Student Theses and Dissertations

 

The Rockefeller University has awarded over one thousand Ph.D’s since 1959. This collection contains theses beginning with the graduating class of 2006. Earlier theses are added by request or as permission to digitize is received. For more information visit the FAQ page.

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2017

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Home Sweet Home: Epigenetic Paths of Stem Cells In and Out of Their Niche, Rene C. Adam

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Investigating Differentiation: A Role for Organelle Inheritance in Epidermal Growth, Amma Asare

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Light Stimulation of Sensory Hair Cells, Julien Azimzadeh

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The Apoptotic and Wallerian Degeneration Pathways Regulate Disease Onset and Progression in the SOD-1G93A Transgenic Mouse Model of ALS, Deanna Belsky

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The Physics of Rodent Ultrasonic Vocalizations, Matthew Dornfeld

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Apobec1-Mediated RNA Editing in Monocytes Contributes to Genetic Heterogeneity and Modulates Monocyte Activity and Development, Violeta Rayón Estrada

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Density-Dependent Foraging in Caenorhabditis Elegans, Joshua Greene

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A Neuronal Circuit Architecture for Angular Integration in Drosophila, Jonathan Green

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Structural and Functional Studies of Mycobacterial General Transcription Factors RbpA and CarD, Elizabeth Hubin

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Light Sheet Microscopy and Image Analysis of Neural Development and Programmed Cell Death in C. Elegans Embryos, Peter Insley

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Deconvoluting Cell-Type Specific 3'UTR Isoform Expression in the Adult and Developing Cerebellum, Saša Jereb

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Pathways of NHEJ at Dysfunctional Telomeres and Their Resolution, Roos Anna Karssemeijer

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Transcriptional Governance of Hair Follicle Stem Cell Quiescence and Niche Maintenance in Long-Term Tissue Regeneration, Kenneth Lay

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Specification of Stem Cells and Niche During Hair Follicle Morphogenesis, Tamara Ouspenskaia

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Isopeptide and Ester Bond Ubiquitination Regulate Degradation of the Human Dopamine Receptor 4, Jennifer C. Peeler

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Single Molecule Ligand Binding Studies on CCR5 by Fluorescence Cross-Correlation Spectroscopy, Carlos Rico

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Compromising the 20S Proteasome Activates a Quality Control Pathway to Mitigate Proteotoxic Stress, Irit Shachrai

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IR Laser-Induced Gene Expression for Tracking Development of Single Embryonic Neurons and Glia in C. Elegans, Anupriya Singhal

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Lysin Based Antimicrobial Peptides Against Acinetobacter Baumannii, Mya Thandar

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Separate Roles of FAN1 and Fanconi Anemia Proteins in DNA Interstrand Crosslink Repair and Human Disease, Supawat Thongthip

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A Comparative Study of Sensory Neuron Synaptic Activity and the Role of Presynaptic Diversity, Specificity, and Regulation in Caenorhabitis Elegans, Donovan Ventimiglia

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Regulated Recruitment of the Chromosomal Passenger Complex to Chromatin and Microtubules Promotes Accurate Cell Division, Michael Wheelock

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High Throughput Detection of Pseudouridine: Caveats, Conundrums, and a Case for Open Science, Maryam Zaringhalam

2016

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Melanocyte - Keratinocyte Interactions and Intercellular Communication in the Skin, Rachel L. Belote

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Escherichia Coli as a New Platform for the Study of Phosphoinositides, Sergio Botero

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Studies Towards the Discovery of Novel Natural Products Through Functional Analysis of Environmental DNA-Encoded Type II Polyketide Synthases, Debjani Chakraborty

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The Genetics Of Mosquito Heat-Seeking Behavior, Román A. Corfas

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Nanobody-Based Interactomic Studies of Single Transcripts During mRNA Maturation, Peter C. Fridy

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A Census of Human RNA-Binding Proteins, Stefanie Gerstberger

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Selection Dynamics in the Germinal Center During Antibody Affinity Maturation, Alexander Gitlin

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Characterization of Skin Immune Reactions Induced by the Contact Sensitizer Diphencyprone in Healthy Volunteers and Metastatic Melanoma Patients, Nicholas Gulati

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Plasticity of the Nuclear Pore Complex Revealed With Proteomics, Zhanna Hakhverdyan

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Dynamics of HIV-1 Infection and Therapy In Vivo, Joshua Abraham Horwitz

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Natural Products From Functional Screening of Soil Metagenomic Libraries, Hala Iqbal

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CPISPR-CAS: From a Prokaryotic Immune System to a Gene Editing Tool, Wenyan Jiang

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Aversive Olfactory Imprinting in Caenorhabditis Elegans, Xin Jin

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Regulatory Architecture of Non-Apoptotic Cell Death Program in C. Elegans, Maxime Jeremie Kinet

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Extracellular Metabolic Energetics Can Promote Cancer Progression, Jia Min Loo

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Paleovirological Analyses of Endogenous Retroviruses and Host Innate Immune Effectors, Daniel Blanco Melo

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Tracking the In Vivo Dynamics of Antigenic Variation in the African Trypanosome, Monica R. Mugnier

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Genetic Dissection of Neural Circuits Underlying Value Based Decision Making, Hirofumi Nakayama

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Characterization of Mechanisms That Mediate Cancer Metastatic Colonization, Alexander Huan Nguyen

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Structural and Functional Characterization of SPOA Domains in Salmonella Typhimurium Type III Secretion Systems, Ryan Q. Notti

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Regulation of the Anaphase-Promoting Complex Examined at the Single Cell Level, Andrej Ondracka

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Retrograde Activation of a Somatic Transcriptional Program Regulates Distal Axon Degeneration, Jason Pitts

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Protein Regulators of Phosphoinositides as Promoters of Cancer Metastasis, Caitlin Anne Sengelaub

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Analysis of Hepatocyte Secretion Pathways: A Case Study on Hepatic Apolipoproteins, Serum Albumin, and Hepatitis C Virus, Constantin N. Takacs

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Reconstitution and Mechanistic Studies on the Staphylococcal agr Quorum Sensing Circuit, Boyuan Wang

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Chemical Tools for Exploring IFITM3 S-Palmitoylation and Mechanism, Xiaoqiu Yuan

2015

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Why Mosquitoes Bite Some People More Than Others: Metabolic Correlates of Human Attraction in AEDES AEGYPTI, Lindsay Lee Bellani

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Mechanism of Action of ING4 as a Transcriptional Coactivator of p53, Jabez Bok

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Metagenomics-Based Tryptophan Dimer Natural Product Discovery and Development Pipeline, Fang-Yuan Chang

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Mechanisms of Olfactory Plasticity in Caenorhabditis Elegans, Christine Cho

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Synapse Formation in the Zebrafish Lateral Line, Eliot Dow

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Normalization Among Heterogeneous Population Confers Stimulus Discriminability on the Macaque Face Patch Neurons, Akinori F. Ebihara

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Effects of Temporal and Spatial Context Within the Macaque Face-Processing System, Clark Andrew Fisher

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Studies on the Maturation of Secreted Quorum Sensing Peptides That Regulates S. Aureus Virulence, Jeffrey Grant Johnson

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Investigating Mechanisms of Telomere End-Protection, Shaheen Kabir

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The Effect of Chronic Hypertension on Neuropathology in the TGSWDI Mouse Model of Alzheimer's Disease, Anna Kruyer

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A Mechanism for Spatial Orientation Based on Sensory Adaptation in Caenorhabditis Elegans, Johannes Larsch

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Identification of TMEM2 as a SOX4 Transcriptional Target Involved in Breast Cancer Metastasis, Hyeseung Lee

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Hair Bundles of a Jawless Vertebrate Employ Tetrapod-Like Tuned Mechanical Amplification, Katherine J. Leitch

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A Genomic Portrait of Hepatitis C Virus and MicroRNA-122, Joseph M. Luna

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Functional Dissection of Brainstem Circuitry, Alexander Ryan Nectow

A Reductionist Approach to Modeling Human Corticogenesis, Mohammad Zeeshan Ozair

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Characterization of Bacterial Metabolites Involved in Host Pathogen Resistance, Kavita J. Rangan

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Molecular Determinants of Tumor Re-Initiation in Breast Cancer, Jason Barzel Ross

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Mechanical Control of Sensory Hair-Bundle Function, Joshua D. Salvi

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Activity Based Profiling: New Insights into Metabolic Homeostasis, Keith Tan

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Xenopus DPPA2 is a Direct Inhibitor of Microtubule Polymerization Required for Nuclear Assembly, John Zhao Xue

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A New Role for Beta-Amyloid in Alzheimer's Disease: Initiation of Thrombotic and Inflammatory Processes Via Coagulation Factor XII and Fibrinogen, Daria Zamolodchikov

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Components of the Ubiquitin Proteasome System are Required for the Nonapoptotic Death of the C. Elegans Linker Cell, Jennifer Zuckerman Malin

2014

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Abdominal-B Neurons Control Drosophila Virgin Female Receptivity, Jennifer J. Bussell

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Stochastic Activation of Enhancers in the Innate Immune Response by the Histone Demethylase JMJD2D, Rohit Chandwani

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Coordinating Stem Cell Behavior in the Hair Follicle, Chiung-Ying Chang

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Taming a Potent Mutator: Identification and Characterization of Novel Mechanisms of Regulating Antibody Diversification in B-Lymphocytes, Rebecca Kyle Delker

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Genome-Wide Characterization of the Effects of Nucleic Acid Modifying Enzymes: Cytidine Deaminases and DNA Methylation, Eric Luke Fritz

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Mutations in a Mechanosensitive Channel Enable Intravascular Metaststic Cell Survival, Paul William Furlow

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Studies of a Novel Phage Lytic Enzyme, PlySs2, Daniel B. Gilmer

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Transcriptome-Wide Characterization of APOBEC1-Catalyzed RNA Editing Events in Macrophages, Claire Ellen Hamilton

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Forces Generated by Cell Intercalculation Tow Epidermal Sheets in Mammalian Tissue Morphogenesis, Evan Heller

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Chromatin Control of the Antiviral Response to Influenza, Jessica Sook Yuin Ho

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Identification of a Functional Hotspot on Ubiquitin Required for Stimulation of Methyltransferase Activity on Chromatin, Matthew Thomas Holt

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High Resolution Maps of the Vasculature of An Entire Organ, Oppenheim N. Jacob

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The Structural and Biochemical Characterization of Salmonella Host Specificity Determinant Gifsy-2 Gene E, Amanda C. Kohler

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Functional and Structural Studies of the Human Voltage-Gated Proton Channel, James Anthony Letts

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The Neuropeptide Regulation of Host-Seeking Behavior in Aedes Aegypti Mosquitoes, Jeff Liesch

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RNA Deregulation in Metastatic Breast Cancer, Christina Beate Marney

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The Origin of Multiple Sclerosis Revisited: The Case for a Soluble Toxin, Kareem Rashid Rumah

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HIV Specific B Cell Response in Patients With Broadly Neutralizing Serum Activity, Johannes F. Scheid

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Split Inteins: From Mechanistic Studies to Novel Protein Engineering Technologies, Neel H. Shah

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Exploration of Cell Cycle-Specific Essential Gene Functions in the Microbial Plant Chlamydomonas Reinhardtii, Frej Tulin

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Mechanism and Evolutionary Origins of HIV-1 Virion Entrapment by Tetherin, Siddarth Venkatesh

2013

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Decoding 5HMC as an Active Chromatin Mark in the Brain and its Link to Rett Syndrome, Pinar Ayata

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Cannabinoid CB1R Receptor Mediates Metabolic Syndrome in Models of Circadian and Glucocorticoid Dysregulation, Nicole Bowles

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Discovery and Characterization of Methylation of Arginine 42 on Histone H3: A Novel Histone Modification with Positive Transcriptional Effects, Fabio Casadio

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Telomere-Driven Tetraploidy and its Relevance to Cancer, Teresa Davoli

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Analysis of Small Molecule Inhibitors Aimed at Bacterial Virulence, Paul Daniel Dossa

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Mechanism of Translational Control by the Fragile X Mental Retardation Protein and Creation of the FMRP CTAG Mouse, Sarah Van Driesche

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RNA Dynamics in T Cell Activation, Emily Conn Gantman