Student Theses and Dissertations

 

The Rockefeller University has awarded over one thousand Ph.D’s since 1959. This collection contains theses beginning with the graduating class of 2006. Earlier theses are added by request or as permission to digitize is received. For more information visit the FAQ page.

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2013

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Application of Genetically-Encoded Photoactivatable Crosslinkers to Map Ligand-Binding Sites on G Protein-Coupled Receptors, Amy Grunbeck

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Novel Molecules from Environmental DNA-Derived Type II Polyketide Biosynthetic Gene Clusters, Ryan W. King

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Studies of G Protein-Coupled Receptor Stability and Dimerization Using Novel Fluorescence and Crosslinking Approaches, Adam Knepp

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Examining the Regulation of Cell Division by the Spindle Assembly Checkpoint, Maria Maldonado

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Frequency Selectivity of Synaptic Exocytosis in Hair Cells of the Bullfrog's Amphibian Papilla, Suchit H. Patel

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Deep Brain Stimulation to Increase Generalized Arousal in Intact Mice and a Mouse Model of Traumatic Brain Injury, Amy Wells Quinkert

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Top-Down Control of Lateral Interactions in Visual Cortex, Nirmala Ramalingam

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Phenotypic and Genotypic Models of Streptococcal Colonization of the Human Tonsil, Dennis J. Spencer

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Tuning of Neuronal Excitation by a Brain Specific Microrna MIR-128: From Targets to Behavior, Chan Lek Tan

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An Analysis of Synaptotagmins in Caenorhabditis Elegans, Laura Winzenread

2012

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Exploring Synaptic Vesicle Exocytosis, Pablo Ariel

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Dissecting Synaptic Vesicle Endocytosis, Moritz Armbruster

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Structure and Organization of Nuclear Pore Proteins, Claire Atkinson

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PHDS, Stress, And Starvation: The Identification Of A New RPD3 Deacetylase Complex Involved In The Yeast Oxidative Stress And Metabolism Pathways, Lindsey A. Baker

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Efforts Toward Production of Novel Natural Products From Uncultured Soil Microbes, Jacob Joseph Banik

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Induction of Innate and Adaptive Immunity In Vivo by Selective Antibody Targeting of Poly dA:dT and Antigen to Dendritic Cells, Scott A. Barbuto

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Vocal Handedness: The Emergence of Lateralization at Fledging, Rudy Bellani

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Genetic Variation in Neurotransmitter Receptors Generates Behavioral Diversity, Andres Bendesky

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Chemical Reporters for Investigating Lipidated Proteins at the Host-Pathogen Interface, Guillaume Charron

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The Application of Functional Metagenomics to Natural Products Research, Jeffrey William Craig

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Characterization of the Central Cavity of a Potassium Channel: Helix Dipoles, Conformational Plasticity and Inhibition, Disan Schold Davis

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Dissecting Mammalian Replication-Independent Chromatin Assembly – Biochemical and Structural Studies on the H3.3-Specific Histone Chaperones Hira and Daxx, Simon Elsässer

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Chemical Reporters for Bacterial Pathogenesis and Beyond, Markus Grammel

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The Neural Circuit for Behavioral Responses to Pheromone and Social Behavior in Caenorhabditis Elegans, Heeun Jang

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Analysis of Behavior in Populations of Swimming Microbes, David Jordan

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Identification of a Novel Regulator of ER Stress-Induced Apoptosis, Genevieve S. Joseph

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The Dynamic Streptococcus Pyogenes Transcriptome in the Host Cell Environment and Contributions by Phage, Barbara Juncosa

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WIP1 Phage Specificity for B. Anthracis, Sherry Kan

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The Extent and Nature Of Chromosomal Rearrangements in B Lymphocytes, Isaac Andrew Klein

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Structural and Functional Studies of SLO K+ Channels: Mechanisms of Gating by Intracellular Signaling, Manuel D. Leonetti

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Roles of the Methylcitrate and Methylmalonyl-COA Pathways in Mycobacterial Metabolism and Pathogenesis, Manisha Ulhas Lotlikar

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The GluK4 Kainate Receptor Subunit Regulates Mood, Memory and Excitotoxic Neurodegeneration, Emily Rhodes Lowry

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Conserved and Novel Properties of Clathrin-Mediated Endocytosis in Dictyostelium Discoideum, Laura Macro

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Structure Function Analysis of Adenosine Deaminase Acting on tRNA (ADAT2) from Trypanosoma Brucei, Miller Marshall

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The Expression of the Zinc Finger Transcription Factor zDC Defines the Classical Dendritic Cell Lineage, Matthew M. Meredith

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The Diversity of Cortical Interneurons, Miho Nakajima

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Progress Towards Integrated Models of HCV Dynamics, Thomas S. Oh

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rRNA Promoters as Targets for Transcription Factors: Structural and Functional Studies of PhERI and CarD, Joseph S. Osmundson

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Micrornas in Breast Cancer Metastasis: Molecular Regulation of Endothelial Recruitment by Cancer Cells & Regulation of Metastasis Suppressor Micrornas, Kim J. Png

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Glia Delimit Shape Changes Of Sensory Neuron Receptive Endings in C. elegans, Carl Procko

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Protein Phosphatase 1 at the Kinetochore Regulates Chromosome Segregation, Jessica Scott Rosenberg

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Molecular and Functional Characterization of Pyramidal Cell Types in the Frontal Cortex of Mouse Brain, Prerana Shrestha

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Sample Path Analysis of Integrate-and-Fire Neurons, Thibaud Taillefumier

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Examining Intracellular Phosphorylation Gradients During Cell Division, Lei Tan

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Approaches to Study Small Molecule Inhibitors and Their Targets, Sarah Anne Wacker

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Variability in Singing and in Song in the Zebra Finch, Cameron Wellock

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Using "Designer" Nucleosomes to Study Enzymatic Crosstalk Between Histone Ubiquitylation and Histone Methyltransferases, Sarah J. Whitcomb

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Mechanisms That Ensure the Proper Terminal Structure of Mammalian Telomeres, Peng Wu

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Develoment and Application of Chemical Strategies to Study Protein Fatty-Acylation in Eukaryotes, Mingzi Zhang

2011

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Defining Gene Expression in Normal Human Epidermal Keratinocytes and Melanocytes: A Prerequisite for Understanding Hyperplastic and Neoplastic Pathology, Erika de Wyllie Billick

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The Role of 53BP1 in DNA Double-Strand Break Repair, Anne Helen Bothmer

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DRE-1/FBXO11, A Conserved F Box Protein, Regulates Apoptosis in C. elegans and is Mutated in Human Lymphoma, Michael Chiorazzi

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Assessing the Phylogenetic and Cultural Content of Learned Song, Nicole Creanza

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From Microarrays to Behavior: Genes Controlled by Feeding State in Mosquitoes and Flies, Shelli F. Farhadian

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Cell-Type Specific Translational Profiling in Huntington's Disease Mouse Models, Robert J. Fenster

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Long-Term Quantitative Microscopy: From Microbial Population Dynamics to Growth of Plant Roots, Zak Frentz

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Antigen presentation : Influence of Cell Type and Route of Antigen Uptake, Alice O. Kamphorst

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Spatial Control of CDC42 Activation Regulates Cell Width and Growth Zone Formation, Felice D. Kelly

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Natural Product Biosynthesis In Uncultured Bacteria, Jeffrey Kim

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The Role of the Stereociliary Glycocalyx in Hair Bundle Cohesion, Adria Claire Le Boeuf

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Rapid Functional Dissection of Genetic Networks Via RNAi In Mouse Embryos, Geulah Livshits

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Regulation of Polarized Protein Transport to Axons, Dendrites, and Sensory Cilia in Caeborhabditis Elegans Neurons, Tapan Apurva Maniar

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Studies of the Kinetics of Cell Cycle Processes in S. Cerevisiae: The Molecular Basis of Start Irreversibility and Cyclin-Cdk Ordering of Mitotic Events, Catherine Oikonomou

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Sensory Organ Morphogenesis in Caenorhabditis Elegans, Grigorios Oikonomou

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The Long-Rage Directional Behavior of the Nematode C. Elegans, Margherita Peliti

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Structure-Function Analysis of Insect Olfactory Receptors, Maurizio Pellegrino

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Mitotic Exit: Thresholds and Targets, Andrea Geoghegan Procko

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Expanding the Horizons of Enzybiotic Identification, Jonathan Edward Schmitz

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A Hydrodynamic Sensory Antenna Used By Killifish for Nocturnal Hunting, Jason S. Schwarz

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A Proteomic and Genomic Investigation Into Replication Fork Dynamics in Saccharomyces Cerevisiae, Matthew David Sekedat

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Net Addition and Long-Term Survival of Adult-Born Neurons in the Zebra Finch HVC: Why Replace When You Can Keep Them All?, Clare Walton

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Bioorthogonal Chemical Reporters Reveal Fatty-Acylation of Histone H3 Variants and Cholesterol Modification of Proteins and Trafficking in Cells, John P. Wilson

2010

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Mechanisms of Controlled Proteolysis during Drosophila Spermatogenesis: Coordinate Action of Apoptotic Caspases and the Ubiquitin-Proteasome System, Maya Bader

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Exosporium Morphogenesis in Bacillus Cereus and Bacillus Anthracis, Monica Maria Fazzini Bellinzona

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A Molecular Mechanism for Endocytic Recycling of the M5 Muscarinic Acetylcholine Receptor, Jacob T. Bendor

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Structural and Functional Characterization of B. Anthracis Udp-Glcnac 2-Epimerase and Salmonella Secreted Effector I, Shyam Bhaskaran

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Variability and Dynamics of Apoptotic Events in Single Cells, Patrick Bhola

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Structural Studies on the Regulation of Sporulation in Bacillus and Antibiotic Sulfation, Matthew J. Bick

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Genome-Wide Decoding of mRNP and miRNA Maps, Sung Wook Chi

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The Role of Lysogenic Bacteriophage in Virulence and Survival of Streptococcus Pyogenes, Chad W. Euler

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Visualizing Synaptic Specificity with GRASP, Evan H. Feinberg

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Cell Death Mechanisms in Drosophila Differentiated Photoreceptor Neurons, Alexis Robert Gambis

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Characterization of Histone H2A Functional Domains Important for Regulation of the DNA Damage Response, Elizabeta Gjoneska

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Genome-Wide Localization And Novel Deposition Pathways Of Histone Variant H3.3 In Embryonic Stem And Neuronal Precursor Cells, Aaron David Goldberg

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Unzipping Amyloid Fibrils: How a Novel Calcium-Binding Protein, NUCB1, Prevents the Formation of Amyloid Fibrils, Neeraj Kapoor

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Genome-Scale Genetics: Lessons from Founder Populations, Eimear Elizabeth Kenny

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Controls Over S-Phase And Over Nuclear Synchrony, Lee Maxine Kiang

Cellular Signaling in Development of the Cochlear Tonotopic Gradient, Lukasz Kowalik

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Reconstitution and Characterization of Human Endogenous Retrovirus-K, Young Nam Lee

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Mechanisms for Maintaining Cell Identity in C.elegans Olfactory Neurons, Bluma J. Lesch

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Mitotic Exit Control in Budding Yeast: Regulators and Dynamics, Ying Lu

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Mechanistic Insights into the Stimulation of Dot1L-Mediated Methylation of Histone H3 by Semisynthetically Ubiquitylated Histone H2b, Robert Kendall McGinty

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Dynamic and Integrative Properties of the Primary Visual Cortex, Justin N. J. McManus

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Structural and Molecular Correlates of Individual Differences in Anxiety Behavior and the Stress Response, Melinda Miller

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Dissecting the Contribution of the Carboxyl-Terminal Domain and Tail of HIV-1 Integrase to Viral Dynamics and Enzymatic Function, Kevin Dominic Mohammed

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Synaptic Specificity in the Zebrafish Lateral Line, Aaron Nagiel

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Biochemical and Structural Analysis of the Nucleoporin Nup214 and its Involvement in mRNA Export, Johanna Napetschnig

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Localization and Function Of RNA Interference in the Cerebral Cortex, John T. G. Pena

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Regulation of Surface Proteins Assembly on the Wall of Gram-Positive Bacteria, Assaf Raz

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Characterization of the Functional Role of the Intracellular Cholesterol Transporter StARD4 in Knockout Mice, and Investigation of Epigenetic Modulation of ApoA-I Transcription, Joshua Riegelhaupt