A reaction vessel and manual shaker; accession no. 39
The first apparatus for solid phase peptide synthesis was made by Bruce Merrifield in the basement of his home. It was adapted from an old greasy-looking piece of equipment that Moses Kunitz used many years earlier for dialysis. Later, Bruce Merrifield took one of Lyman Craig's rotary evaporators, cut it apart, turned it inside out, and made a shaker our of that.
The photograph shows the apparatus that the instrument shop of the Rockefeller University built for Dr. Merrifield in 1963.
Photo by Lubosh Stepanek
Bruce Merrifield, manual shaker, peptide synthesizer