Digital Commons @ RU

Life on the Edge: Insights into the Neural and Behavioral Algorithms of Plume Tracking, Andrew Siliciano
Student Theses and Dissertations

Interrogation and Manipulation of the IGG FC Glycan, Aaron Keshav Gupta
Student Theses and Dissertations

Structures, Functions, and Druggability of the SARS-CoV-2 Replication–Transcription Complex, Brandon F. Malone
Student Theses and Dissertations

The Search for Regulatory Mutations in Gitelman Syndrome, Renan Eduardo Aparicio
Student Theses and Dissertations

Enrichment and Transcriptome Analysis of CD4+ T Cell Clones Harboring Intact HIV-1 Proviruses, Georg Hartmut Johannes Weymar
Student Theses and Dissertations

On the Origins of Genetic Novelty in Drosophila, Eric Bo Zheng
Student Theses and Dissertations

Inter-Organellar Nucleic Acid Communication by a Mitochondrial tRNA Regulates Nuclear Transcription, Christopher Rouya
Student Theses and Dissertations

Dissecting Host-Viral Interactons Through Focused or Unbiased High-Throughput Genetic Approaches, Daniel Poston
Student Theses and Dissertations

Replaying Life's Tape With Intraclonal Germinal Center Evolution, Tatsuya Araki
Student Theses and Dissertations

Mechanical Manipulation of Eukaryotic Chromatin by DNA-Binding Proteins, Tuan Nguyen
Student Theses and Dissertations

A Gain-of-Function Role of Apolipoprotein E2 in Melanoma Progression, Nneoma Adaku
Student Theses and Dissertations

Neural Control of Sickness Behavior, Anoj Ilanges
Student Theses and Dissertations

Anteromedial Thalamus Gates the Selection & Stabilization of Long-Term Memories, Andrew Toader
Student Theses and Dissertations

Rarely Acquired Type II-A CRISPR-Cas Spacers Mediate Anti-Viral Immunity Through the Targeting of a Non-Canonical PAM Sequence, Claire T. Kenney
Student Theses and Dissertations

Deep Molecular Characterization of Human Cortical Cell-Types, Christina Pressl
Student Theses and Dissertations

Transgenic Tools in Ants and the Representation of Alarm Pheromones in the Ant Antennial Lobe, Taylor Eco Hart
Student Theses and Dissertations

Structural and Functional Analysis of Substrate Recognition and Inhibition of the Multidrug Transporters MRP1 and MRP2, Harlan Linver Pietz
Student Theses and Dissertations

Cortical Control of Naturalistic Facial Expression Production in Primates, Geena Rose Ianni
Student Theses and Dissertations

Using Chemical Probes to Examine Cellular Activities, Megan Elizabeth Kelley
Student Theses and Dissertations

Antibody-Effector Functions in Antiviral Response, Kevin Shuolong Kao
Student Theses and Dissertations

Neotelomere Formation by Telomerase in Human Cells, Charles Gunnar Kinzig
Student Theses and Dissertations

Mechanistic Understanding of the Role of TRF1 in Telomere Replication, Zhe Yang
Student Theses and Dissertations

53BP1/Shieldin Counteract DSB Resection Through Fill-In Synthesis, Zachary Kenneth Mirman
Student Theses and Dissertations

Structure and Mechanism of PCAT1, a Polypeptide Processing and Secretion Transporter, Virapat Kieuvongngam
Student Theses and Dissertations

Uncovering Regulators of Whole-Body Metabolism by Chemoproteomic Profiling of the Adipocyte Secretome, Chan Hee J Choi
Student Theses and Dissertations

DNA Methylation and DNA Methyltransferases in the Clonal Raider Ant, Ooceraea biroi, Ivasyk Iryna
Student Theses and Dissertations

Ultra-Fast and Multi-Dimensional Face Processing in a New Face Area, Zetian Yang
Student Theses and Dissertations

Intestinal CD4+T Cell Responses to Food, Ainsley Lockhart
Student Theses and Dissertations

Songbird Brain Organization and its Molecular Convergence with Humans for Vocal Imitation Learning, Gregory Gedman
Student Theses and Dissertations

Ras Drives Malignancy Through Stem Cell Crosstalk with the Microenvironment, Shaopeng Yuan
Student Theses and Dissertations

Novel Optical Tools to Investigate Presenilin Control of Neurotransmission, Ryan J. Farrell
Student Theses and Dissertations

Integration Sites in the Persistence of Latent HIV-1, Amy S. Huang
Student Theses and Dissertations

The Effect of Early Dietary Intervention on Alzheimer's Disease-Related Pathology and Cognitive Function in Mice, Anna Amelianchik
Student Theses and Dissertations

New Roles for the Integrated Stress Response in Cancer and Proteostasis, Brian Hurwitz
Student Theses and Dissertations

Sensory and Neuromodulatory Entrainment of Foraging States in C. Elegans, Elias Scheer
Student Theses and Dissertations

Transcriptomic and Proteomic Studies of Intercellular Communication Between Melanocytes and Keratinocytes in Human Skin, Gabriella Stephanne Spitz-Becker
Student Theses and Dissertations

Reproductive Resilience of Aedes Aegypti Mosquitoes, Krithika Venkataraman
Student Theses and Dissertations

Structural Studies of the Nucleolar Stages of Ribosome Biogenesis in Yeast, Linamarie Miller
Student Theses and Dissertations

Multi-Modal Regualtion of Actin Networks, Lin Mei
Student Theses and Dissertations

Tumor Suppression by a TRNA Synthetase, Maria Passarelli
Student Theses and Dissertations

Non-Canonical Odor Coding Ensures Robust Mosquito Attraction to Humans, Margaret Herre
Student Theses and Dissertations

Modulation of Prefrontal Cortex activity and sociability by local interneurons expressing corticotropi-releasing hormone, Michael Riad
Student Theses and Dissertations

Biased Constitutive Activity in the Uveal Melanoma Oncogene CYSLTR2 is Unique in CYSLTR2 Germline and Pan-Cancer Human Variome, Mizuho Horioka-Duplix
Student Theses and Dissertations

Restriction-Modification and CRISPR-Cas Systems: Cooperation Between Innate and Adaptive Immunity in Prokaryotes, Pascal Maguin
Student Theses and Dissertations

B Cell Receptor Signalng in Germinal Centers, Spencer T. Chen
Student Theses and Dissertations

Characterization of a Novel Sensing Mechanism Governing Antigenic Variation in P. Falciparum, Victoria M. Schneider
Student Theses and Dissertations

Characterizing Inflammatory Mechanisms in Hidradenitis Suppurativa, Kristina Navrazhina
Student Theses and Dissertations

Pathogenic Characterization and Therapeutic Development for Fiblrolamellar Hepatocellular Carcinoma, Solomon N. Levin
Student Theses and Dissertations

Cerebral Amyloid Angiopathy-Causing Beta-Amyloid Variants Have Altered Effects on the Clotting System, Steven Cajamarca
Student Theses and Dissertations

Chemical Tools for Exploring Metabolite Interactions with Nuclear Receptors and Beyond, Taku Tsukidate
Student Theses and Dissertations

Noggin Transport in a Model Human Epiblast, Tiên Phan-Everson
Student Theses and Dissertations

A-to-I RNA Editing in Human Cells, Tony Sun
Student Theses and Dissertations

Quantifying the Release of Protein Substrates from AAA+ ATPase ClpX by Single Molecule Total Internal Reflection Fluorescence Microscopy, Xiao Wang
Student Theses and Dissertations

Deciphering Cancer Metabolic Dependencies in the Tumor Microenvironment, Xiphias Ge Zhu
Student Theses and Dissertations

The Identification of a Leptin Dependent Neural Pathway Regulating Adipose Tissue Innervation, Putianqi Wang
Student Theses and Dissertations

Linker Histone Medicated Regulation of Mitotic Chromosome Compaction and Individualization, Pavan Choppakatla
Student Theses and Dissertations

Single-Molecule Investigation of Chromatin-Associated Factors in Genome Organization and Epigenetic Maintenance, Rachel Leicher
Student Theses and Dissertations

Transcriptional Regulation of the Metabolic Response to Therapy in Leukemia, Robert Thomas Williams
Student Theses and Dissertations

The Role of Compartmentalized Metabolism in Cellular Metal Homeostasis, Ross A. Weber
Student Theses and Dissertations

A Translational Approach to Modeling Unique Aspects of Germ Cell Development During Self-Organization of the Primate Embryo, Rohan R. Soman
Student Theses and Dissertations

Finding Common Ground: The Common Marmoset as a Model to Accessing and Providing Insight into the Social Brain, Margaret Fabiszak
Student Theses and Dissertations

A Role for ACSBG1 in Obesity-Accelerated Breast, Olivia Maguire
Student Theses and Dissertations

Developmental Dynamics of 5-Hydroxymethylcytosine and its Role in the Terminal Differentiation of Neurons, Elitsa Stoyanova
Student Theses and Dissertations

Structural Study of Disease Relevant ABC Transporters-Cystic Fibrosis Transmembrane Conductance Regulator and ABCA4, Fangyu Liu
Student Theses and Dissertations

Unraveling the Interaction Between Beige Adipocytes and the Sympathetic Nervous System, Jingyi Chi
Student Theses and Dissertations

Interactions Between Microbial, Neuronal, and Immune Cells in the Digestive System, Fanny Matheis
Student Theses and Dissertations

Accessory Nucleases Provide Robust Antiparasite Immunity for Type III CRISPR-Cas Systems, Jakob Træland Rostøl
Student Theses and Dissertations

Brochemical Studies of Peptidoglycan Hydrolases from Commensal and Pathogenic Bacteria, Juliel Espinosa
Student Theses and Dissertations

Restriction of Food Intake by Dorsomedial Hypothalamus, Caner Caglar
Student Theses and Dissertations

A Proteomic Approach to Elucidating the Function of Picornavirus 2A Protease, Artem Serganov
Student Theses and Dissertations

The Role of DNA Methylation in Defining the Vocal Learning Transcriptome of the Zebra Finch, Caitlin Sun Gilbert
Student Theses and Dissertations

Genome-Wide Human-Specific RNA Regulatory Elements in the Brain, Elisabeth A. Murphy
Student Theses and Dissertations

Non-Canonical Axonal Insulin Receptor signaling Drives Aversive Olfactory Learning, Du Cheng
Student Theses and Dissertations

Mechanisms for the Evolution of Superorganismality in Ants, Vikram Chandra
Student Theses and Dissertations

Not Black and White: BMP Signaling Drives Melanocyte Differentiation Down Stream of Stem Cell Activation, Nicole Rai Infarinato
Student Theses and Dissertations

Metabolic Coordination of Stem Cell Fate Controls Tumor Initiation and Tissue Repair, Sanjeethan C. Baksh
Student Theses and Dissertations

Tension Propagation Along Tip-Link Cadherins: Regulation and Implications for the Auditory System, Daniel M. Firester
Student Theses and Dissertations

The Role of Nutrient Availability in Therapeutic Response of Leukemia, Rohiverth Guarecuco Jr
Student Theses and Dissertations

The Taste of Blood, Veronica Jove
Student Theses and Dissertations

The Role of Adipocytes in the Tumor Microenvironment in Obesity-Driven Breast Cancer Progression, Sarah Ackerman
Student Theses and Dissertations

A Network Approach to Understanding miRNA Regulation in Adipose Tissue, Sean O’Connor
Student Theses and Dissertations

A Role for Mindbomb 1 in Adenovirus Genome Delivery, Stephanie Sarbanes
Student Theses and Dissertations

CRISPR/CASTE: Functional Genomic Studies of the Major Evolutionary Innovations of Ants, Waring Trible
Student Theses and Dissertations

Identification of Gene Expression Changes in Sleep Mutants Associated With Reduced Longevity in Drosophila, Zikun Wang
Student Theses and Dissertations

Characterizing the RNA Editing Specificityof ADAR Isoforms and Deaminase Domains In Vitro, Mariel Therese Bartley
Student Theses and Dissertations

Small-Molecule Activation of YAP for Inner-Ear Regeneration and Beyond, Nathaniel Kastan
Student Theses and Dissertations

Molecular Mechanisms and Antigen Receptor Requirements for Lymphocyte Adaptation to Intestinal Tissues, Mariya B. London
Student Theses and Dissertations

Monogenic Defects of the Type I Interferons Signaling Pathway in Humans: Molecular and Clinical Implications, Nicholas Hernandez
Student Theses and Dissertations

Sympathy for the Microbiota: How Changes in Gut Microbial Composition Influence the Immune System and Basic Physiology by Way of the Sympathetic Nervous System, Paul Andrew Muller
Student Theses and Dissertations

Analyzing Resistance to Design Chemical Inhibitors of AAA Proteins, Rudolf Pisa
Student Theses and Dissertations

DDI1/2 and RTF2-Dependent Regulation of RNASE H2 at the Replisome Ensures Genome Stability, Brooke A. Conti
Student Theses and Dissertations

Genetic Functional Dissection of the Synaptic Output of a Dual-Function Integrating Neuron, Aylesse Sordillo
Student Theses and Dissertations

Representations of Reward and Movement in Drosophila Dopaminergic Neurons, Aryeh Zolin
Student Theses and Dissertations

Cryo-EM Studies of Bacterial RNA Polymerase, James Chen
Student Theses and Dissertations

Chemical Biology of Dynein, Cristina C. Santarossa
Student Theses and Dissertations

Molecular Characterization of Mammalian De Novo DNA Methyltransferase Chromatin Recruitment, Daniel N. Weinberg
Student Theses and Dissertations

Time-Restricted Feeding Extends Longevity in Drosophila Melanogaster, Daniel Cabrera
Student Theses and Dissertations

Visualizing Protease Activation, Retrochmp3 Activity, and VPR Recruitment During HIV-1 Assembly, Kate Bredbenner
Student Theses and Dissertations

Testing the T-loop Model of Telomeric End Protection, Leonid Alexeevich Timashev
Student Theses and Dissertations

Mechanisms of Evasion: Anti-Tumor Immune Suppression & TRNA-Dependent Growth in Cancer Metastasis, Lisa Brooke Noble
Student Theses and Dissertations

Dissection of Neurons and Circuits Involved in Regulating Innate Behaviors, Movement and Higher Cognitive Functions in Mice, Luca Parolari
Student Theses and Dissertations

Small Molecule Activation of Yap for Inner-Ear Regeneration and Beyond, Nathaniel Kastan
Student Theses and Dissertations

Cas9-Primed Adaptive Immunity During the CRISPR-Cas Response, Philip M. Nussenzweig
Student Theses and Dissertations

Identification of Previously Unknown Interactions Between G Protein-Coupled Receptors and Receptor Activity-Modifying Proteins, Emily Margaretha Lorenzen
Student Theses and Dissertations

Structural and Functional Studies of the Unconventional Proteobacterial Transcription Activator CRL in Complex with the Transcription Machinery, Alexis Jaramillo Cartagena
Student Theses and Dissertations

Hybridization in Ants, Ian Butler
Student Theses and Dissertations

Monogenic Defects of the Type 1 Interferon Signaling Pathway in Human: Molecular and Clinical Implications, Nicholas Hernandez
Student Theses and Dissertations

Cell Memory and Fate in Human Development, Anna Kresovich Yoney
Student Theses and Dissertations

Diverse Kappa Opioid Receptor Agonists: Relationships Between Signaling and Behavior, Amelia Dunn
Student Theses and Dissertations

Germline Genetic Determination of Cancer Outcome, Benjamin N. Ostendorf
Student Theses and Dissertations

Blood-Derived Plasminogen Modulates the Neuroimmune Response in Both Alzheimer's Disease and Systemic Infection Models, Sarah K. Baker
Student Theses and Dissertations

Spontaneity and Precision in the Drosophila Central Nervous System, Bennett Ferris
Student Theses and Dissertations

The Skin Remembers: Epigenetic Memories of Inflammation Past, Samantha B. Larsen
Student Theses and Dissertations

Regulation of Protein Degradation by ADP-Ribosylation, Yetis Gultekin
Student Theses and Dissertations

Who Said That? Towards a Machine-Prediction-Based Approach to Tursiops Truncatus Whistle Localization and Attribution in a Reverberant Dolphinarium, Sean Fisher Woodward
Student Theses and Dissertations

Generation of Memory of Infection During the CRISPR-Cas9 Immune Response, Robert Heler
Student Theses and Dissertations

From Face Perception to Individual Recognition: The Missing Link, Sofia Mariana Landi
Student Theses and Dissertations

Elucidation of the Functional Architecture of the Early Pre-Ribosomal Processing Machinery in Yeast, Mirjam Hunziker
Student Theses and Dissertations

Chemical Biology, Biochemical and Structural Studies of MDN1, an AAA Protein Required for Ribosome Biogenesis, Zhen Chen
Student Theses and Dissertations

Substrate Identification of an Oncogenic Kinase: Elucidating the Pathogenesis of a Rare Liver Cancer, Melissa Jarmel
Student Theses and Dissertations

Distinct Populations of Layer 5B Pyramidal Neurons in the Primary Motor Cortex, Maria V. Moya
Student Theses and Dissertations

Examining Mechanisms Regulating Microtubule Assembly and Function, Melissa Pamula
Student Theses and Dissertations

Multimodal Strategies of Host-Seeking Mosquitoes, Molly Zhen Liu
Student Theses and Dissertations

Sensory Coding and Olfactory Integration in Caenorhabditis Elegans, May Dobosiewicz
Student Theses and Dissertations

Oxytocin, Dopamine, and the Neuromodulation of Mating Behavior in C. Elegans, Meghan Aileen Lockard
Student Theses and Dissertations

Molecular Characterization of Novel Mutations in Fanconi Anemia Patients, Kimberly Rickman
Student Theses and Dissertations

GPCR Activation of the G Protein-Gated Inward-Rectifier Potassium Channel, Kouki Touhara
Student Theses and Dissertations

Molecular Mechanisms Underlying Stress-Induced GLIA Remodeling in the Nematode C. Elegans, In Hae Lee
Student Theses and Dissertations

Modeling Alzheimer's Disease Using CRISPR/CAS9 Gene Editing and Induced Pluripotent Stem Cells Reveals Conserved Cellular Mechanisms, Dylan Kwart
Student Theses and Dissertations

A Stress-Induced TRNA Depletion Response Mediates Codon-Based Translational Repression and Growth Suppression, Doowon Huh
Student Theses and Dissertations

Conformational Dynamics of the Nuclear Pore Complex Studied With Coarse-Grained Modelling and Polarized Light Microscopy, Joan Pulupa
Student Theses and Dissertations

The Role and Control of WNT Signalling in an HESC Model of Human Primitive Streak, Iain Martyn
Student Theses and Dissertations

Functional Organization of Molecular Memories in the CRISPR-Cas Immune System, Jon McGinn
Student Theses and Dissertations

The Role of ZMYND8 in Immunoglobulin Class Switch Recombination, Daniel Benjamin Rosen
Student Theses and Dissertations

On the Interactions of Augmin with Microtubules and the Mechanics of the Cross-Linker PRC1, Alejandro Dottore
Student Theses and Dissertations

Neural Mechanisms that Control an Innate Foraging Behavior in Caenorhabditis Elegans, Alejandro Lopez-Cruz
Student Theses and Dissertations

Dopamine and the Temporal Dependence of Learning and Memory, Annie Handler
Student Theses and Dissertations

Non-Coding RNA Features Critical to the Replication of HIV-1, Matthew A. Takata
Student Theses and Dissertations

In Vitro, In Vivo, and In Silico Studies of Reticulospinal Circuits and Generalized Arousal, Adele Bubnys
Student Theses and Dissertations

Center Manifold Dynamics in Randomly Coupled Oscillators and in Cochlea, Dimitrios Moirogiannis
Student Theses and Dissertations

A High-Throughput Approach to Uncover Novel Roles of APOBEC2, a Functional Orphan of the AID/APOBEC Family, Linda Molla
Student Theses and Dissertations

Multi-Modal Effects of the Repellent Deet Across Protostomia, Emily Jane Dennis
Student Theses and Dissertations

Chemical Approaches to Dynein Inhibition, Jonathan Baruch Steinman
Student Theses and Dissertations

Single Cell Analysis of the HIV-1 Latent Reservoir, Lillian Brumer Cohn
Student Theses and Dissertations

Surface Coat Replacement Dynamics and Antigen Glycosylation in T. Brucei Influence Evasion of the Host Antibody Response, Jason M. Pinger
Student Theses and Dissertations

Neural Circuit Mechanisms Underlying Behavioral Evolution in Drosophila, Laura Fairbanks Seeholzer
Student Theses and Dissertations

A Role for PI31-Mediated Proteasome Regulation in Proteostasis and Neuronal Health, Sandra Jones
Student Theses and Dissertations

Dopaminergic Modulation Shapes Sensorimotor Processing in the Drosophila Mushroom Body, Raphael Cohn
Student Theses and Dissertations

Making Ribosomes: Biochemical and Structural Studies of Early Ribosome Biogenesis in Yeast, Malik Chaker-Margot
Student Theses and Dissertations

In Search of Generic Properties of Evolved Systems: From Elasticity of Proteins to Structure of Metabolic Networks, Michael Robert Mitchell
Student Theses and Dissertations

IGDB-2, an IG/FNIII Protein, Binds the ION Channel LGC-34 and Controls Sensory Compartment Morphogenesis in C. Elegans, Wendy Wang
Student Theses and Dissertations

The Characterization of a Novel Complex Implicated in the Initiation of Apoptosis, Thomas Hsiao
Student Theses and Dissertations

The Role of Neuronal Pentraxin 1 in Promoting Pancreatic Cancer Progression, Yuehyi Gloria Wu
Student Theses and Dissertations

Daple Orients and Patterns Sensory Hair Bundles in the Inner Ear, Kimberly Siletti
Student Theses and Dissertations

Characterization and Reconstitution of S-Palmitoylated IFITM3 Antiviral Activity, Avital Percher
Student Theses and Dissertations

Netrin Guides Spinal Commissural Axons to the Midline at Long Range Through the Receptors DCC and Neogenin, Sze Sing Shaun Teo
Student Theses and Dissertations

Targeting the CD4 Binding Site of HIV, Lotta von Boehmer
Student Theses and Dissertations

Cell Type Specific Roles of Serotonin Receptor 4 in the Hippocampus and Neocortex in Emotion and Cognition, Remzi Karayol
Student Theses and Dissertations

Components Required for the Death and Degradation of the Linker Cell in C. Elegans, Lena Marlise Kutscher
Student Theses and Dissertations

Control of Salmonella Virulence by Microbiota-Derived and Dietary Fatty Acids, Zhenrun J. Zhang
Student Theses and Dissertations

Cell Cycle Control by Cyclin-CDKS in Chlamydomonas ReinhardtII, Kenneth C. Atkins
Student Theses and Dissertations

Robustness Enhancement of Sensory Transduction by Hair Bundles, Andrew Robert Milewski
Student Theses and Dissertations

Investigating Genetic (IN)Compatibility Between Temperate Phages and CRISPR-CAS Systems in Staphylococcus Aureus, Gregory W. Goldberg
Student Theses and Dissertations

Biological Consequences of Atypical Phage Conversion in Gram-Positive Pathogens, Douglas R. Deutsch
Student Theses and Dissertations

Modeling Alzheimer's Disease in Induced Pluripotent Stem Cells, Andrew Gregg
Student Theses and Dissertations

Identification and Characterization of Hells-CDCA7, a Nucleosome Remodeling Complex Required for Mitotic Chromosome Structure, Christopher Jenness
Student Theses and Dissertations

Characterizing Human Transfer RNAS by Hydro-TRNASEQ and PAR-CLIP, Tasos Gogakos
Student Theses and Dissertations

Compromising the 20S Proteasome Activates a Quality Control Pathway to Mitigate Proteotoxic Stress, Irit Shachrai
Student Theses and Dissertations

IR Laser-Induced Gene Expression for Tracking Development of Single Embryonic Neurons and Glia in C. Elegans, Anupriya Singhal
Student Theses and Dissertations

Separate Roles of FAN1 and Fanconi Anemia Proteins in DNA Interstrand Crosslink Repair and Human Disease, Supawat Thongthip
Student Theses and Dissertations

Apobec1-Mediated RNA Editing in Monocytes Contributes to Genetic Heterogeneity and Modulates Monocyte Activity and Development, Violeta Rayón Estrada
Student Theses and Dissertations

Deconvoluting Cell-Type Specific 3'UTR Isoform Expression in the Adult and Developing Cerebellum, Saša Jereb
Student Theses and Dissertations

High Throughput Detection of Pseudouridine: Caveats, Conundrums, and a Case for Open Science, Maryam Zaringhalam
Student Theses and Dissertations

Lysin Based Antimicrobial Peptides Against Acinetobacter Baumannii, Mya Thandar
Student Theses and Dissertations

Single Molecule Ligand Binding Studies on CCR5 by Fluorescence Cross-Correlation Spectroscopy, Carlos Rico
Student Theses and Dissertations

The Apoptotic and Wallerian Degeneration Pathways Regulate Disease Onset and Progression in the SOD-1G93A Transgenic Mouse Model of ALS, Deanna Belsky
Student Theses and Dissertations

A Comparative Study of Sensory Neuron Synaptic Activity and the Role of Presynaptic Diversity, Specificity, and Regulation in Caenorhabitis Elegans, Donovan Ventimiglia
Student Theses and Dissertations

Specification of Stem Cells and Niche During Hair Follicle Morphogenesis, Tamara Ouspenskaia
Student Theses and Dissertations

Structural and Functional Studies of Mycobacterial General Transcription Factors RbpA and CarD, Elizabeth Hubin
Student Theses and Dissertations

Home Sweet Home: Epigenetic Paths of Stem Cells In and Out of Their Niche, Rene C. Adam
Student Theses and Dissertations

Light Stimulation of Sensory Hair Cells, Julien Azimzadeh
Student Theses and Dissertations

Isopeptide and Ester Bond Ubiquitination Regulate Degradation of the Human Dopamine Receptor 4, Jennifer C. Peeler
Student Theses and Dissertations

Investigating Differentiation: A Role for Organelle Inheritance in Epidermal Growth, Amma Asare
Student Theses and Dissertations

A Neuronal Circuit Architecture for Angular Integration in Drosophila, Jonathan Green
Student Theses and Dissertations

Light Sheet Microscopy and Image Analysis of Neural Development and Programmed Cell Death in C. Elegans Embryos, Peter Insley
Student Theses and Dissertations

Regulated Recruitment of the Chromosomal Passenger Complex to Chromatin and Microtubules Promotes Accurate Cell Division, Michael Wheelock
Student Theses and Dissertations

The Physics of Rodent Ultrasonic Vocalizations, Matthew Dornfeld
Student Theses and Dissertations

Pathways of NHEJ at Dysfunctional Telomeres and Their Resolution, Roos Anna Karssemeijer
Student Theses and Dissertations

Transcriptional Governance of Hair Follicle Stem Cell Quiescence and Niche Maintenance in Long-Term Tissue Regeneration, Kenneth Lay
Student Theses and Dissertations

Density-Dependent Foraging in Caenorhabditis Elegans, Joshua Greene
Student Theses and Dissertations

Ralph M. Steinman: Research and Career, Carol L. Moberg, Judy Adams, Steinman Laboratory
Steinman and the Nobel Prize

Retrograde Activation of a Somatic Transcriptional Program Regulates Distal Axon Degeneration, Jason Pitts
Student Theses and Dissertations

Tracking the In Vivo Dynamics of Antigenic Variation in the African Trypanosome, Monica R. Mugnier
Student Theses and Dissertations

Characterization of Mechanisms That Mediate Cancer Metastatic Colonization, Alexander Huan Nguyen
Student Theses and Dissertations

Structural and Functional Characterization of SPOA Domains in Salmonella Typhimurium Type III Secretion Systems, Ryan Q. Notti
Student Theses and Dissertations

Genetic Dissection of Neural Circuits Underlying Value Based Decision Making, Hirofumi Nakayama
Student Theses and Dissertations

Reconstitution and Mechanistic Studies on the Staphylococcal agr Quorum Sensing Circuit, Boyuan Wang
Student Theses and Dissertations

Regulation of the Anaphase-Promoting Complex Examined at the Single Cell Level, Andrej Ondracka
Student Theses and Dissertations

Regulatory Architecture of Non-Apoptotic Cell Death Program in C. Elegans, Maxime Jeremie Kinet
Student Theses and Dissertations

CPISPR-CAS: From a Prokaryotic Immune System to a Gene Editing Tool, Wenyan Jiang
Student Theses and Dissertations

Extracellular Metabolic Energetics Can Promote Cancer Progression, Jia Min Loo
Student Theses and Dissertations

Aversive Olfactory Imprinting in Caenorhabditis Elegans, Xin Jin
Student Theses and Dissertations

Protein Regulators of Phosphoinositides as Promoters of Cancer Metastasis, Caitlin Anne Sengelaub
Student Theses and Dissertations

Selection Dynamics in the Germinal Center During Antibody Affinity Maturation, Alexander Gitlin
Student Theses and Dissertations

Analysis of Hepatocyte Secretion Pathways: A Case Study on Hepatic Apolipoproteins, Serum Albumin, and Hepatitis C Virus, Constantin N. Takacs
Student Theses and Dissertations

Characterization of Skin Immune Reactions Induced by the Contact Sensitizer Diphencyprone in Healthy Volunteers and Metastatic Melanoma Patients, Nicholas Gulati
Student Theses and Dissertations

Chemical Tools for Exploring IFITM3 S-Palmitoylation and Mechanism, Xiaoqiu Yuan
Student Theses and Dissertations

A Census of Human RNA-Binding Proteins, Stefanie Gerstberger
Student Theses and Dissertations

Plasticity of the Nuclear Pore Complex Revealed With Proteomics, Zhanna Hakhverdyan
Student Theses and Dissertations

Dynamics of HIV-1 Infection and Therapy In Vivo, Joshua Abraham Horwitz
Student Theses and Dissertations

Paleovirological Analyses of Endogenous Retroviruses and Host Innate Immune Effectors, Daniel Blanco Melo
Student Theses and Dissertations

Metabolic Regulation of Gene Expression through Differential Histone Acylation: The Regulation and Function of Histone Crotonylation, Benjamin R. Sabari
Student Theses and Dissertations

Investigating the Role of Muscleblind-Like 1 in the Suppression of Breast Cancer Progression, Lisa Fish
Student Theses and Dissertations

Qualitative and Quantitative Regulation of the Leptin Gene in vivo, Yi-Hsueh Lu
Student Theses and Dissertations

Molecular Basis of Mechanosensitivity, Josefina Ines del Marmol
Student Theses and Dissertations

Natural Products From Functional Screening of Soil Metagenomic Libraries, Hala Iqbal
Student Theses and Dissertations

Nanobody-Based Interactomic Studies of Single Transcripts During mRNA Maturation, Peter C. Fridy
Student Theses and Dissertations

Studies Towards the Discovery of Novel Natural Products Through Functional Analysis of Environmental DNA-Encoded Type II Polyketide Synthases, Debjani Chakraborty
Student Theses and Dissertations

Escherichia Coli as a New Platform for the Study of Phosphoinositides, Sergio Botero
Student Theses and Dissertations

The Genetics Of Mosquito Heat-Seeking Behavior, Román A. Corfas
Student Theses and Dissertations

A Reductionist Approach to Modeling Human Corticogenesis, Mohammad Zeeshan Ozair
Student Theses and Dissertations

Development of Novel Chemical Biology Tools for Probing Structure-Function Relationships in G Protein-Coupled Receptors, Tian He
Student Theses and Dissertations

Neural Circuit Dependence of Acute and Subacute Nociception in C. Elegans, Yifan Xu
Student Theses and Dissertations

Therapeutic Uses of Broadly Neutralizing Anti-HIV-1 Antibodies in Humanized Mice, Ariel Halper-Stromberg
Student Theses and Dissertations

Specialized Signals for Spatial Attention in the Ventral and Dorsal Visual Streams, Pablo Polosecki
Student Theses and Dissertations

Functional Dissection of Brainstem Circuitry, Alexander Ryan Nectow
Student Theses and Dissertations

Mechanical Control of Sensory Hair-Bundle Function, Joshua D. Salvi
Student Theses and Dissertations

A Genomic Portrait of Hepatitis C Virus and MicroRNA-122, Joseph M. Luna
Student Theses and Dissertations

A New Role for Beta-Amyloid in Alzheimer's Disease: Initiation of Thrombotic and Inflammatory Processes Via Coagulation Factor XII and Fibrinogen, Daria Zamolodchikov
Student Theses and Dissertations

Characterization of Bacterial Metabolites Involved in Host Pathogen Resistance, Kavita J. Rangan
Student Theses and Dissertations

Molecular Determinants of Tumor Re-Initiation in Breast Cancer, Jason Barzel Ross
Student Theses and Dissertations

A Reductionist Approach to Modeling Human Corticogenesis, Mohammad Zeeshan Ozair
Student Theses and Dissertations

Activity Based Profiling: New Insights into Metabolic Homeostasis, Keith Tan
Student Theses and Dissertations

The Effect of Chronic Hypertension on Neuropathology in the TGSWDI Mouse Model of Alzheimer's Disease, Anna Kruyer
Student Theses and Dissertations

Identification of TMEM2 as a SOX4 Transcriptional Target Involved in Breast Cancer Metastasis, Hyeseung Lee
Student Theses and Dissertations

Components of the Ubiquitin Proteasome System are Required for the Nonapoptotic Death of the C. Elegans Linker Cell, Jennifer Zuckerman Malin
Student Theses and Dissertations

Normalization Among Heterogeneous Population Confers Stimulus Discriminability on the Macaque Face Patch Neurons, Akinori F. Ebihara
Student Theses and Dissertations

Studies on the Maturation of Secreted Quorum Sensing Peptides That Regulates S. Aureus Virulence, Jeffrey Grant Johnson
Student Theses and Dissertations

Effects of Temporal and Spatial Context Within the Macaque Face-Processing System, Clark Andrew Fisher
Student Theses and Dissertations

Why Mosquitoes Bite Some People More Than Others: Metabolic Correlates of Human Attraction in AEDES AEGYPTI, Lindsay Lee Bellani
Student Theses and Dissertations

Metagenomics-Based Tryptophan Dimer Natural Product Discovery and Development Pipeline, Fang-Yuan Chang
Student Theses and Dissertations

Synapse Formation in the Zebrafish Lateral Line, Eliot Dow
Student Theses and Dissertations

Mechanism of Action of ING4 as a Transcriptional Coactivator of p53, Jabez Bok
Student Theses and Dissertations

Xenopus DPPA2 is a Direct Inhibitor of Microtubule Polymerization Required for Nuclear Assembly, John Zhao Xue
Student Theses and Dissertations

Mechanisms of Olfactory Plasticity in Caenorhabditis Elegans, Christine Cho
Student Theses and Dissertations

Hair Bundles of a Jawless Vertebrate Employ Tetrapod-Like Tuned Mechanical Amplification, Katherine J. Leitch
Student Theses and Dissertations

A Mechanism for Spatial Orientation Based on Sensory Adaptation in Caenorhabditis Elegans, Johannes Larsch
Student Theses and Dissertations

Investigating Mechanisms of Telomere End-Protection, Shaheen Kabir
Student Theses and Dissertations

CalciumSignalExtract: A Matlab GUI to Automatically Extract the Activity of Multiple Cells from Calcium Imaging Data, Stephan Meyer Zum Alten Borgloh
Gilbert Laboratory

Forces Generated by Cell Intercalculation Tow Epidermal Sheets in Mammalian Tissue Morphogenesis, Evan Heller
Student Theses and Dissertations

Identification of a Microrna Network that Regulates Melanoma Metastasis and Angiogenesis by Targeting Apoe, Nora Pencheva
Student Theses and Dissertations

Causes and Consequences of Genetic Robustness and Fragility in HIV-1 Proteins, Suzannah J. Rihn
Student Theses and Dissertations

Transcriptome-Wide Characterization of APOBEC1-Catalyzed RNA Editing Events in Macrophages, Claire Ellen Hamilton
Student Theses and Dissertations

Split Inteins: From Mechanistic Studies to Novel Protein Engineering Technologies, Neel H. Shah
Student Theses and Dissertations

Stochastic Activation of Enhancers in the Innate Immune Response by the Histone Demethylase JMJD2D, Rohit Chandwani
Student Theses and Dissertations

RNA Deregulation in Metastatic Breast Cancer, Christina Beate Marney
Student Theses and Dissertations

Mutations in a Mechanosensitive Channel Enable Intravascular Metaststic Cell Survival, Paul William Furlow
Student Theses and Dissertations

HIV Specific B Cell Response in Patients With Broadly Neutralizing Serum Activity, Johannes F. Scheid
Student Theses and Dissertations

Exploration of Cell Cycle-Specific Essential Gene Functions in the Microbial Plant Chlamydomonas Reinhardtii, Frej Tulin
Student Theses and Dissertations

The Neuropeptide Regulation of Host-Seeking Behavior in Aedes Aegypti Mosquitoes, Jeff Liesch
Student Theses and Dissertations

Mechanism and Evolutionary Origins of HIV-1 Virion Entrapment by Tetherin, Siddarth Venkatesh
Student Theses and Dissertations

Coordinating Stem Cell Behavior in the Hair Follicle, Chiung-Ying Chang
Student Theses and Dissertations

Taming a Potent Mutator: Identification and Characterization of Novel Mechanisms of Regulating Antibody Diversification in B-Lymphocytes, Rebecca Kyle Delker
Student Theses and Dissertations

Abdominal-B Neurons Control Drosophila Virgin Female Receptivity, Jennifer J. Bussell
Student Theses and Dissertations

High Resolution Maps of the Vasculature of An Entire Organ, Oppenheim N. Jacob
Student Theses and Dissertations

Genome-Wide Characterization of the Effects of Nucleic Acid Modifying Enzymes: Cytidine Deaminases and DNA Methylation, Eric Luke Fritz
Student Theses and Dissertations

The Structural and Biochemical Characterization of Salmonella Host Specificity Determinant Gifsy-2 Gene E, Amanda C. Kohler
Student Theses and Dissertations

Identification of a Functional Hotspot on Ubiquitin Required for Stimulation of Methyltransferase Activity on Chromatin, Matthew Thomas Holt
Student Theses and Dissertations

Studies of a Novel Phage Lytic Enzyme, PlySs2, Daniel B. Gilmer
Student Theses and Dissertations

Chromatin Control of the Antiviral Response to Influenza, Jessica Sook Yuin Ho
Student Theses and Dissertations

The Origin of Multiple Sclerosis Revisited: The Case for a Soluble Toxin, Kareem Rashid Rumah
Student Theses and Dissertations

Functional and Structural Studies of the Human Voltage-Gated Proton Channel, James Anthony Letts
Student Theses and Dissertations

Estimating the Amount of Information Conveyed by a Population of Neurons, Marshall Crumiller
Knight Laboratory

Mechanism of Translational Control by the Fragile X Mental Retardation Protein and Creation of the FMRP CTAG Mouse, Sarah Van Driesche
Student Theses and Dissertations

Telomere-Driven Tetraploidy and its Relevance to Cancer, Teresa Davoli
Student Theses and Dissertations

Analysis of Small Molecule Inhibitors Aimed at Bacterial Virulence, Paul Daniel Dossa
Student Theses and Dissertations

Decoding 5HMC as an Active Chromatin Mark in the Brain and its Link to Rett Syndrome, Pinar Ayata
Student Theses and Dissertations

Frequency Selectivity of Synaptic Exocytosis in Hair Cells of the Bullfrog's Amphibian Papilla, Suchit H. Patel
Student Theses and Dissertations

An Analysis of Synaptotagmins in Caenorhabditis Elegans, Laura Winzenread
Student Theses and Dissertations

Examining the Regulation of Cell Division by the Spindle Assembly Checkpoint, Maria Maldonado
Student Theses and Dissertations

Cannabinoid CB1R Receptor Mediates Metabolic Syndrome in Models of Circadian and Glucocorticoid Dysregulation, Nicole Bowles
Student Theses and Dissertations

RNA Dynamics in T Cell Activation, Emily Conn Gantman
Student Theses and Dissertations

Top-Down Control of Lateral Interactions in Visual Cortex, Nirmala Ramalingam
Student Theses and Dissertations

Deep Brain Stimulation to Increase Generalized Arousal in Intact Mice and a Mouse Model of Traumatic Brain Injury, Amy Wells Quinkert
Student Theses and Dissertations

Studies of G Protein-Coupled Receptor Stability and Dimerization Using Novel Fluorescence and Crosslinking Approaches, Adam Knepp
Student Theses and Dissertations

Application of Genetically-Encoded Photoactivatable Crosslinkers to Map Ligand-Binding Sites on G Protein-Coupled Receptors, Amy Grunbeck
Student Theses and Dissertations

Phenotypic and Genotypic Models of Streptococcal Colonization of the Human Tonsil, Dennis J. Spencer
Student Theses and Dissertations

Tuning of Neuronal Excitation by a Brain Specific Microrna MIR-128: From Targets to Behavior, Chan Lek Tan
Student Theses and Dissertations

Discovery and Characterization of Methylation of Arginine 42 on Histone H3: A Novel Histone Modification with Positive Transcriptional Effects, Fabio Casadio
Student Theses and Dissertations

Novel Molecules from Environmental DNA-Derived Type II Polyketide Biosynthetic Gene Clusters, Ryan W. King
Student Theses and Dissertations

The Measurement of Information Transmitted by a Neural Population: Promises and Challenges, Marshall Crumiller, Bruce Knight, Ehud Kaplan
Knight Laboratory

Meyer Navigator: User ScanImage Functions to Show x/y Positions of the Stage/Objective in a Coordinate System, Stephan Meyer Zum Alten Borgloh
Gilbert Laboratory

From Single-SNP to Wide-Locus: Genome-Wide Association Studies Identifying Functionally Related Genes and Intragenic Regions in Small Sample Studies, Knut M. Wittkowski, Vikas Sonakya, Tingting Song, Martin P. Seybold, Mehdi Keddache, Martina Durner
Krueger Laboratory

Chemical Reporters for Investigating Lipidated Proteins at the Host-Pathogen Interface, Guillaume Charron
Student Theses and Dissertations

Mechanisms That Ensure the Proper Terminal Structure of Mammalian Telomeres, Peng Wu
Student Theses and Dissertations

Genetic Variation in Neurotransmitter Receptors Generates Behavioral Diversity, Andres Bendesky
Student Theses and Dissertations

Efforts Toward Production of Novel Natural Products From Uncultured Soil Microbes, Jacob Joseph Banik
Student Theses and Dissertations

The Extent and Nature Of Chromosomal Rearrangements in B Lymphocytes, Isaac Andrew Klein
Student Theses and Dissertations

Dissecting Mammalian Replication-Independent Chromatin Assembly – Biochemical and Structural Studies on the H3.3-Specific Histone Chaperones Hira and Daxx, Simon Elsässer
Student Theses and Dissertations

Glia Delimit Shape Changes Of Sensory Neuron Receptive Endings in C. elegans, Carl Procko
Student Theses and Dissertations