatory dendritic cells after culture in monocyte-conditioned medium, Una O'doherty, Ralph M. Steinman, and Michael Peng

Submissions from 1992

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Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor, Kayo Inaba, Muneo M. Inaba, and Nikolaus Romani

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Identification of proliferating dendritic cell precursors in mouse blood, Kayo Inaba, Ralph M. Steinman, and Margit D. Witmer-Pack

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Mechanisms of mouse spleen dendritic cell function in the generation of influenza-specific, cytolytic T lymphocytes, Rita Nonacs, Cornelia Humborg, James P. Tam, and Ralph M. Steinman

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The B7/BB1 antigen provides one of several costimulatory signals for the activation of CD4+ T lymphocytes by human blood dendritic cells in vitro, James W. Young, Lydia Koulova, and Steve A. Soergel

Submissions from 1991

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Latent HIV-1 infection in enriched populations of blood monocytes and T cells from seropositive patients, Margaret J. McElrath, Ralph M. Steinman, and Zanvil A. Cohn

Submissions from 1990

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Dendritic cells are the principal cells in mouse spleen bearing immunogenic fragments of foreign proteins, Mary T. Crowley, Kayo Inaba, and Ralph M. Steinman

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The distinct surface of human blood dendritic cells, as observed after an improved isolation method, Peter S. Freudenthal and Ralph M. Steinman

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The Effect of Immunosuppressive Agents on the Induction of Nuclear Factors that Bind to Sites on the Interleukin 2 Promoter, Angela Granelli-Piperno, Patricia Nolan, Kayo Inaba, and Ralph M. Steinman

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Dendritic cells pulsed with protein antigens in vitro can prime antigen-specific, MHC-restricted T cells in situ, Kayo Inaba, Joshua P. Metlay, Mary T. Crowley, and Ralph M. Steinman

Migration and maturation of langerhans cells in skin transplants and explants, Christian P. Larsen, Ralph M. Steinman, and Margit D. Witmer-Pack

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The distinct leukocyte integrins of mouse spleen dendritic cells as identified with new hamster monoclonal antibodies, Joshua P. Metlay, Margit D. Witmer-Pack, and Ralf Agger

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Antigen processing by epidermal langerhans cells correlates with the level of biosynthesis of major histocompatibility complex class II molecules and expression of invariant chain, Ellen Puré, Kayo Inaba, and Mary T. Crowley

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Dendritic cells stimulate primary human cytolytic lymphocyte responses in the absence of CD4+ helper T cells, James W. Young and Ralph M. Steinman

Submissions from 1989

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Interleukin 1 production during accessory cell-dependent mitogenesis of T lymphocytes, Nina Bharwaj, Lisa L. Lau, and Steven M. Friedman

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Macrophages phagocytose thymic lymphocytes with productively rearranged T cell receptor α and β genes, Kayo Inaba, Muneo M. Inaba, and Tatsuo Kinashi

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An antigen-independent contact mechanism as an early step in T cell-proliferative responses to dendritic cells, Kayo Inaba, Nikolaus Romani, and Ralph M. Steinman

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Most CD4+ T cells from human immunodeficiency virus-1 infected patients can undergo prolonged clonal expansion, Erik G. Langhoff, Margaret J. McElrath, and Harm J. Bos

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Clonal expansion of human T lymphocytes initiated by dendritic cells, Erik G. Langhoff and Ralph M. Steinman

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Distinct features of dendritic cells and anti-Ig activated B cells as stimulators of the primary mixed leukocyte reaction, Joshua P. Metlay and Ellen Puré

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Presentation of exogenous protein antigens by dendritic cells to T cell clones. Intact protein is presented best by immature, epidermal Langerhans cells, Nikolaus Romani, Sumil Koide, and Mary T. Crowley

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A small number of anti-CD3 molecules on dendritic cells stimulate DNA synthesis in mouse T lymphocytes, Nikolaus Romani, Ellen Puré, and Kayo Inaba

Submissions from 1988

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Identification of a 24-kDa cytokine that is required for development of cytolytic T lymphocytes, Cristina Cernetti, Ralph M. Steinman, and Angela Granelli-Piperno

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The immunological and infectious sequelae of the acquired immune deficiency syndrome, Zanvil A. Cohn and Ralph M. Steinman

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The function of Ia+ dendritic cells and ia dendritic cell precursors in thymocyte mitogenesis to lectin and lectin plus interleukin i, Kayo Inaba, Margit D. Witmer-Pack, and Muneo M. Inaba

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Induction of interleukin lα mrna during the antigen-dependent interaction of sensitized t lymphoblasts with macrophages, Sumil Koide and Ralph M. Steinman

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Unusual phenotype of B cells in the thymus of normal mice, Muneo Miyama-Inaba, Shoichi Kuma, and Kayo Inaba

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Properties of isolated red pulp macrophages from mouse spleen, Asma R. Nusrat, Samuel D. Wright, and Alan A. Aderem

Submissions from 1987

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Monoclonal antibodies to LFA-1 and TO CD4 inhibit the mixed leukocyte reaction after the antigen-dependent clustering of dendritic cells and T lymphocytes, Kayo Inaba and Ralph M. Steinman

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Direct activation of CD8+ cytotoxic T lymphocytes by dendritic cells, Kayo Inaba, James W. Young, and Ralph M. Steinman

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Interleukin 1 enhances T-dependent immune responses by amplifying the function of dendritic cells, Sumil Koide, Kayo Inaba, and Ralph M. Steinman

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Induction of murine interleukin 1: Stimuli and responsive primary cells, Sumil Koide and Ralph M. Steinman

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Granulocyte/macrophage colony-stimulating factor is essential for the viability and function of cultured murine epidermal langerhans cells, Margit D. Witmer-Pack, Wendy A. Olivier, and Jay E. Valinsky

Submissions from 1986

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Lymphokine and nonlymphokine mRNA levels in stimulated human T cells: Kinetics, mitogen requirements, and effects of cyclosporin a, Angela Granelli-Piperno, Linda Andrus, and Ralph M. Steinman

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Immunologic properties of purified epidermal langerhans cells: Distinct requirements for stimulation of unprimed and sensitized T lymphocytes, Kayo Inaba, Gerold Schuler, and Margit D. Witmer

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Accessory cell-T lymphocyte interactions. antigen-dependent and -independent clustering, Kayo Inaba and Ralph M. Steinman

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Influence of delayed immune reactions on human epidermal keratinocytes, Gilla Kaplan, Margit D. Witmer, and Indira V. Nath

Submissions from 1985

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Properties of memory T lymphocytes isolated from the mixed leukocyte reaction, Kayo Inaba, Sumil Koide, and Ralph M. Steinman

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An analysis of in vitro T cell responsiveness in lepromatous leprosy, Gilla Kaplan, David E. Weinstein, and Ralph M. Steinman

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Murine kupffer cells: Mononuclear phagocytes deficient in the generation of reactive oxygen intermediates, David A. Lepay, Carl F. Nathan, and Ralph M. Steinman

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Liver macrophages in murine listeriosis: Cell-mediated immunity is correlated with an influx of macrophages capable o f generating reactive oxygen intermediates, David A. Lepay, Ralph M. Steinman, and Carl F. Nathan

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The thy-1-bearing cell of murine epidermis: A distinctive leukocyte perhaps related to natural killer cells, Nikolaus Romani, Georg Stingl, and Erwin Tschachler

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A comparison of murine epidermal Langerhans cells with spleen dendritic cells, Gerold Schuler, Nikolaus Romani, and Ralph M. Steinman

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Murine epidermal langerhans cells mature into potent immunostimulatory dendritic cells in vitro, Gerold Schuler and Ralph M. Steinman

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Identification of immunostimulatory dendritic cells in the synovial effusions of patients with rheumatoid arthritis, Nathan J. Zvaifler, Ralph M. Steinman, and Gilla Kaplan

Submissions from 1984

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Prevention of rejection of murine islet allografts by pretreatment with anti-dendritic cell antibody, Denise L. Faustman, Ralph M. Steinman, and Howard M. Gebel

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Stimulation of lymphokine release from T lymphoblasts: Requirement for mRNA synthesis and inhibition by cyclosporin A, Angela Granelli-Piperno, Kayo Inaba, and Ralph M. Steinman

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Resting and sensitized T lymphocytes exhibit distinct stimulatory (antigen-presenting cell) requirements for growth and lymphokine release, Kayo Inaba and Ralph M. Steinman

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Clustering of dendritic cells, helper T lymphocytes, and histocompatible B cells during primary antibody responses in vitro, Kayo Inaba, Margit D. Witmer, and Ralph M. Steinman

Submissions from 1983

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Dendritic cells initiate a two-stage mechanism for T lymphocyte proliferation, Jonathan Austyn, Ralph M. Steinman, and David E. Weinstein

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Dendritic cells induce T lymphocytes to release B cell-stimulating factors by an interleukin 2-dependent mechanism, Kayo Inaba, Angela Granelli-Piperno, and Ralph M. Steinman

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Dendritic cells are critical accessory cells for thymus-dependent antibody responses in mouse and in man, Kayo Inaba, Ralph M. Steinman, and Wesley C. Voorhis

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Internalization and degradation of macrophage Fc receptors during receptor-mediated phagocytosis, Ira S. Mellman, Helen Plutner, and Ralph M. Steinman

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Membrane proteins of the vacuolar system. III. Further studies on the composition and recycling of endocytic vacuole membrane in cultured macrophages, William A. Muller

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Defective λ interferon production in leprosy reversal with antigen and interleukin 2, Natalia Nogueira, Gilla Kaplan, and E. Levy

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Accessory cells in Murine Peyer’s patch: I. Identification and enrichment of a functional dendritic cell, David M. Spalding, William J. Koopman, and John H. Eldridge

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Dendritic cells are the principal stimulators of the primary mixed leukocyte reaction in mice, Ralph M. Steinman, Badma Gutchinov, Margit D. Witmer, and Michel C. Nussenzweig

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Endocytosis and the recycling of plasma membrane, Ralph M. Steinman, Ira S. Mellman, William A. Muller, and Zanvil A. Cohn

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Specific antimononuclear phagocyte monoclonal antibodies application to the purification of dendritic cells and the tissue localization of macrophages, Wesley C. Voorhis

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Specific antimononuclear phagocyte monoclonal antibodies application to the purification of dendritic cells and the tissue localization of macrophages, Wesley C. Voorhis, Ralph M. Steinman, and Laura S. Hair

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Relative efficacy of human monocytes and dendritic cells as accessory cells for T cell replication, Wesley C. Voorhis, Jay E. Valinsky, and Eileen Hoffman

Submissions from 1982

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Specialized antigen-presenting cells. Splenic-dendritic cells and peritoneal-exudate cells induced by mycobacteria activate effector T cells that are resistant to suppression, Judith S. Britz, Phillip W. Askenase, W. Ptak, and Ralph M. Steinman

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Intralysosomal accumulation of polyanions. I. Fusion of pinocytic and phagocytic vacuoles with secondary lysosomes, Margaret Carol Kielian, Ralph M. Steinman, and Zanvil A. Cohn

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A monoclonal antibody specific for mouse dendritic cells, Michel C. Nussenzweig, Ralph M. Steinman, Margit D. Witmer, and Badma Gutchinov

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Human dendritic cells. Enrichment and characterization from peripheral blood, Wesley C. Voorhis, Laura S. Hair, Ralph M. Steinman, and Gilla Kaplan

Submissions from 1981

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Studies of the cell surface of mouse dendritic cells and other leukocytes, Michel C. Nussenzweig, Ralph M. Steinman, and Jay C. Unkeless